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  • EADD Moderators: Pissed_and_messed | Shinji Ikari

UK Ketamine Shortage

Shambles said:
Good on you indeed, Bear. It's a depressingly common thing to see - or at least get the general whiff of - at events where plenty peeps are plenty whooshy but takes real balls to actually intervene given it's generally a gang of people involved. You iz well 'ard I know but still takes a pair. Nice work, Bear <3
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Usually the gangs play on peoples fuckedupness and are not looking for an actual fight. Much easier for the fuckers to run away and look for the next target.

I'm a proper nice guy :)
 
^ This I know to be true :)

swampdragon said:
That's awful.. is that a common thing? Maybe I should be warier of random hugs. :sus:
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Probably fairly common - hasn't happened to me before but have heard of it happening from others. Plenty peeps will take advantage when the option is presented. In this case it wasn't a random hug - they just wanted a cig so I gave them my baccy pouch which happened to have my weed in as well and they returned the pouch but had swiped all the weed. I wouldn't have minded if they'd rolled a spliff instead of a cig for themselves but taking the lot is a bit mean.
 
I'm back in London town after a month of holiday... does anybody know what the situation is like in here? Do I have to pretend I'm a horse and go to boots asking for k?
 
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Bearlove said:
I hate this so much - I was in a gig one night (a regular of mine) and heard this group of people (standing within a few feet of me) talking about robbing a person who was royally fucked up (she was with friends but she was worse for wear). I was on the dance floor but could see the group working their stuff (few feet in front of me) - few were distracting her friends, few were distracting her as they went for her phone and bag etc - i let them get comfortable and then I did strike down upon thee with great vengeance and furious anger those who attempt to steal from and destroy my sisters. And you will know I am the bearlove when I lay my vengeance upon you!
:D.
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how i imagined it goin down
 
That's a very Bluelight conspiracy theory. You'll get some takers with that, no doubt. :D

Remember that these were treatment-resistant patients though; very much a minority. And unfortunately:

The duration of the effect is still a problem.

Some relapse within days, while others have found they benefit for around three months and have since had additional doses of ketamine.

There are also some serious side-effects including one case of the supply of blood to the brain being interrupted.

"It is exciting, but it's not about to be a routine treatment as where we need to be going is maintaining the response... it's not about to replace prozac."

However, it does offer a new avenue of research into a field that has struggled to find new treatments for depression.
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So it's exciting, yeah. It has been for some time. But a miracle 'cure' it certainly ain't.

The very last thing that I'd like to see is a seriously depressed person reading too much into this and deciding to self-medicate accordingly. I tried it with methoxetamine, and not only does it take regular dosing, it can start to send you loopy in no time.
 
How much MXE and how frequently sammy? I did the same, 50mg-ish once a week for awhile, the glow would last for days, seemed pretty much fine but started to make me feel a bit manic in the end so i stopped
 
I was doing similar amounts about as frequently as you, although I switched to doing it every 3 days and more frequently near the end.

I did it from just after splitting up with my girlfriend until the methoxetamine ban took effect. So the best part of a year. It really helped me get through the worst of times but it made any high periods extremely strange; more so than normal. Delusions of reference being particularly common.
 
Sammy G said:
I was doing similar amounts about as frequently as you, although I switched to doing it every 3 days and more frequently near the end.

I did it from just after splitting up with my girlfriend until the methoxetamine ban took effect. So the best part of a year. It really helped me get through the worst of times but it made any high periods extremely strange; more so than normal. Delusions of reference being particularly common.
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Delusions of reference?
 
Thinking that everyday events hold some special personal, magical significance. Like, I'd go in a shop and I'd pick out certain items to buy, believing that their names carried some sort of 'message'. Or that traffic lights were changing just for me. Or the radio played certain songs just for me, or that people were speaking to me in some kind of code. Yeah. :\

I can get a less extreme version of this (ideas of reference) as part of my usual cycling, the difference being that I can look at things rationally and write it off as madness. In most cases anyhow.

Delusions of grandeur are more my thing most of the time.
 
Ahh yeah i kinda get what you mean

On the topic of wonky-ness, have you ever experienced any random negative dark cold weird wonks before, left feeling baffled, ive had them happen a few times for seemly no reason at all, very rarely, instead of the embracing euphoric uplifting amazing-ness it ends up the opposite,
 
Yeah, I've had that. Always with ket, never with MXE. Although MXE could be fucking weird, it was never as dark for me as ket could be. Diphenidine was bad for that too - it was pretty much ALL darkness, and a load of wank instead of wonk.

Probably why I've never had a ket problem, even in the early 2000s when Manchester was full of the stuff.

I'd kill for some ket now though, tbh.
 
Sammy G said:
The very last thing that I'd like to see is a seriously depressed person reading too much into this and deciding to self-medicate accordingly. I tried it with methoxetamine, and not only does it take regular dosing, it can start to send you loopy in no time.
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Probably also worth pointing out the doses used for depression are even lower (significantly lower in fact) than would ever be used recreationally. I spoke to a fella on the US version of a similar trial of ketamine for depression and the dose was ~15mg from memory (for him - I'd imagine it's somewhat titrated per person). In his case it was supplied as a nasal spray not infused over time which would seem a more viable option - not sure why this trial is sticking with IV other than it makes it impractical for most who might think of self-medicating. Or perhaps they're using higher doses which would involve some wonkiness if given as a single dose. Ket and related drugs do seem to work amazingly for depression (anecdotally and now evidentially) but the benefits come from sub-psychedelic doses not ones you would physically notice.
 
Quite right.

It may also be worth mentioning that it only appears to be effective with a relatively small percentage of people. Apparently there's a blood test which can determine whether or not a patient will respond to the treatment. All to do with a 'fingerprint' in the blood's fatty acids. How about that?

I'm referring to studies carried out on bipolar patients, so whether it'd be true of any other individual suffering from depression is, like many things, beyond my ken.
 
Anecdotally, it does seem to be a very common effect of ketamine (and some related substances) to markedly reduce depression but biplolar is a somewhat different and special case I would suspect. I look forward to the first aMT/ketamine combo therapy being introduced for depression...
 
Well, bipolar depression (I'm referring purely to the depression) shares all of the features of Major Depressive Disorder, and is in most cases indistinguishable from it. So I'd imagine there isn't actually that much difference in terms of ketamine's effectiveness in treating the two. The main difference being that bipolar people can't really use SSRIs for fear of precipitating mania.

I think those holding out hope of a ketamine script should probably fuggeddaboudit, however. :D
 
Back in the day you could order a kilo of 100% pure K from China for £175. Very nice gentleman called Mr Wu, or am I confusing him the George Formby song.

Mr Wu he's got a naughty eye that flickers,
You ought to see it wobble when he's ironing ladys blouses
 
There are also some serious side-effects including one case of the supply of blood to the brain being interrupted.
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Ooooh, that's a concern... where did this come from..?
 
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