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Psychedelics with antipsychotics - Do NOT waste your time or risk it.

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tritonenneptunus

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Mar 11, 2016
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I decided against my better judgement to take LSD tonight on top of my medicine and I want to warn all others who take anti-psychotics that it is a waste of time. I took 4 blotters and I started to feel it a little but then I guess my medications kicked in. So I really highly advise against it because it's not only dangerous but it can also be a waste. Please stay safe guys and the people on this forum know what they are talking about!
 
tritonenneptunus said:
I decided against my better judgement to take LSD tonight on top of my medicine and I want to warn all others who take anti-psychotics that it is a waste of time. I took 4 blotters and I started to feel it a little but then I guess my medications kicked in. So I really highly advise against it because it's not only dangerous but it can also be a waste. Please stay safe guys and the people on this forum know what they are talking about!
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Thanks for sharing. This should really be a given, I firmly believe that psychedelics serve you best when the mind and body is healthy, in a calm and natural state.

Mixing compounds could lead to some very detrimental effects. Always research before you dive in. I disregarded this once and was lucky enough to come out of it unscathed, but trust me, you'd really rather avoid a bad trip altogether. The bad trip was not because of Lucy, but because of my own poor judgement.
 
LostAtomsk said:
Thanks for sharing. This should really be a given, I firmly believe that psychedelics serve you best when the mind and body is healthy, in a calm and natural state.

Mixing compounds could lead to some very detrimental effects. Always research before you dive in. I disregarded this once and was lucky enough to come out of it unscathed, but trust me, you'd really rather avoid a bad trip altogether. The bad trip was not because of Lucy, but because of my own poor judgement.
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I completely agree. It could have been really disastrous. That's why I do urge people to listen to the warnings you guys have given. It was a really dumb choice for me to do what I did. I hope my experience can help discourage others on psychiatric medicines from trying to use drugs. Thank you guys for giving the advice you give and I hope others will listen when people say "hey that's a REALLY bad idea!"
 
I think there's a chance of hypertension when combining some psychedelics with anti-psychotic, but LSD should be okay from what I understand. Apart from not being able to trip, that is.
 
People often use anti-psychotics to terminate bad trips, usually quetiapine, and I have not heard of harmful interactions
 
I can understand hypertension happening with the mixture, but that's what I'm saying of it being a waste, why would you want to waste money on something and not be able to experience the full effects. I just think that it's not a good idea and it makes sense that people use anti-psychotics to terminate their trips because I felt warm and something like a deeply warm and connectedness with everything around me but in a flash that was gone so I'm thinking that I'm probably not going to experiment with any more psychedelics. By the way, the medication I took it on was Zyprexa which is for schizophrenia (I don't have schizophrenia just Bipolar) I felt kind of manic by the end of the night but I just took my meds and was fine. Went to sleep and everything.
 
Yea smart move and not continuing using while you are on medication, waste of money and mental energy for sure and there definitely could be rare interactions between these drugs which I am ignorant of.
 
I remember reading something from the 60s about chlorpromazine (typical-antipsychotic) and DOM being contraindicated. There have been hospitalizations from the combo. Zyprexa, Haldol and Seroquel (atypical-antipsychotics) should be safer though. Still,

Zyprexa is pretty heavy stuff, I wouldn't experiment with any drug before researching interactions. There are many possible ways it can go wrong. If I may, it would be wiser to wait until you're without this medication.
 
I think a safer bet for 'trip abortion' is Valium or other benzodiazepines. Ok it won't remove all effects, but it will make you very calm, and usually the effects that are left are now enjoyable. Psychological and physical risks of interaction are very low provided you've not taken other downers too.

Taking anti-psychotics or other similar medications to abort trips might potentially remove effects completely, but serious physical and strange psychological reactions seem much more common when doing this.
 
5ht2a antagonist beurk. Can always have a nice nmda ant ��

Bless
 
I added to the title of this thread since the original title didn't really indicate what this is talking about and I think it deserves to be found when searching for the topic. :)
 
What antipsychotic did you take? Not all of them can block the effects of LSD.
 
I have tripped on antipsychotics, it really depends on the dose. Right now I just do 50-75mg seroquel at bedtime, let's me sleep a few hours. If I plan on tripping I skip a couple days.

At one point I was on high dose zyprexa. Gained weight, made weed suck and psychedelics worthless.
 
terarc said:
I think a safer bet for 'trip abortion' is Valium or other benzodiazepines. Ok it won't remove all effects, but it will make you very calm, and usually the effects that are left are now enjoyable. Psychological and physical risks of interaction are very low provided you've not taken other downers too.

Taking anti-psychotics or other similar medications to abort trips might potentially remove effects completely, but serious physical and strange psychological reactions seem much more common when doing this.
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I'd say that anti-psychotics (taken as trip aborters) don't really abort the trip as much as it just sedates you and makes it physically uncomfortable.

For example: I've used Seroquel to end trips and all that happened when I did? It made me completely unable to move, speak, or think. I was conscious but completely unable to do anything. Worse, I kept feeling like I couldn't breathe.

It's dangerous to use antipsychotics as a trip aborter.

(I'm also bipolar I, and I took to heart that it was dangerous to trip at all, so I stopped and haven't for awhile)
 
Take enough lsd to overpower the antipsychotics. They both compete for the same receptor site. I take 20 mg apiprazole and need 500 mcg lsd for decent visuals (just like taking 250 mcg without the antipsychotics) Good luck--
 
Unicorndragon said:
Take enough lsd to overpower the antipsychotics. They both compete for the same receptor site...........
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I'm not a chemist so don't really understand what going on at the receptor level ....... however I can see the logic in taking enough of a substance to compete and dominate.Does this then mean that the other substance - in this case the anti-psychotic - is excluded for the duration and could this lead to the unwanted symptoms that the anti-psychotic masks, bleeding through? Or does missing one dose - which this seems to me to be akin to, not make a lot of difference? I'd hate to think that some of the psychotic symptoms - even if just a little - crept into a trip!
 
tritonenneptunus said:
I decided against my better judgement to take LSD tonight on top of my medicine and I want to warn all others who take anti-psychotics that it is a waste of time. I took 4 blotters and I started to feel it a little but then I guess my medications kicked in.
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May I ask which anti-psychotics you were on, and the strength and type of LSD? Was it fresh, or did you maybe have it laying around for a while? Let's see if we can figure out how and why this happened. There are people reading this thread who are on medicine(s) for which your advice may not apply.

Seems like a great opportunity to create an anti-psychotics / psychedelics spreadsheet that we can all update and share.
 
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You probably got bunk acid. Antipsychotics are a truly invaluable tool at the tail end of a trip (bad or not) or speed binge.
 
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