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Gabapentinoids The Lyrica (Pregabalin) Mega Thread v 2.0

We have the same brain chemistry. Never understood people taking benzos recreative. I just take them as a sleeping aid very occasionaly. And alcohol, well sometimes it does the job, but most times it is just a numbness without much interesting anything going on. As a way to change conciousness it is clearly overated IMO. But I kind of love single malts and some expensive beers.

I used to love GHB, took a lot of it and never gave me any adiction or inconveniences..., well I passed out a couple of times because of redosing. Then it started giving me worrying stomach pains. Had to end up throwing it away, nobody wanted it. I know it is a very difficult to dose drug and you cannot mix with alcohol, but I never understood it was not more popular. It is DESHINIBITION with capital letters. Never ordered again. That was 10 years ago. So ya, sometimes I miss it. Problem is the minimum purchase it is far too much. And if I get the pain again it would be worthless. One day we will cross paths, I'll wait patiently.

And opium, well he is second to nothing. He is the king wiping out suffering and producing PLEASURE. He doesn't threat me as he used to as I knocked to much in his door. But he didn't spank me really bad for that to be honest, I am one of the lucky ones who got away quite easily. But still he is for me like a good old lover.

I do use benzos for recreationally occasionally, because sometimes they do give some kind of gaba pleasure, the sedation and relaxed feeling, but other times it make me feel crappy. It depends on benzo, etziolam in my experience gives even euphoric feeling and very nice gaba relaxation. Yes for me too alcohol sometimes gives even GHB like high for a short time, especially when drinking high quality vodka, but very rarely. Sometimes even one beer gives nice relaxation, but most times it makes me feel not good, like bad unclean high of benzos.

Opium is only opioid I ever have liked along with kratom, I've tried oxycodone and fentanyl and 10 other differnet opioids (never heroin I don't try it even if offered money), they weren't for me, but oh the nice poppy, that was my daily companion for three years, had to quit eventually it started to cost too much and I got very bad migraine headache for 2 days every now and then from it. I still use it time to time, but then I need pregablin to take 5 day mild wd hungover away. But I really miss kratom, I haven't done it for over 10 years, because its very hard to get in here, well maybe next time when I go to SE-Asia I find someone who has it.

Last year I found that GBL gave me even greater pleasure than ever before (I had 6 years break from it because of availability), even better than first time very very euphoric high much better than what you get from speed. I really like it, but there is no GBL available to buy in my local market, so I haven used it for a long time, I still try to find some 20ml GBL just for few day use and enjoy it all over again.


Pregabalin makes me sleep like a baby...so not crossing my mind such thing.

Interesting me pregabalin makes first stimulated but after that sedated, it varies, sometimes the effect is different than normally, one time it even felt like opioid high, all depends on tolerance too ofc, it's interesting drug.
 
Does pregabalin have crosstolerance with gabapentin? because I just took 3500g gabapentin and don't feel much, maybe little warm on my feets, I had 1500mg daily binge with pregabalin, maybe thats the reason? Or did I got scammed (bough from street).
 
Ya, it does have crosstolerance. Actually with all gabaergics and probably with gabapentin the most as they are both gabapentinoids and have similar mechanism of action and effects.
 
Ya, it does have crosstolerance. Actually with all gabaergics and probably with gabapentin the most as they are both gabapentinoids and have similar mechanism of action and effects.

Ok I see I took 4 hours ago 3600mg gabapentin every 1 hour 800mg with fat meal, and then I took 300 mg pregabalin 1 hour ago I ytet can't feel much, but let's hope this combo gives me something. I got shit loads of methylpphenidate, so I took 56mg depot (I always prefer depot drugs, because of more smooth effects), I hope it plays all well. I report back.
 
Neo- I'm not trying to judge, but it doesn't matter if your meds are prescribed. Driving under the influence is illegal. Ask any police officer- if you're impaired and it's because of anything your Dr prescribed, it's the same as driving drunk. I do it every day, but it is against the law. People get DUI's on Listerene(mouthwash). You can get a DUI on cough syrup, while riding a bicycle. It's a little stupid if you ask me, but it is the law and cops LOVE to give DUI's.
If you get pulled ovet DO NOT admit to having taken any pills. There's no law against being a bad driver. Just take your ticket and go home. If you tell the cop that you're on anything, his story will suddenly change and you will have been swerving and slurring your words.
 
About the gabaergics cross tolerance...Yesterday I drank a bit of alcohol, it had been quite long since I have drunk so the effect was quite strong though I just drank one beer, one glass of wine and one shot of spirit. Well 3 hours after that I tried to get a bit high with pregabalin and it was useless. I took double the dose of the day before (750mg) and didn't feel it much. Just tolerance from one day 300mg, it seems it doesn't work after drinking.
Today I went for 1 gram of Phenibut and I felt the effect as usual, didn't perceive any tolerance. It seems cross tolerance between pregabalin and Phenibut is not very acute.

It is quite strange I would have guessed that pregabalin would have more cross tolerance with Phenibut than alcohol based on the nature of the effect.
 
Fuck got bad WD's from 1 month heavy daily pregabalin use, I now jumped back to opioids, I much rather quit opioids than pregabalin, at least I can use then GHB, but with this shitty pregablin bullshit, I think it wouldnt work.
 
I apologize as I did not read the entire thread but I know there have been some questions on OD safety.
https://psychonautwiki.org/wiki/Pregabalin
Pregabalin
Lethal dosage
Both rat and mouse oral acute LD50 have been established to be greater than 5000mg/kg. Rat IV LD50 was also determined to be greater than 300mg/kg.[15]
In terms of humans, there exists a case report of a man who ingested 8,400mg pregabalin and eventually fell into a coma but was managed with supportive care alone until he regained consciousness.[16] For comparison, the maximum recommended a therapeutic dose of pregabalin is 300mg twice per day. Another case report details a man's suicide attempt with the co-ingestion of an estimated 11.5 grams of pregabalin and 32 grams of lamotrigine, another anti-epileptic agent which, by blocking sodium channels, lowers glutamate levels similar to pregabalin. He presented with a reduced level of consciousness and an aggressive demeanor when not sedated. Eventually, he suffered respiratory problems that required intubation and ventilation. After 28 days in the hospital (19 of which were in the intensive care unit) the man was discharged from the hospital. The man suffered seizures which were attributed to his underlying epilepsy.[17] Pfizer's official package insert for Lyrica states that the highest accidental ingestion of pregabalin during clinical trials was 8 g, with no significant consequences.[18]
 
Fuck got bad WD's from 1 month heavy daily pregabalin use, I now jumped back to opioids, I much rather quit opioids than pregabalin, at least I can use then GHB, but with this shitty pregablin bullshit, I think it wouldnt work.
How are you doing? hope you are fine by now.
It would be interesting if you can describe whatever withdrawal symptoms you got and how they compared to an opioids withdrawal.
 
This drug gives pretty strong cravings it seems. feeling shit today took only 150mg but I get 2100mg in one hour, so I might take 1500mg on more time then there is so little left that I take only 300 mg for two days and then Im off lets hope it helps. But not sure because I took poppytea 4day binges two times in two weeks, and I got WDs from it so maybe its only opioid WD that pregabalin takes away totally, really hard to tell. It surely feels like mild opioid WD. But I don't think one week of pregabalin using doses 800-1500 mg should give anything like that, I need to start work next week if I'm still not ok and as there is no any pregabalin left on my prescript, so I hope I don't have to go back to poppy tea as there isn't anything else to help feeling better (I can get different benzos but they are useless), I can't think quitting poppy second time.

Here is an example of what not to do. This thread is for the discussion of dosages, effects, withdrawal, etc, not hose sizing.


Since this thread is old enough, a version 3.0 will be coming soon.

Stick to the point. Practice phrasing.

Some people have "more than normally prescribed" dosages. If you are one of them, please phrase correctly.

Abuse will not be tolerated.
 
With all my respect, I might not have understood well your ''phrasing'' so correct me if I am wrong. Things like hose sizing not even google understand them...

Are you saying that people abusing the drug are not welcome to share their experiences?
 
It seems there is a difference between sharing experiences and bragging about self destructive behavior.
Also, though I am sure I too am guilty of getting off-topic, this thread should be limited to Lyrica/Pregabalin. Neo's comments do have a place at Bluelight but that place seems more appropriate somewhere in the 'Dark Side'.
 
^Ooh, SK, harsh. Lol. Never see you on the pain threads any more. Hope that's bcos ur doing well?.

^^Neo, it's a little confusing when you say what may be wd symptoms from pregabalin are worse than opi wds,- then go on to post that you'd not bear to think of quitting poppy tea again.

Lyrica is excellent at covering opiate wd symptoms, I have previously posted many times how I've bridged between script.

Perhaps try to keep your binges of whatever substance to the lowest dose that works for you, & take a day or two off every now & then.

Hope you're feeling alright now. As an above poster asked, could you compare & describe the wd symptoms you're experiencing with lyrica to pod tea? Or are you unsure of what one you're actually wding from?

Rtp
 
Everything is fine. You are correct about how to share. Braggarts do not reduce harm.
In the new thread then you can draw some nice lines nobody can cross then. Good luck with that one. There is a huge difference between bragging and abusing IMO. I myself don't use pregabalin as prescripted, have my reasons for it and I am quite sure I am not bragging. That a drug is a prescription drug doesn't invalidate it as a recreative one. Or make that use wrong by itself.
 
Hey everyone.

Some quick background material. I am an recovering addict - I am on 60 mg methadone and 2 mg clonazepam daily.

Together with my addiction I am suffering from epilepsy and a variety of psychological disorders including anxiety.

My job requires a lot of international travel, and traveling is connected with severe anxiety for me due to some bad experiences earlier in my life. Last time I was traveling I got so wound up before leaving home that I turned back to some old addictive behaviors. Together with my normal dosage of methadone I took 240 mg oxycodone (2x120 mg OxyContin). It took me several weeks before I stopped this and got back to taking methadone only. It was mainly my anxiety for the upcoming traveling that triggered my "down fall".

Normally the clonazepam should handle the anxiety. But it starts to seem like this isn't enough anymore. I am experiencing small cases of panic attacks again as well. I would like to avoid increasing my dosage of clonazepam.

I discovered that pregabalin have been approved for anxiety treatment now. Hence, my questions:

Do anyone have experience with the use of pregabalin for anxiety - maybe in combination with a benzodiapine?

I have tried pregabalin before - to see if it have any recreational value - and it absolutely have no effects in that regard whatsoever for me, therefore I am not that afraid of adding pregabalin to the mix in regards of psychological addiction. I do not know if pregabalin have any psyhical withdraval symptoms however or if it is hard to stop taking after a longer period of prescribed use?

The alternative to pregabalin every day would be some alprazolam in the days I am traveling, but as an addict I know that is one of the most dangerous benzodiazepines to add into the mix and I could see myself ending up needing a dose of that everyday as well. I will have to address the travel matter in therapy obvisoly. I cannot avoid it and it will continue to be part of my job. However, this is not exactly a quick fix.
 
Yeah, I get it weekly and usually blow through my 2100mg in 3 days and have to go 4 days without or use phenibut.
 
Hey everyone.

Some quick background material. I am an recovering addict - I am on 60 mg methadone and 2 mg clonazepam daily.

Together with my addiction I am suffering from epilepsy and a variety of psychological disorders including anxiety.

My job requires a lot of international travel, and traveling is connected with severe anxiety for me due to some bad experiences earlier in my life. Last time I was traveling I got so wound up before leaving home that I turned back to some old addictive behaviors. Together with my normal dosage of methadone I took 240 mg oxycodone (2x120 mg OxyContin). It took me several weeks before I stopped this and got back to taking methadone only. It was mainly my anxiety for the upcoming traveling that triggered my "down fall".

Normally the clonazepam should handle the anxiety. But it starts to seem like this isn't enough anymore. I am experiencing small cases of panic attacks again as well. I would like to avoid increasing my dosage of clonazepam.

I discovered that pregabalin have been approved for anxiety treatment now. Hence, my questions:

Do anyone have experience with the use of pregabalin for anxiety - maybe in combination with a benzodiapine?

I have tried pregabalin before - to see if it have any recreational value - and it absolutely have no effects in that regard whatsoever for me, therefore I am not that afraid of adding pregabalin to the mix in regards of psychological addiction. I do not know if pregabalin have any psyhical withdraval symptoms however or if it is hard to stop taking after a longer period of prescribed use?

The alternative to pregabalin every day would be some alprazolam in the days I am traveling, but as an addict I know that is one of the most dangerous benzodiazepines to add into the mix and I could see myself ending up needing a dose of that everyday as well. I will have to address the travel matter in therapy obvisoly. I cannot avoid it and it will continue to be part of my job. However, this is not exactly a quick fix.



I think you should give it a try. It definitely works for some people for anxiety. It can cause dependence, but if you follow your prescribed dosages and tapper at the end of the cycle you should be alright. It affects different people in very different ways, so some people report no withdrawal meanwhile others complain about bad depressive states especially. Psyquiatrists always recommend taking it daily, but if your anxiety is situacional, you might take it only when you travel and maybe avoid addiction. Take that with a pinch of salt...maybe just follow your psyquiatrist advice...but still think peoople with no risk of abuse could benefit by incidental use.

It definitely has recreative value so be careful in that department. Lots of people take big doses, far higher than their prescription and are left with nothing for the rest of the period.

IMO is preferable to benzo usage, more functional, better mood enhancer and much less risky. It is quite usual to have prescribed both. Pregabalin during the day and benzo for sleep.
 
Thanks for your reply. Even with my benzo dosage I will get seizures if I take large dosages of pregabalin (I learned this the hard way), so I can't get near the dosages required to feel the recreational effects..

I get seriously physical withdrawal effects from tramadol (especially it becomes impossible for me to sleep due to severe restless leg syndrome) and I become very depressed. I have experienced pregabalin doing the same with restless leg syndrome. Therefore I fear I might be one of those who will suffer severe withdrawal from pregabalin. The good thing with me being so sensitive to tramadol is that oxycodone and morphine does not give me so severe withdrawal syndroms as soon as I am past the typical physical symptoms like puking etc.

Anyway, as I have it currently I am willing to try pregabalin. I still have to tapper out of methadone and maybe clonazepam one day plus I get low dose Quetiapin to sleep so adding one more to the mix seems to see like a small thing - But I recon that is the addict constantly sitting on my shoulder leading me to believe this :)

(And sometimes I think that - realistically - I am never going to be able to tapper out of either methadone nor clonazepam)
 
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I'm quite skeptical of Lyrica (and Gabapentin, which has been shown to be no inferior than Lyrica. Pfizer's Gabapentin patent expired. Watch, once Lyrica's does, a Lyrica XR will come out!) but anyway I'm not a big fan of it. It hasn't really been shown to be all that effective in nerve pain, Gabapentin was sold off-label as an Epilepsy med, an anxiety med, etc, and docs use both Gabapentin and Lyrica still off-label for anxiety when flawed studies have concluded it's better than Bromazepam, a weak benzo anyway!

Anyway I have lots of nerve damage and have been on very high doses of both (though I finally just stuck to Gabapentin but since we are speaking of Lyrica) The only thing Lyrica has done for me that I like is getting rid of hot flashes due to my opioids. I have major nerve damage in my right foot, to where I can't feel half and the other half is burning on fire, I've got Sciatica, and definitely nerve pain from the bottom of my right thigh and all the way down.

Lyrica never helped. I think it's overprescribed and I think a lot of people should try tapering and they'd be shocked at how it doesn't help! For RLS and hot flashes, yes, for DIABETIC nerve pain, slightly, but that's it!

I've abused it before and the feeling was weird... in fact, I couldn't even talk properly. I slurred like crazy. Was a little high but remembered everything.

Oh and another thing... it has w/d symptoms after prolonged use that are similar to benzo withdrawals. Right now a lot of docs are trying to prescribe lyrica instead of benzos for its "anxiety relief" (yeah, temporary) but right now it's just loved by docs. One day these folks who have been on it for years will suffer horrible withdrawals and we will see what a mistake we made in over glorifying it!

If you've been Rxed Lyrica for over a year, has your dose gone up? Because with me, they'd ask "how is the Lyrica" and I'd say "not doing a thing" and they'd raise it every time. Sorry but if it has to be raised all the time perhaps it just isn't working!

I know, my post is all over the place. Sorry! Lol
 
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