• 🇳🇿 🇲🇲 🇯🇵 🇨🇳 🇦🇺 🇦🇶 🇮🇳
    Australian & Asian
    Drug Discussion

    Welcome Guest!
    Posting Rules Bluelight Rules
  • AADD Moderators: andyturbo

Codeine and CWE Megathread - The long awaited!

Status
Not open for further replies.
hmm i was hoping the apap would be a little less soluble than that. sometimes I only leave it in the freezer 25 mins. I suppose that should be getting it down to around 10 degrees C. I use 100mL of water. I use cold water from the tap so Id assume that would be colder than 20 degrees C to start with cuz I use chemists own pain tablets & the just dissolve themselfs so ya dont need warm water to help with that
Im probably left with about 1g. not to much to worry about I suppose. I did get a liver test done about a year ago & the dr said that mine was more healthier than his lol after all my binge drinking & cwe's

I hate how the save button doesnt work sometimes when ya go to edit a post & ya have to re log back into before it works again. has anyone noticed that?
 
Last edited:
" Originally Posted by footscrazy
The solubility of paracetamol is 9.44mg per ml of water at 10 degrees celcius. So for a 40 tab extraction, if you're using the common method of using 2mls water per pill, you've got 80mls of water. At 9.44mg paracetamol dissolving per ml of water, you'd expect to be left with 755.2mg of dissolved paracetamol in your final extraction. That's just about 1 and a half tablets, which is well within the recommended dosing of paracetamol. Any amount of paracetamol still does work your liver, and it is wise to give it a break, but that is a fairly safe level. Of course this doesn't include any undissolved paracetamol coming through the filter, which means it is important to try and get your cdub as clear as possible.

Source here (with paracetamol solubility in 0, 5, 10, 15, 20 and 25 degrees celcius water too)

Solubility of ibuprofen in water at 25 degrees ceclius is <1mg/ml."

I think it is worth mentioning that those figures are only a rough guide and would vary greatly.

A bigger concern than liver toxicity at that dose is damage to the gastrointestinal tract. Ibuprofen and NSAIDs in general are a leading cause of gastric and duodenal ulcers in Australia. We are not talking about chronic overdosing either (well technically we are talking about over dose because these drugs shouldn't be taken in the long term), ulcers and damage happen at regular doses. The lining of the stomach is protected from it own digestive juices, NSAID's temporarily inhibit (at the recommended dose) the stomachs ability to secrete the protective allowing the hydrochloric acid in the stomach to eat away at the stomach lining. Ibuprofen specifically has been shown to be directly caustic to the mucosal lining of the intestine.

If we all start doing CWEs on plain ibuprofen tablets (cheap supermarket pills), we could easily get a good visual (and weight if you have mg scales) idea of quantity of crap that makes it through our CWEs. Just filter the CWE to crystal clarity and let the extract evaporate recrystallising the ibuprofen or paracetamol that made it through the CWE. If we are careful and thorough in our written descriptions our CWE attempts we could all post and compare pictures and weights etc. We could have the best possible procedure down in no time and we'd know with more confidence the safety and risks of CWE. If it turns out there are water soluble fillers we could probably deduce the amounts with a mg scale and the known weight of each filler in each pill.

It'd be easy and worth while if more than a few people did it.
 
Last edited:
I realise I was talking about ibuprofen but I don't want to imply that paracetamol even at doses of less than a gram per day are healhy in the long term.
"Paracetamol hepatotoxicity is, by far, the most common cause of acute liver failure in both the United States and the United Kingdom."

In June 2009, a U. S. Food and Drug Administration (FDA) advisory committee recommended that new restrictions should be placed on paracetamol usage in the United States to help protect people from the potential toxic effects. The maximum dosage at any given time would be decreased from 1000 mg to 650 mg, while combinations of paracetamol and narcotic analgesics would be prohibited. Committee members were particularly concerned by the fact that the present maximum dosages of paracetamol had been shown to produce alterations in hepatic function.[44] On January 13, 2011, the FDA asked manufacturers of prescription combination products containing paracetamol to limit the amount of paracetamol to no more than 325 mg per tablet or capsule and began requiring manufacturers to update the labels of these products to warn of the potential risk for severe liver damage.[45][46][47][48] Manufacturers will have three years to limit the amount of paracetamol in their prescription drug products to 325 mg per dosage unit.[46][48] The FDA also is requiring manufacturers to update labels of all prescription combination paracetamol products to warn of the potential risk for severe liver injury.[45][46][48]
from the wiki paracetamol page.
 
Last edited:
Everyone who does regular CWE should really just get an occasional blood test and check for liver function. I did it recently as part of a detox thing I was doing (that mum finally got me and my brother to do), and it showed up all clear. I wouldnt have voluntarily gone to get blood tests or go to the doctor so I understand people not wanting to do this shit either... but it feels good to put your mind at ease. Even if you think you arent worrying about it when you find out all is (hopefully) good you realise that it really was constantly in the back of your head.... as we know it can sometimes be a little concerning when youre 2x extracting 40 + apap pills.

And if it absolutely isnt something thats worrying you even a little.... well then it fucking should be! Just from a common sense perspective.
 
pinkanga
Are you using paracetamol/codeine tabs (CWE up to 40 apap500mg/codeine~10mg, twice/day?)? If you are using paracetamol exclusively and that many tabs then you would think that your technique is working if you liver is not showing up on tests. Assuming you use every day for a few months?

I was always too scared to use the paracetamol/codeine pills. To me it felt like one mistake with those pills and its all over.

I agree that seeing a doctor and getting checked out is worthwhile if your into CWE.

One thing that is important to realise is that the a lot of the main issue with ibuprofen show up on liver or kidney markers i.e. the cardiovascular (cardiac arrest, stroke, hypertension, palpitation) and gastrointestinal tract corrosion:(. A lot of people take there CWE on an empty stomach and it has just dawned on me that is the exact opposite of the dosing directions for ibuprofen i.e. take with food, never on an empty stomach . Also the codeine helps us to ignore the gnawing, stomach digesting feeling that comes with moderate ibuprofen doses on an empty stomach. All of these toxicity issues have potentially lethal outcomes.

I also wanted to remind or make people aware that some NSAIDs have been proven to increase the risk of heart attack my amazing figures, something like 50% increase in the change of heart attack due to even short term use. SOme NSAIDs have been banned because they are suspected of KILLING obscene amounts of people by cardiac arrest.

"The present results indicate there is no apparent safe therapeutic window for NSAIDs in patients with prior [heart attack], and challenge the current recommendations of low-dose and short-term use of NSAIDs as being safe," said study author Dr. Anne-Marie Schjerning Olsen, a research fellow at Copenhagen University in Denmark.

Read more: http://www.philly.com/philly/health/topics/132452093.html#ixzz1jM3NuRQn


Danish researchers analyzed nationwide records of almost 84,000 heart attack survivors and found that those who used certain non-steroidal anti-inflammatory drugs (NSAID) for one week faced a 45 percent heightened risk of another heart attack. Three months' use raised the risk to 55 percent.

Read more: http://www.philly.com/philly/health/topics/132452093.html#ixzz1jM3NuRQn
 
Hey, def not twice a day, or even every day. I meant Ill do a 2nd extraction on the 40 pill gunk to maximise the amount of extracted codeine. Sometimes Im too lazy.

Couple times a week. Yeah apap/paracetamol.
 
ah ok, that explains it.

If your only doing it a couple times a week you wouldn't expect detectable damage unless you were really doing it wrong.
 
what kind of paper filter do ppl ues? ive been using coffee filters from the supermarket, but they leave a foul taste. ive looked around and everyone stocks the same thing. now im thinking i might just get proper lab paper filters. will they work ok? are all filters created equal? browsing ebay atm.
 
I use 4-ply tissues; I found one brand that doesn't break and filters it to acceptable level. I first pour some water on it - it washes away some of the paper taste
 
I use two coffee filters i.e. one inside of the other to provide double thickness.

I found it almost impossible to use a single filter and not break it, ruining the extraction and lengthening the amount of time the ibuprofen was exposed to the cold water.

The filter used in lab ware are of course difficult to use with out a buchner funnel type set up that a vacuum can be applied to.

The beauty of double up and folded properly (crimped edge folded to strengthen the seal) coffee filters is that they can be squeezed (very carefully). By using the right water volume it is possible to neatly and securely seal the extraction inside the coffee filters by twisting the open end of the cone closed.

I think the amount of time the crushed pills are exposed to water is a crucial factor effecting amount of ibuprofen dissolved. The others being water temp/purity and of course filter quality and integrity. I always try to get through the process of adding powder to icy water --> quickly mixing --> begin quickly filtering with lite pressure in seconds.

To save time I use a metal pot in the freezer. To get ice cold water I quickly strained ice water water from a metal pot in the freezer that had gotten cold enough to grow large ice crystals and leave a few hundred mls to extract with. I think pre filtering with a T-shirt (etc) is a good idea because it makes the final filtration much easier but I left it out because it increases the amount of time the ibuprofen has to dissolve.

Ibuprofen has a peppery hot taste/effect on the tongue. I used the above method for over a year and it consistently cut down on a lot of the peppery taste but did not eliminate it. A lot of the intensity of the usual gut problems associated with ibuprofen were diminished as well but not all by a long shot.

edit:
I should add that I only ever performed the extraction on 8 pills per filter i.e. to filter ~80 tablets I would have to carry out 10 extractions.
 
Last edited:
It's not too bad, used to take about 20 mins to do 80 tabs.

What do you do differently that might make it a bit easier? Are there any steps you'd leave out or add?
 
Last edited:
Takes me 30 seconds to complete a CWE thesedays from the time I put in the pills in the water til i drink it :) Comes out fairly well too.
 
Drop pills in a glass add 2ml water for each pill (can place in fridge for 30 mins if u really want to) then wet a shirt placed over a collecting bowl. Pour through whilst mixing and then make a ball (I usually make a sausage out of it, i find its much better to squeeze the actives out of it. Add same amount of cordial and enjoy. Doesnt take long at all and filters well. Look up ibu/para solubility and do the maths.
 
Was picking up some antibiotics, sick as a dog at the moment.... it's been a while since I last used codeine.... (months).

Picked up a 40 pack of 10/500 tablets and have the lot crushed and chilling in the freezer at the moment.

I miss the warm fuzzy euphoria...
 
Not sure how some of you guys drink the Paracetamol ones:S They taste horrible even mixed with cordial. Makes me gag bad just thinking of it. Do u chug it straight?
 
I only use paracetemol and not ibuprofen for my cwe's (or used to). (specifically I used to use panadeine extra.. )

It's a matter of chugging it and chasing with (usually a can of coke) which tends to fizz in your mouth. Yuck.

EDIT: Thanks Sustanon, now I'm sitting here staring at what appears to be 2 full mouthfuls of liquid which you've now made me well aware will taste like ARSE. :( hahaha
 
Last edited:
Haha add 50/50 cordial, makes it bearable usually with ibuprofen. With paracetamol man it still tastes super bitter and strong :(
 
Status
Not open for further replies.
Top