• 💊 OTHER DRUGS 💊 Welcome Guest
    Posting Rules Bluelight Rules
    Notable Threads 1 Notable Threads 2
    Dangerous Combos Addiction Support
    Emergency Services Benzo Guide v.1
    Addiction Stories Scary Case Studies
    Biology, Pharmacology & Drugs 101
  • Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

RCs 4,4-Dimethylaminorex (4,5-dihydro-4-methyl-5-(4-methylphenyl)-2-Oxazolamine)

I've heard a lot of people doubting this is really an aminorex analogue due to the more serotonin heavy high and shorter duration, so figured it would be worth reminding people that what 4-Methylaminorex is to Meth, 4,4-DMAR (which we could also call 4-Methyl-4-MAR) is to 4-Methylmethamphetamine, reports on 4-MMA describe it as very serotonin heavy and shorter lasting than Meth, with a higher dosage - all these things also seem to be true of 4,4-DMAR when compared to 4-MAR. Also 4-Flouro-4MAR has previously been synthesized, and is the closest thing structurally we can compare this to, and it was also reported to be shorter lasting and more serotonergic/less dopaminergic than 4-MAR. I personally think this is likely to be the real thing, particularly since customs and such have found NMR confirmed 4,4-DMAR across Europe already - but we still need to approach this with caution as just because there's real stuff about doesn't mean the stuff you personally are getting is the real thing.

It's also worth bearing in mind since while 4-MAR is regarded as potentially non-neurotoxic or at least less so than Meth and MDMA, this might not be true for 4,4-DMAR when we consider that 4-MMA seems to produce long-term negative psychological effects resembling neurotoxicity, which are unsurprising given it's close relation to known neurotoxic amphetamines like 4-Bromoamphetamine etc.

I managed to get my hands on 100mg of the stuff yesterday, and tried 10-15mg vaporised at the end of a 130mg 6-APB comedown. (Please don't try this, we know other aminorex analogues are very heavy on the heart, and 6-APB is too, so this could be quite dangerous, I did this as a result of drug-induced silly thinking) - felt a wave of calmness come over me and the depressing thoughts of the 6-APB comedown were relieved, I was brought into a nice relaxed state, felt very little stimulation, and then quickly began to feel very cold. Didn't take any more as I want to see what this stuff is like on its own. Also don't know if I'll be using vaporisation as I can't find any other reports on this ROA and am not sure how effective it is when compared to other ROAs. Was able to sleep just ~3 hours after vaping the stuff (though it was a little tricky) but think that was due to the low dose.

Edit with opinions after trying a larger dose:

Turns out I only got about 50-60mg total to begin with because afterwards I weighed what I had left and I had 40mg. I've now eaten the empty wrap (since it had some stuff to it) + 10mg, snorted 20mg (ow! the pain is pretty bad, not quite as bad as 2C-x but this stuff can't be good for the nose), and vaped 10mg, though the pipe still has a little left in it. Not gonna try report since live reports are silly and not allowed here but I can say it's nice, reminds me of 4-MMC but more mentally stimulating, less physically stimulating. Higher dose would have been nice, but I supplemented with a low dose of a mild stimulant and it's going well, music is heavenly. Less mongy than I was expecting, quite stimulating, but the reduced serotonergic effects may be due to me having consumed 6-APB + this yesterday. Vaping on the peak resulted in a rush stronger than MDMA but the rush itself was short-lived and then faded back into additional stimulation. Heart rate and BP are only slightly elevated, and come up was a little rough, and I'm sweating a little, overall fairly clean at this dose as far as side effects go.

Think this stuff is worthwhile. 60-70mg oral is probably an ideal dose, but since redosing seems to work fine and this stuff is new I'd recommend starting lower (30mg~) and then redosing if necessary.
 
Last edited:
I absolutely think this is perfect. I predicted a shorter duration of action, via analogy to 4-MMC. The duration of action was a central problem in 4-MAR. The added serotonergic effects are kind of like a bonus. Additionally, the fact that its dosage is higher makes it a bit easier to avoid overdosing.

Hallelujah - I was deeply obsessed with 4MAR for 6 months in the past year. So curious...
 
I reiterate: be very careful with regular use of this. As an aminorex analogue, some people may be susceptible to seriously bad pulmonary hypertension.

The epidemic of aminorex pulmonary hypertension taught several important lessons. First, substances taken by mouth can produce pulmonary vascular lesions that are confined to the small muscular arteries and arterioles. Second, only 2% of those who ingested aminorex developed primary pulmonary hypertension, suggesting genetic predisposition. Third, in keeping with this concept of genetic predisposition was the inability to elicit pulmonary hypertension by the feeding of aminorex to experimental animals selected at random. Fourth, although aminorex-induced pulmonary hypertension in humans often progressed after the drug was stopped, it did regress in 12 of 20 patients followed for >17 years; ie, the pulmonary vascular disease in these patients appeared to be reversible. Although aminorex was identified as the principal cause of the epidemic, noteworthy with respect to contemporary concerns about fen/phen-induced pulmonary hypertension was a significant association between the use of chlorphentermine, which is closely related clinically to the phentermine of fen/phen (see below), and pulmonary hypertension.
Click to expand...
 
is this a worry if people treat this drug like they should treat entactogens, ie seasonally with once a month use sporadically?

ebola
 
I don't think ROA matters, the issue is the presence of the compound in the blood. Infrequent use will certainly work in your favour, as well as looking for a family history of heart disease or mysterious deaths from stimulant use.

However, it is important to note that this seems to be genetically-linked, in that certain individuals will almost certainly exhibit symptoms after some time of use, whereas others can use somewhat more frequently without worry. Until easy and accurate genetic screening is accessible to everyone, the major issue is that one cannot tell - just guess based on careful genealogical searching whether they will have the mutation.

At the very least, if you use this drug more than once or twice, it makes sense to have a physical examination (heart sounds and blood pressure and the like) on a regular basis until you are certain you're not going to get burned. And if you notice you have serious vasoconstrictive / hypertensive (high blood pressure) symptoms, stop taking it immediately. The effects do seem to be reversible with continual abstinence from aminorex derivatives.
 
foolsgold said:
right hopefully im getting 500mg of this very soon so what is the starting dose for it please

scratch that ill follow jesusgreens dosing
Click to expand...

I've never tried this but people I know are loving it
From what I hear there are possibly different racemates (cis/trans) with different doses so start low like jesusgreen says - and go easy: apparently it's so nice some are wanting to redose a lot; but it's a new chem : until you know your response it worth setting limits and seeing how you react to it
 
Last edited:
i tried it wednesday found it next to useless and very dangerous got the start of serotonin syndrome at very low doses the twitching and jerking awake was not nice wont be repeating the experience also now a bit bothered by the fact its friday night in im still feeling it when i have a coffee i get shudders got 3g of mpa coming in the morning and wondering now if the will be any interaction with that ?
 
WARNING - Serotoni

Yes, Serotoni is a branded chemical and IIRC that isn't allowed, but it also has a known chemical formula.

This is a warning given on the UKChemicalResearch forum.

Source: http://www.ukchemicalresearch.org/Thread-SEROTONI-WARNING-PLEASE-READ

Blodwyn said:
I have been passed this information from a personal source who has grave concerns about serotoni. It is been indicated that there is alot of this substance in the RC world at present and certain vendors are getting rid of it as fast as they can, dont be surprised if this starts popping up in illegal pills or even branded products. I have always had grave concerns about this product the details below should indicate why.

The substance pMe-4MAR and the main danger with it as with many others lies both with heavy dosing, but in particular taking other substances even 1-2 days after use of it.

Without question pMe 4 MAR is going to be something that makes serotonin and dopamine rapidly evacuate neurones, bear in mind similarities with mephedrone (oxygen atom on benzilic carbon atom, secondary amine with amine function two carbons removed from thearoimatic nucleus and the p-methyl group which allows it to interact with the SERT as well as the DAT.

Combine this with the extremely long half life of the parent molecule (4 MAR) and it's still going to be doing it's stuff as a potent reuptake inhibitor 24 hours after taking it even if the noticable subjective effects of this have worn off (4MAR has a period of activity of about 16 hours & it doesn't have a p-methyl group slowing down it's metabolic degredation rate).

Its still going to be present in the body up to a day later so if for example you were to take a dose of a compound that causes massive serotonin (& to a lesser degree dopamine) efflux, like 5-EAPB, or MDAI etc. Then you've got massive amounts of 5HT being pumped into the synapses and the SERT is essentially paralysed by the p-Me 4-MAR; also consider that some RCs and drugs are are going to be competetive inhibitors of MAO (like aMT, amphetamine etc). So what you have are the conditions for massive, way over the top, serotonogic activity.

That fits reports of people, after taking other substances 1-2 days after taking p-me-4MAR, being disorientated, having an increasing core temp are being caused by huge fluxes in the serotonogic pathways that regulate how much & which bits of sensory imput are directed around the brain to appropriate areas.

The brain can't pick out the bits that are relevant for survival in a consensus reality. Add to that hyperthermia will also mess around with the autonomic mechanisms (think of the confusion of heatstroke).

All in all, taking substances like 5-EAPB or aMT or MDAI and or anything similar within about 3-4 half lives of taking p-Me 4-MAR is going to flood the brain with serotonin and in a very dangerous way.

Please, please, please anyone that has a sample of this or who has purchased this read this information and do not be tempted with large doses or combining this with any other chemical/drug, legal or illegal.
Click to expand...
 
Yep, I got a sample of this and gave myself SS. The report is up on UKCR and has been for some time now. The circumstances were asking for trouble, however this drug is very unforgiving. It's not that great at low doses and is very dangerous in high ones. I think the name is a little misleading too, as people will be expecting a huge sert dump, but in fact it starts out very speedy and it's unsurprising that there have been repeated issues with individuals redosing. I won't be going near this one again for obvious reasons.
 
I took nearly 200mg of it (redosed multiple times) and had no unwanted side effects; in fact it was veerryy good, but next time I won´t redose and will only take one big dose and finish my sample.
Anyone here tried the rectal ROA?
It seems that many people here are talking about different substances. My "4-DMAR" (that´s what it says on the baggy, but the vendor sold it as 4,4´-DMAR) is not that speedy at all, actually I was sitting for hours on my chair and was listening to music without the need to move. Nearly no dopamine-effects were felt, but mostly serotonergic ones. I liked it very much. But of course everyone should start low and avoid redosing.
 
Last edited:
etreff: ***Alert*** Deaths in Hungary associated with 4-methylaminorex, p-methyl derivative

Dear colleagues,

This alert concerns: 4-methylaminorex, p-methyl derivative

We have received reports via the Europol network and the Hungarian Focal Point that there have been 8 fatal cases associated with this substance in Hungary. The Hungarian National Focal Point adds:

"In all of the cases 4-methylaminorex, para-methyl derivative has been identified in the biological samples. However, in the majority of the cases there were other substances detected in the bodies as well, such as alpha-PVP, alprazolam, mephedrone. The first cases were reported in June 2013. The reported 8 cases were detected in 5 different counties of the country. The appearance of the substance was powder in the first cases then later tablets (pink and green heart shaped and playboy shaped tablets).

In all of the cases the criminal procedure is in process the forensic medical reports have not been not concluded yet therefore we have no confirmed information on the role of 4-methylaminorex, para-methyl derivative in the deaths."

This substance was first notified by the Netherlands in December 2012. Since then, seizures have also been reported via the EWS in Finland, Hungary and Denmark in powder or tablet form. Tablets arriving in Finland had been posted from the United Kingdom.

Other names for this substance are 4-methyl-euphoria, 4-methyl-U4Euh, 4-M-4-MAR, 4,4'-DMAR and 'Serotoni'.

As the name suggests, it is a derivative of 4-methylaminorex (‘U4Euh’, ‘Euphoria’), which has been reported to be a CNS stimulant and possess anorectic effects similar to amphetamine. The parent drug, aminorex, was once an authorised medicine used as an anorectic agent but was withdrawn in 1972 as it was shown to cause pulmonary hypertension in a significant number of cases (2%).

From the literature, there is one death and a case series of three cases (all related) that associate 4-methylaminorex (production and use) with pulmonary hypertension [1, 2]. All these cases were from the US.
Click to expand...

From the EU Early Warning System
 
Sufo said:
Yep, I got a sample of this and gave myself SS. The report is up on UKCR and has been for some time now. The circumstances were asking for trouble, however this drug is very unforgiving. It's not that great at low doses and is very dangerous in high ones. I think the name is a little misleading too, as people will be expecting a huge sert dump, but in fact it starts out very speedy and it's unsurprising that there have been repeated issues with individuals redosing. I won't be going near this one again for obvious reasons.
Click to expand...
To paint a true picture though you should post your trip report, cause you stated that (Friday to Saturday afternoon had consisted of a binge on alcohol and a popular triple-reuptake inhibitor, the in vivo metabolite of which has a significantly longer half life, and could have played some role in the final outcome) and you dosed 360mg over 4-5hrs. People should give a full report on what my have caused any potential issues. Far to many people blame the chemical, im not saying that this chemical is safe, that i dont know but if you mix chemicals, take high doses, dont maintain your general health pre, during and post research and dont get adequate rest all of these will have an impact on the end result.

Just want to state this is not aimed at you Sufo(apart from posting your trip report)we all make mistakes, its just a a general view, we are dealing with potentially dangerous substances, we should all treat them with respect and that means maintaining and preapring your body for research. I am in know way stating that this chemical is safe or encouraging use im just saying the whole story needs to come out when members are reporting issues.

Also can people state whether they purchased it from the Uk or Abroad, since there seems to be varying potency.
 
Last edited:
foolsgold said:
mine was a lot more than an unpleasant reaction the twitching dizziness sickness well being sick scared me and that was at low doses
Click to expand...
Foolsgold you should give a detailed report of what happened. Im not saying in your case but some people dont mention the whole story. They have had no sleep the night before, had several cans of beer throughout the day, not eaten, not fully hydrated. Taken another chemical prior to their research, they are in poor general health but if they have a negative reaction they automatically blame the chemical and neglect the impact of their lifestyle has had on the end result.
 
You must log in or register to reply here.
Top