The Big & Dandy 25I-NBOMe Thread (2nd edition)

[celestica]

I'd advise against that tbh, both MDMA and 25x-NBOMes can produce a nauseating comeup, and with the MDMA push I could see how the body load of an NBOMe could become extraordinarily unpleasant. But if you feel comfortable w/ MDMA then go for it.

So I have a question -- if I left some NBOMe blotter out, exposed to air and possibly sunlight, for a couple days, should they still be good?

 

[porkstock]

i've read most of the thread, but maybe i missed it...
has anyone tried 25-i-nbome + 25-c-nbome? in equal amounts?

there are these 25i + 25c blotters, with 1.5 mg each. that seems like a large dose of either substance alone, so a whopping combination dose.

it's my understanding that 25c feels more potent? so ideally, this mixture would reflect that and be maybe 65% 25i, 35% 25c, for example.
or better yet, they would be on separate blotters!

for someone who has not tried an -nbome, and only had access to this combination...i was thinking that maybe 750 ug of each might be a good starting dose (to actually trip and not just get a tease)
should i be more cautious and try 500 ug each? even less?? obviously it would be best to try each chemical solo first. that has always been a rule that i followed, and i have only combined psychedelics once or twice.

you guys will probably tell me that these doses are too high. what's a proper starting dose of 25i alone? 25c?

i'm sorry, i know these types of questions are not encouraged, but it seems to be in the name of harm reduction...

two people have tried these blotters (buccally) - one took 750 ug each at first, then 1.5 mg each on the 2nd trip. other guy started with 1.5 mg each and had a good, but "easy" trip.
i think that maybe they aren't absorbing the whole dose. they were dissolved (complexed?!) in propylene glycol and then in ethanol and laid on blotter.

 

[dc710]

^ I wouldn't advise this. I definitely read one report on here I think, where someone had done this and experienced far greater vasoconstriction and nasty side effects than either substance on its own.

 

[Ekstasis-//7]

^^Yes the individual who combined 25C and 25I reported swelling limbs and really nasty sounding vasoconstriction. I too would advise against this mix and be careful when combining 25x-NBOMe compounds with other phenethylamines. Some kind of vasodilator kept on hand would be a good idea in case of emergency. Maybe glyceryl trinitrate which I believe is easily available to individulas. Be careful to check what dosages are recommended!

---> Where would an individual obtain a small and cheap ammount of the cyclic sugar: Hydroxypropyl Beta Cyclodextrin from?

 

[klondike_bar]

it's my understanding that 25c feels more potent? so ideally, this mixture would reflect that and be maybe 65% 25i, 35% 25c, for example.
or better yet, they would be on separate blotters!

what's a proper starting dose of 25i alone? 25c?

they were dissolved (complexed?!) in propylene glycol and then in ethanol and laid on blotter.

1) 25C IS more potent.

2) 25C dosage is about 750ug for most people. 25I dosage is about 1000-1500ug for most people. combining these would combine effects, so its not like taking 2*1 dose magically makes 1 dose, it will make 2 full doses, and will be very strong, as these have a big D/R curve

3) not sure why propylene glycol was used. ethanol is a fine carrier for dissolving on blotter. and complexing uses HPBCD sugars.

 

[zn13bt]

Yeah, don't combine 25C with 25I. The one time I tried it was with 300ug 25C and 500ug 25I, and I got shooting pains in my joints and muscles, and the palms of my hands and soles of my feet turned purplish-red and became very cold. The vasoconstriction was much worse than I would've gotten on 800ug of either substance alone. And the trip itself wasn't that great either, only a +2 and nothing interesting happened. I suspect combining other NBOMes would have similar issues.

 

[porkstock]

^ I wouldn't advise this. I definitely read one report on here I think, where someone had done this and experienced far greater vasoconstriction and nasty side effects than either substance on its own.

wonder what the ROA and the doses were...

Yeah, don't combine 25C with 25I. The one time I tried it was with 300ug 25C and 500ug 25I, and I got shooting pains in my joints and muscles, and the palms of my hands and soles of my feet turned purplish-red and became very cold. The vasoconstriction was much worse than I would've gotten on 800ug of either substance alone. And the trip itself wasn't that great either, only a +2 and nothing interesting happened. I suspect combining other NBOMes would have similar issues.

was this nasally, or buccal/sublingual?


the three people that have tried these exact blotters i have, didn't report any vasoconstriction or anything like that.

i'll probably start with 500 ug of each, rather than the 750 ug of each that was recommended by the maker and users of these blotters

 

[zn13bt]

was this nasally, or buccal/sublingual?

This was buccal with a blotter I made myself.

the three people that have tried these exact blotters i have, didn't report any vasoconstriction or anything like that.

i'll probably start with 500 ug of each, rather than the 750 ug of each that was recommended by the maker and users of these blotters

I tend to be more sensitive to NBOMes than others posting here, so that may have been a factor. It's a good idea to start out low and look out for any signs of vasoconstriction before increasing the dose.

 

[stirk]

Hello, everyone. I want you to all know that I have read a lot of this thread. A lot. But I have a question on a subject that I haven't seen discussed. You see, I have an amount of near pure HCL powder. The thing is, I do not feel safe working with such small amounts of potent powder. I realize that the main course of action for individuals when presented with this problem has been to use volumetric dosing. I, however, wish to keep everything dry for reasons that need not be discussed. I wish to create a mixture of 25i-nbome HCL and a harmless(nontoxic) filler powder. This way I can safely measure out an amount of, say, 20-30 mg of powder on a scale. Now, my diemna is how to go about doing this safely and without creating hot spots. What sort of powder could I use in this mixture? How can I make sure to evenly distribute the 25i in this mixture?
I realize these are basic and important chemistry questions and that is why I ask bluelight. I have trust in the thought of this board.
peace

 

[Mela]

Now, my diemna is how to go about doing this safely and without creating hot spots. What sort of powder could I use in this mixture? How can I make sure to evenly distribute the 25i in this mixture?

Use an excipient which flows freely - such as lactose (glucose is not ideal for a number of reasons). Perform gradual dilutions (i.e., add the lactose in progressive steps). Mix thoroughly at every dilution and for a long time using an appropriate implement and method (e.g., spinning a spatula in [doubled] snap-bag, close bag, loosen powder mix, roll around to clear corners, and then compress powder, loosen powder, then start again). I did something similar with 4HO-MET, and it worked fine (i.e., on use doses give consistent effects).

You will only know how well you mixed on use. Such dry mixing is the norm in pharmaceutical formulations, but they use quantitative assaying to ensure the doses are within expected range (~90-110%). You will only know how homogeneous the formulation is through subjective effects. I do think you'll need to be extra-careful with the NBOMEs (and would suggest aqueous dilution the by-far safest option) - a compound like HO-MET is likely to be quite forgiving if you F* it up.

 

[freedstar]

Be careful with combining this.

Remember it's not just "this + that" more like "this x that". Sorta how a low dose of benzos plus alcohol has the potential to get you blackout drunk pretty quickly.

 

[foolsgold]

well i did 2 tuesday n nothing just no luck at all with these chem

 

[Transform]

Creating powder mixtures without hotspots is very challenging. The particles must be the same size or settling can occur easily.

If complexing works then your best bet would be to create a complexed solution then re-dry it.

 

[Expect]

I combined 500ug of 25C-NBOMe with 1.2mg of 25I(complexed, sublingual).


I felt no negative side effects and had a pleasant trip, but I've never gotten vasoconstriction at any dosage of either drug

 

[Ekstasis-//7]

Originally posted by Mela
Use an excipient which flows freely -such as lactose (glucose is not ideal for a number of reasons)

Is powdered sucrose okay instead of lactose for the excipient after all they have the same molecular formular?

For what reasons is glucose not a good excipient?

Thanks

 

[Mela]

Is powdered sucrose okay instead of lactose for the excipient after all they have the same molecular formular?

For what reasons is glucose not a good excipient?

Thanks

Lactose (alpha/beta forms) is one of the sugars with a very low hygroscopic nature (and high 'flowability'). Hence it's common use (along with cost & inertness) in formulation. Glucose by comparison is relatively hygroscopic (and thus pulls moisture from environment).

ABE: Not sure about sucrose, but can't see that it would have any benefits over lactose.

 

[Jinux]

I've found that alcohol has a HUGE dampening effect on this chemical. I've tried it a total of 4 times at both 1 and 2 mg.

1st dose: 1mg sublingual. Went down the pub to listen to a local reggae band. It was an excellent night but I noticed no visuals at all. There was sliiiight enhancing of lights but nothing else. Body high was a slight antsy feeling as if I was constantly coming up. This wore off after I finished my first pint and never returned.

2nd dose: 2mg buccal. I was at a party and drank again. I noticed the antsy feeling again which subsided after a little while. I was standing and dancing for most of this trip but I did notice that music was enhanced slightly and I had a small amount of visuals when I looked at a patterned rug on the floor. Body high was very close to a soft roll, which I've heard 2C-I itself tends to feel like (no experience).

3rd dose: 1mg buccal. I went out to a local bar on my own and drank here too. The antsy feeling stayed with me most of the night but it progressed in to more of a jittery over-stimulation. It wasn't pushy, just I would occasionally have to stretch out or shudder. I also had to sip my drink quickly else I would end up shaking the glass too much to be able to drink from it. Music was very nice, though the DJ was talented irregardless of my state. There were no noticeable visuals at all until I went to the toilet and looked at my self in great detail in the mirror, I had some slight blurring of the edges of my face and hands, and my skin seemed a lot more intricate and HD than normal.

4th dose: 2mg buccal. This time I was at home on my own just chilling at the computer listening to tunes. I got the same antsy feeling but this soon turned in to the almost-roll feeling I mentioned earlier. This was on top of the jittery over-stimulation feel I also mentioned. It felt very nice actually. Music sounded amazing, and the visuals. Oh wow the visuals. Everything was bleeding with huge blurs. The only way I can describe it was like being underwater in a rainbow. Liquid colours encompassing me.

 

[any major dude]

Regarding dry powder mixtures containing 25x

This is really not a good idea. Pharmaceutical companies go to great lengths & expense to make sure they have uniform mixtures, you do not have this capacity at your house. Volumetric measurement may be slightly inconvenient at times, but that's a lot better than accidentally doing several mgs of 25x when you'd intended on taking at most 1 or 2. And that's not the worst that could happen. Bluelight is a harm reduction board, not a convenience facilitation board.
One potential thing one could do is use a carrier like mannitol for insufflation & drop the liquid containing 25x onto it in individual doses. The latter bit is very important, otherwise you'll end up with hot spots. There's no reason to sacrifice safety for expediency here.

 

[Mela]

This is really not a good idea. Pharmaceutical companies go to great lengths & expense to make sure they have uniform mixtures, you do not have this capacity at your house.

Well, I agree with almost everything you say. However, a home kenwood mixer with a shear blade would perform the same process as found in pharm for dry blending. Smaller batches are even made in bottles on a tumbler. Obviously not gonna give too much personal info, but - been there, done that. Of course, the benefits of the pharm process is the ability to actually test blend homogeneity quantitatively (but, tbh, if done properly batches rarely fail on assay - and properly usually means mixing for around 1 hour).

I think the issue is that people are going to do dry mixing whether it be the safest option or not (hence why it keeps popping up). In fact, from what I hear such diluted dry mixes are even being sold (hence why some might think to go that route). Therefore I would think at least highlighting potential problems (hotspots and granular separation - see Transform's post) and most effective methods (as I've tried - slow, gradual, thorough, and prolonged) is harm reduction. At least with the clear caveat that aqueous dilution is the safest route (but as I'm sure you know, even some people find that rather challenging!).

Still, I know I won't be going the dry mix route for any NBOME I might have. But If I were I would use the process I've outlined. If I was doing it for larger batches I would probably use a bottle-tumbler method. The main point is that gradual dilutions and careful thorough mixing with a good excipient will ensure that hotspots will be minimal. If people are sloppy they are likely to f* up via either route (dry or aqueous).

ABE: I would also say that the dry mixing method is not even near to most convenient or practical - think it's worth pointing this out. Throwing a few dozen mgs of active in some solvent is actually the most convenient and practical approach. For instance, for the 4HO-MET batch, it took me four days to complete the mixing (working an hour or so at a time for each dilution)!

 

[Ekstasis-//7]

^^ thanks for the help. I just thought I'd let people know I found some interesting info on a site that compares the properties of different sugars. Although sucrose is listed as used as a binding agent it is also listed as a humectant! (water absorbing!!). One site said it can only absorb a maximum of 1% moisture but I think I'd rather not take my chances! The info I read on lactose seemed to look better. Lactose was listed as a good flow agent even in humid environments and having a low hygroscopic nature as well as absorbing colour well. It seems the better choice for an excipient. I know home brew shops sell lactose powder.

One question regarding mixing... I am thinking it maybe better to mix and keep in folded gloss magazine paper. I am just worried about mixing in a bag as I've seen some compounds such as etizolam seem to stick to the bag like some kind of electrostatic force is going on.