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Social The Delphic Oracle - Know Thyself: P&S Social Ampitheatre of Doom

This board seems very busy lately. This time last year it was just me and a handful of regulars.
 
swilow said:
Interesting brief plummett into dire black mood today. It honestly feels like I am not thinking the thoughts I am, they are just running as if automated. And its ridiculous, depressing, despairing shit. I shared about with my gentle Miss and I really shouldn't've.
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I had something like that before I started practicing Zen and shadow work. When you harbour a lot of negative energy it seems to take over your thought processes so clearing yourself can really help. Also, Mindfulness practices like meditation can help make the mind more still and create more "space" between thoughts.

I don't really have racing thoughts any more, and rarely downward spiralling, negative thoughts. It's a real disease.
 
Even though drug testing discussion is not really acceptable, I think it's OK to talk about pharmacokinetics of drugs. Cannabinoids, also like some more lipophilic benzos (a la diazepam), tend to get stored in the fat tissue during usage, so the concept of a half-life doesn't really apply to them. Yes, they do linger in the system for quite some time, and a drug test can reveal THC or diazepam usage weeks after the ingestion, which is of course absolutely bonkers given the consequences.

Salt-forming and otherwise polar drugs, like PCP or cousins, exit the body a lot faster, so a few days should mean you're clear off them. Codeine/morphine/heroin falls into this category.
 
Well fellas, I did end up getting my wisdom teeth out. I have more pain killers than I know what to do with, so I'm just going to take it easy. I've been taking motrin for pain. Haven't had any hydrocodone at all.

Kind of proud of myself, too bad I'm about to ruin that streak.

I'd real quick like to thank all of you for being an amazing company, being such an open community where anyone and everyone can confide things they wouldn't tell their family, and providing insightful, and intelligent responses.

I'm more than likely going to pass out now. Popping a couple pills and I'll be asleep in no time.

Legal btw, prescribed.

I almost feel as if Bluelight, and more specifically P&S is about to turn over a new leaf in amazing dicsussion.

See you guys in the forums.
 
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Ow. I dunno what I did to my back.

Over did it a bit with the oxy and hydro yesterday. Didn't realize how much I had taken until my breath was shallow. All okay though, lesson learned. Got a bit crazy.

I'm taking it hella easy today, I have no inclination to indulge myself in drugs at this moment.

I have so many pain killers left, just saving them for a rainy day. No Idea why they prescribed me this many.

Anyways, how's everyone? P&S seems to be runnin slow. Guess it's just that time of the year.

I feel like something cool is nearing our future.
 
I'm doing good. Did a lot of work today, even though it's like a national holiday and Saturday, but the likes of me give no fucks about things such as those. Lowering my codeine tolerance, first day without any in the last 40-50 days. Not that bad actually, got some loperamide on hand. Without loperamide, I tried quitting CT this year a few times and it was absolute hell - especially the extreme dehydration from non-stop diarrhea. But then when I went to Greece, I quit CT with the help of loperamide without any problems (almost 10 days without it). I think you can remember me whining about it here, because I was bored and drunk, but in hindsight it wasn't that bad.

I feel a little bit stupid and guilty for getting right back on track with the codeine after coming back from Greece, because I had finally got myself unhooked. But no, the first thing I did when I came home was get me codeine. Literally. Dropped all my things in the apt and went out to buy some, even though it was 2 AM (we have a pharmacy that works 24/7 in the town), and I was tired as all fuck from starting the travel around noon that day (11 hours of travel while hungover, fun fun). I don't know if it was more funny than sad, but been using every day since then.
 
14BD! Working on hollidays! You scientific mad man! I demand to know what it is you're cooking up in the so called "non clandestine" lab, you passionate hippie bearded psychopath posing as a chemist!?!?

lol just jokes. I wish I had a beard.

Hey man, best of luck to you. Besides, nobody likes having a tolerance to anything except maybe alcohol, but even that's only for drinking contests. You shouldn't feel guilty, just be glad it isn't killing you, right?

I assume you're just using the lope for combatting the explosive fecal issues, and not to get high.

That shit'll give you heart failure.
 
Yes, I only use 4-6 mg at a time, once or rarely twice a day, to combat the diarrhea. I know of loperamide's dangers.

I work on different hydrazines most of the time. We try to develop better synthetic methods for precursors for aza-peptides. If it is of interest to you, then aza-peptides are such peptides, in which at least one amino acid is replaced with an aza-amino acid, which means that its alpha carbon has been replaced by a nitrogen, introducing a hydrazine functionality (hydrazide technically, but aza-amino acids themselves are not stable). So we work with those. Not very nasty substances, but dangerous and harmful nonetheless!

Thanks for the good wishes! I also hope your teeth issues resolve soon, and you don't get hooked on opioids.
 
Theoretically, wouldn't loperamide potentiate opiates by binding to peripheral opiate receptors and thus allowing greater activity of centrally active opiates ? B_d, thoughts?
 
It's been discussed before in NPD. The answer is no. The number of receptors compared to the number of ligand molecules is insignficant. Well, if you want to be very strict, then yes, it does work that way - loperamide has higher affinity for peripheral opioid receptors than, say, morphine, I'm pretty sure. So it would occupy that and free up some morphine to go to the CNS, but that would not even be 0.1%. So you would not notice the difference.
 
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B_d, another codeine question. Do you even get a really unpleasant sort of weak feeling when you take it? Sometimes, I simply need to lie down- I go all pale, red eyes, all shaky, anxious thoughts. I think its low blood sugar but... It doesn't happen every time and eating sugar things doesn't really help. Thoughts?
 
Grr, one of my doctors wants to take me off Oxazepam and it's the only thing that makes me sleep. This country sucks. And doctors are completely out of touch with reality if they think Oxazepam is an addictive drug you need to be weaned off.
 
That's not what I meant, I mean it's not like it's such a harmful drug in small doses it's something that is critical to wean yourself off.

Yea, technically it is a benzo, but it doesn't have any of the relaxing effects of a benzo, or really any kind of psychological effect, so it's kind of pointless to treat it like an addictive or abusable drug. Its only use seems to be as a sleep-aid, and of course it's a lifesaver in benzo withdrawal.
 
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