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Misc Clonidine withdrawals after only about 3 weeks taking low doses daily?

Bromide

Greenlighter
Joined
Oct 16, 2013
Messages
20
Location
Canada
Hello, I've been using clonidine for about 3 weeks daily. I usually take 0.020 to 0.025 mg in the evening (about 1/4 or 1/5 of a 0.1mg pill).

However, today, I woke up feeling absolutely terrible. I have an insane headache, I feel very depersonalized, a bit nauseous and I feel like my blood pressure and heart rate are spiking up constantly.

Is it possible I'm having withdrawal after such a short period of time? How would I go about minimizing it? Should I simply try to taper for a few days?

If I have to taper, how should I do it and over how many days?

Thanks a lot.
 
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I'm using clonidine on and off since 2 years, at first it was to reduce BP only, then I was scripted it again when I started MMT. I can go weeks without it and I take 0,2mg a day (2 pills) a day, I wore the patch for a while too. I reduce to not daily taking of it if and I can stop it whenever. I know some people struggle stopping using it though. If I stop to take it suddenly I get a lot of the worst symptom of opi withdrawal though, cold sweats.
 
Thanks, yeah I figure I might as well just take a lower and lower dose each day until I take absolutely none. No point in feeling like shit if the withdrawals can be avoided with a taper.

And yeah it really confused me. I did not expect to feel THIS bad at all. On most days I'm taking even less than 0.025mg :\
 
Clonidine is known as britlofex in the UK, I believe. I am thinking of asking for it when I come of Suboxone, as the restlessness is unbearable to me, particularly when trying to sleep. I really had no idea the drug is addictive; are you sure this is so? I'll be taking the drug for 3 weeks, possibly longer, considering the length of a bupe detox, so if it really is addictive then that could be a concern.
 
It's addictive in the sense that it is a BP medication, it lowers it. Rebound heightened BP will occur will all its nasty side effects when removed too fast.

Yeah it's not addictive, it just has rebound affects when discontinued. Clonidine is notoriously bad for this and is one of the reasons it isn't used much by doctors for BP control. Once you start taking it for high BP it will be hard to take anything else because of the rebound affect when getting off of the Clonidine.

IMO Clonidine should be the last drug to use to relieve symptoms of withdrawal because it is hard to get off without having negative rebound affects. I started taking it when I got off pain meds and haven't been able to get off of it since because they can't control my BP without it. Another thing about Clonidine is that tapering doesn't seem to help with the problem. You just have to deal with it and in a case like me, where it gets so high there is no other choice but to use it to get the BP down.

Again this isn't considered being "addicted" because abuse, like taking more or more often then prescribed, is usually what is necessary to meet the normal definition of addiction. You do become dependent but I think there are a lot of drugs that make you dependent on them. When I quit taking Prilosec, my stomach hurts from hyper-acid production caused by the lack of the medicine. If you take anti-depressants and suddenly quit taking them, you will get extremely depressed. I take Benadryl to help me sleep and like other medications that help you sleep but don't necessarily give you a buzz, yet when I quit taking them I can't sleep for several days after I quit. Whether it is physical or psychological, I think all drugs have some kind of negative affects when you quit taking them after you have been for a while.

As you can see Clonidine's negative effects from discontinuation can be just as bad as whatever you are trying to get off so in a way it is similar to taking another opiate(like Suboxone) to get off of an opiate. Yeah it makes the withdrawal easier but does it really if getting off of that drug is just as bad?

If anything, only use Clonidine to relieve opiate WD as a last resort. Anything, even a benzo would be easier to get off of IMO but the doctors will not agree because they say it is another mind altering substance. Like I said a lot of drugs have withdrawal symptoms when discontinued and if it is easier to get off of one like a benzo compared to something like Clonidine, I think you would be better off with the benzo but I am sure many will disagree.

This, like most things related to a drugs effects on different people, is completely subjective and ones reaction and situation may be different so I am just giving an opinion of someone that has taken everything mentioned and what my experience has been. I also know a lot of others that have experienced the same thing. What is good for one person isn't always the best for everyone else.

Good luck and I hope you find something to smooth that out so you aren't suffering. I don't know how it works, but try some valerian root or other herbs that may help. Anything and everything before Clonidine. I think it's effects are probably more from the placebo effect then anything else because it never seemed to help more then something like valerian did and the negatives were far worse.
 
I guess this could explain why it's not commonly used here anymore. I had to request it myself, as its rarely offered for opiate withdrawal. This always struck me as very callous, but I guess there is a reason for it. Anyway, is this stuff actually any good for WD? I've heard it gives you the most terrible lethargy, but I'd rather be lethargic than have RLS.
 
I personally do not think it does anything to relieve the withdrawal symptoms. If you have never taken it before, it will make you feel rather shitty. It will make you very lethargic but it really doesn't relax you like a benzo does. If they do anything they may (and I strongly emphasize may) help you sleep. The last thing it is is some miracle WD relieving drug. Like I said it is probably the worst out there and no better then placebo.
 
Alright I'd just like to add for future reference or in case anyone else is wondering: I've managed to taper off over the past 2 days, basically cutting the dose in half each time. Yesterday I took the smallest dose possible and today I've taken none and I feel absolutely fine (except I feel slightly anxious, but it's very tolerable and could be unrelated).


I also have a question related to clonidine. How many times per week could one use it without developping tolerance or rebound hypertension? It's a great sleep aid and anxiety aid for me for bad days, and I have a lot of pills of it here from an old script. I just really don't want to become dependant on it in any way, but if I could use it a few times a week without issues I definitely would.
 
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I personally do not think it does anything to relieve the withdrawal symptoms. If you have never taken it before, it will make you feel rather shitty. It will make you very lethargic but it really doesn't relax you like a benzo does. If they do anything they may (and I strongly emphasize may) help you sleep. The last thing it is is some miracle WD relieving drug. Like I said it is probably the worst out there and no better then placebo.

Yeah I was kinda under the impression it pretty much eliminates most opiate WD symptoms; it's what the promotional material pretty much says...but we all know how pharma companies like to sell their products. I've done a little research on it, and apparently it inhibits the excess production of noradrenaline that happens in a detox; it's the chemical that gives you that terrible sense of restlessness. So, I guess that could account for the lethargy. Maybe this could be useful as part of a combination. Obviously the drug will do jack shit for the real misery of WD: the black depression, the constant cravings, and of course you're body's temporary inability to produce painkilling endorphins. If you can find drugs that will treat those, cloniidine could be quite valuable, but would be worthless on its own IMO,
 
I've done a little research on it, and apparently it inhibits the excess production of noradrenaline that happens in a detox; it's the chemical that gives you that terrible sense of restlessness. So, I guess that could account for the lethargy.

The lethargy is primarily due to the fall in blood pressure.

I'm personally not much of an opiate user, but I find clonidine absolutely great for counteracting adrenergic stimulant hypertension.
 
I also have a question related to clonidine. How many times per week could one use it without developping tolerance or rebound hypertension? It's a great sleep aid and anxiety aid for me for bad days, and I have a lot of pills of it here from an old script. I just really don't want to become dependant on it in any way, but if I could use it a few times a week without issues I definitely would.

PLEASE DON'T USE CLONIDINE FOR SLEEP! I've used it just as you described and it doesn't take long before you will develop rebound effects. As I mentioned I also used it to relieve withdrawal symptoms and now I can't control my blood pressure without it. Clonidine is an old evil drug with major side effects and it is why most doctors do not use it even for high BP. If they do it is usually a last resort. IMO the doctors that prescribe it for opiate withdrawal are naïve to how it can screw up your BP for life.

I think a lot of people are given Clonidine in rehab and all I have ever heard from anyone is that it is hell so Clonidine must not do a whole lot. It may help some people but it definitely isn't a miracle relief drug so don't get your hopes up if you plan to try it.
 
No source but I have been to many cardiac specialists for my BP and NONE of them wanting me using it for my BP because of the rebound effects and I would assume they are in the know. If a doctor, like a addiction specialist gives you this, they obviously do not know of the negative effects when a cardiac specialist who does, doesn't even recommend it for what the FDA has approved it for high blood pressure. If you talk to any cardiac specialist they will tell you that they do not want to put you on Clonidine because you will never be able to get off of it once you have used it for a sustained period of time because the rebound high BP could kill you. Therefore once you are on Clonidine, you are on it for life. Anytime they try to get me off, my blood pressure is so high that I have to go to emergency room to get it back under control. I know of several other people that have had the same experience.

If there was a source I would not have put IMO. This is just my opinion.

Clonidine is a very old drug like barbiturates and there have been a lot more medicines developed since then that have less side effects. Cardiac specialist do not use Clonidine anymore for the same reasons other doctors don't use barbiturates as they prefer the newer drugs like benzos.

Using Clonidine occasionally is like using Heroin occasionally. There is that fine line that if you cross it, you become addicted/dependent and then you are screwed.
 
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PLEASE DON'T USE CLONIDINE FOR SLEEP! I've used it just as you described and it doesn't take long before you will develop rebound effects. As I mentioned I also used it to relieve withdrawal symptoms and now I can't control my blood pressure without it. Clonidine is an old evil drug with major side effects and it is why most doctors do not use it even for high BP. If they do it is usually a last resort. IMO the doctors that prescribe it for opiate withdrawal are naïve to how it can screw up your BP for life.

I think a lot of people are given Clonidine in rehab and all I have ever heard from anyone is that it is hell so Clonidine must not do a whole lot. It may help some people but it definitely isn't a miracle relief drug so don't get your hopes up if you plan to try it.

Yeah, I think I agree with you on that. I won't be using it again.

Can it really scew BP for life within less than a month or two? I still feel a bit shitty from it, but I hope it all goes to normal soon..

It still amazes me how even taking 0.025mg (quarter of a 0.1mg pill) each evening for 3 weeks gave me massive rebound. That drug sure is horrible.
 
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No source but I have been to many cardiac specialists for my BP and NONE of them wanting me using it for my BP because of the rebound effects and I would assume they are in the know. If a doctor, like a addiction specialist gives you this, they obviously do not know of the negative effects when a cardiac specialist who does, doesn't even recommend it for what the FDA has approved it for high blood pressure. If you talk to any cardiac specialist they will tell you that they do not want to put you on Clonidine because you will never be able to get off of it once you have used it for a sustained period of time because the rebound high BP could kill you. Therefore once you are on Clonidine, you are on it for life. Anytime they try to get me off, my blood pressure is so high that I have to go to emergency room to get it back under control. I know of several other people that have had the same experience.

Ah, well that does make more sense. But coming off it even in a case like this should (as far as I can tell) be as simple as slowly switching to another (less dependence building) antihypertensive and then tapering. Continuing the heroin analogy, propranlol is a bit like methadone here haha.
 
I couldn't do without clonidine, it takes care of my most feared WD effect : cold sweats, especially in my upper back.....horrible just to think of it, but right now I am feeling very good, I even managed to nod after lifting some weights, 0.1mg clonidine, 1mg clonazepam and 0.5mg xanax over my 10mg of suboxone. I think it is one of the basic comfort meds one should have, you won't get massive WD symptoms from it if you take it only as needed or whatever the short prescription the doc will give you while start MMT/BMT inpatient (that's how they do it here....and I happened to be the only one who was there for opiate, had to live 6 days with cocaine sluts who were saying their withdrawals were worse than mine and old brain rotten alcoholics..ugh).
 
Ok this is weird but I've randomly started feeling like crap again. Not as bad as before, but my blood pressure and heart rate are way up again, eyes bloodshot, tremors...

So I guess I'll continue tapering. This is really lame.

Any idea what would be a good taper schedule starting from 0.025mg/day? Should I take 0.025 in the evening and gradually reduce it over a week or two? Or would eating 0.012 twice a day be better?
 
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Ok this is weird but I've randomly started feeling like crap again. Not as bad as before, but my blood pressure and heart rate are way up again, eyes bloodshot, tremors...

So I guess I'll continue tapering. This is really lame.

Any idea what would be a good taper schedule starting from 0.025mg/day? Should I take 0.025 in the evening and gradually reduce it over a week or two? Or would eating 0.012 twice a day be better?

Sorry about this ordeal with you and clonidine. I'd go with the latter due to the small length of action of clonidine (maybe 3 hours ?). Got a little pocket money ? I'd go buy a couple bottles of Marley's Mellow Mood and down them one after the other...there's tons of things in that yummy black tea to help you go through withdrawals. I'm not kidding, they help me when i'm out of benzos for up to a week.
 
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