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Once a month MDMA use. Anyone notice long-term side effects?

hesitant_user

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Nov 22, 2011
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Hi everyone, I first tried MDMA about 10 months ago. My usage has averaged out to about once a month since then. After my first few times I began taking all the recommended precautions; anti-oxidants, drinking plenty of water, taking breaks if I'm dancing, using an SSRI (Prozac) after I return to baseline to (possibly) reduce neurotoxicity, as well as using 5-htp the week after to reduce hangover symptoms (I should note that my MDMA hangovers have been non-existent or extremely mild, even before I began to take these precautions). I told myself that I would reduce my use to no more than 3 or 4 times a year from now on, but I have two opportunities to do MDMA in the next two months, and I would really like to partake on both those occasions.

I don't use many other drugs, only weed on Fridays and Saturdays, and occasionally alcohol (1 - 3 times a month). Stopped smoking tobacco two months ago as well. I'm a pretty healthy person, although I could use more excercise haha.

I am looking for anecdotal reports from people who have been using or have used MDMA at this frequency, regarding any long-term side effects that you may or may not have experienced. So far I have not noticed any long term-effects, but I have noticed that after my last two experiences I caught nasty colds right after. I know MDMA is an immunosuppresent, and being in a sweaty-ass nightclub is the pefect environment for bugs to float around.

Thanks for any help :D
 
well ive been going at this rate for nearly a year now, and i dont notice any negatives,
I did in the beginning the comedowns were awful, but i eat certain foods to get around that now.

Its important if you know whether to weigh a decent 1 Dose and take that,
Or redose, which always gives me a comedown and its not as intense as first dose
 
Nope, none yet I feel usually back to full strength after about a week, after the 4th I feel like Its time :p
 
I did it for two years like this before it became hell. So I guess it depends on how long you wish to continue down the path. Most people mature out once the negatives outweigh the positives. It will eventually happen and each person is different. For some it could be 3 months and for other they can get away with it for a few years.
 
You'll be alright for a while, but don't expect to keep doing this for any more than half a year or so. Side effects will creep up on you in a way where you don't exactly notice it until your life is consumed by anxiety, depression and cognitive issues. You suddenly can't remember things, you start having a more pessimistic outlook on life, your balance is constantly slightly off, perception is slightly off, you begin feeling empty and useless, just generally 'in a funk', and all these symptoms slowly show themselves in very sneaky ways. You don't detect something one day and say "Oh, there's a side effect, I should stop using E now to prevent issues." No, no, it goes more like "I'm fine, I'm fine, I'm fine, I'm fine, OH MY GOD I'M SO NOT FINE I NEVER HAVE BEEN AND NEVER WILL BE AGAIN!!!!"

At least that's how it went for me. :)

Just be careful man!
 
Another awesome precaution to take is to get some kava kava extract and take like 200 mgs kavalactones because kava is an MAO-B inhibitor, which significantly reduces the neurotoxicity of MDMA. :) yay for less dead cells!!! :D
 
darksidesam.. what kind of foods do you eat to help with the comedowns? my comedowns aren't awful but I feel weird and sketchy the whole next day. i hate it :/
 
And to answer the original question... I did this for a while last school year (I don't even know if I'm remembering correctly lol) once every 3-5 weeks with occasional breaks. I'm not very observant about the effects because I've never felt totally normal even before I was doing m (anixety, depression, not diagnosed but I know somethings up) but I have noticed my short term memory is AWFUL. And I've started noticing this a lot in the last few months.

I still roll once every 2 months sometimes every month. I try not to but events pop up and it's so hard to say no for those occasions lol. Other than that I don't see any huge changes... I started getting 80s in math that I failed twice (last year and the year before) lol.
 
Hmm, so once a month is a bit too much eh? For those who notice short-term memory impairment what is it like? Would you be having a conversation with someone and then forget what was just said? Also some of you mentioned mood-related changes (anxiety, depression). How signifcant are these changes? I'm already slightly pessimistic at the moment, school is getting stressful. Maybe I'll put off another MDMA experience for now, I don't need to be more susceptible to stress or anxiety than I already am.
 
Hmm, so once a month is a bit too much eh? For those who notice short-term memory impairment what is it like? Would you be having a conversation with someone and then forget what was just said? Also some of you mentioned mood-related changes (anxiety, depression). How signifcant are these changes? I'm already slightly pessimistic at the moment, school is getting stressful. Maybe I'll put off another MDMA experience for now, I don't need to be more susceptible to stress or anxiety than I already am.

MDMA in any capacity will do absolutely NO good for your stress/anxiety/school situation. It will only throw you off more and more and more until you are abstinent for many months.

Short term memory loss is not being able to remember what you had for dinner the night before. Imagine the same kind of memory loss you get while being stoned on cannabis, but you're that way all the time, even when stone-cold sober. Not able to recall specifics from a conversation that was had not long ago. Watching a movie, and then not realizing until half way through that you already saw it a few months back. Walking into rooms and forgetting what you went in there for, then leaving the room, remembering, go back into the room, forget completely why you went in there at all, get distracted by something else, etc.. Coming into work on Monday and struggling to remember what you did on Friday. You literally feel like your brain just stops learning from time to time. Your recent past is very spotty, large gaps of time are just missing or hard to remember specifics about. You remember big events, large chunks of 'phases', but details and specifics about the recent past is nearly impossible to recall. I have never taken MDMA while going to school, so I have no idea how it would effect my learning and ability to study/remember/recall things. I'd imagine it would be awful!

The mood changes are most likely varied from person to person, but in general, you won't notice small changes in your overall mood and state of being until it actually hits you like a ton of bricks one day, and you have a mental break down. There will most likely be something that happens in your life that triggers a sad emotion in you, like a break up, death of a loved one, low scores in school, financial hardship, anything saddening, and you will become wayyy more sad than you normally would get, and then it all hits you and start to think things like "I'm helpless, I broke my brain, I'll never be happy again, life feels empty, there's nothing to live for," etc.. Then you just start to obsess over the fact that MDMA ruined you...

Again, at least this is how it went down for me. Your experience will be different.
 
MDMA in any capacity will do absolutely NO good for your stress/anxiety/school situation. It will only throw you off more and more and more until you are abstinent for many months.

Short term memory loss is not being able to remember what you had for dinner the night before. Imagine the same kind of memory loss you get while being stoned on cannabis, but you're that way all the time, even when stone-cold sober. Not able to recall specifics from a conversation that was had not long ago. Watching a movie, and then not realizing until half way through that you already saw it a few months back. Walking into rooms and forgetting what you went in there for, then leaving the room, remembering, go back into the room, forget completely why you went in there at all, get distracted by something else, etc.. Coming into work on Monday and struggling to remember what you did on Friday. You literally feel like your brain just stops learning from time to time. Your recent past is very spotty, large gaps of time are just missing or hard to remember specifics about. You remember big events, large chunks of 'phases', but details and specifics about the recent past is nearly impossible to recall. I have never taken MDMA while going to school, so I have no idea how it would effect my learning and ability to study/remember/recall things. I'd imagine it would be awful!

The mood changes are most likely varied from person to person, but in general, you won't notice small changes in your overall mood and state of being until it actually hits you like a ton of bricks one day, and you have a mental break down. There will most likely be something that happens in your life that triggers a sad emotion in you, like a break up, death of a loved one, low scores in school, financial hardship, anything saddening, and you will become wayyy more sad than you normally would get, and then it all hits you and start to think things like "I'm helpless, I broke my brain, I'll never be happy again, life feels empty, there's nothing to live for," etc.. Then you just start to obsess over the fact that MDMA ruined you...

Again, at least this is how it went down for me. Your experience will be different.

Luckily I haven't gotten to that point yet, in respects to both the short term-memory loss and changes in mood. I actually am better able to handle things now than I was before I used MDMA. I am in NO way saying that MDMA made me better able to cope, just that it hasn't done the opposite (yet). How often were you using M? And how are you doing now?
 
I recognize myself in your post, Seattle_Stranger. I started having my first experiences with rolling this summer, but with 6-APB instead of MDMA (but I think the side-effects will be similar). I've always had a crappy short-term memory (probably due to my ADHD) and also smoke weed on a daily basis, so I am familliar with forgetting things. But after this summer I have the feeling that my memory has gotten worse. I've used a lot of 6-APB in a +-5 week time-span and have been using it once a month since. I am doing a program to cut down on the weed, so that should fix things somewhat. But now I'm a little worried that this is permanent. Is there a chance that if I abstinate for a while things will turn back to normal?
 
I can definately relate to what Seattle is saying, but it never got bad for me, never affected my life in a negative way. I was getting warning signs that if I continued getting out of this world high like I was getting that I was going to destroy my brain. It took quite some time before I realized this at all (after dropping and snorting grams upon grams of crystal over half a year, a few times taking it multiple times over a week up to 4 out of 7 nights). Initially, I thought MDMA was a Godsend.

However, this all ended a year ago. Even after all this time away from it, the thought of rolling again is frightful after using it so much. I believe, based on how much MDMA I have done and how it has affected me that once a month is pushing it, but probably okay to do for a few years if you exercise daily, eat healthy, and absolutely never break the once per month rule straight from the start. Since I totally broke the once a month rule for a little while, didn't even know about it, using it once a month these days would make me FUCKING INSANE. If you abuse other drugs, or do not live an active and healthy lifestyle on a daily basis, or if you have ever in your life taken MDMA more than once per month in the past, then you should stick to once every 3/4 months to be safe. For someone who has used it extensively, once every 4 months is the absolute most I can do it carefree.

darkside really does have a great food list, not only for serotonin production - I have been paying attention to and refining my diet for years now and his list is basically the food I eat to be as lean and healthy as is possible for myself.
 
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Nope =D hardly got any side effects from using once a fortnight... infact was doing once a week for months and didn't get much of a come down or anything. got some minor brain zaps though, wouldnt recommend
 
I recognize myself in your post, Seattle_Stranger. I started having my first experiences with rolling this summer, but with 6-APB instead of MDMA (but I think the side-effects will be similar). I've always had a crappy short-term memory (probably due to my ADHD) and also smoke weed on a daily basis, so I am familliar with forgetting things. But after this summer I have the feeling that my memory has gotten worse. I've used a lot of 6-APB in a +-5 week time-span and have been using it once a month since. I am doing a program to cut down on the weed, so that should fix things somewhat. But now I'm a little worried that this is permanent. Is there a chance that if I abstinate for a while things will turn back to normal?
I'm happy to say that I can actually answer my own question :D I study Psychology and incidentally the subject we're covering right now is drugs (my favorite thusfar ;) ). According to the literature these symptoms will probably go away as your brain will sort of repair/recover itself (unless one really overdid it, which I don't think I did). Only downside is that it is going to take a few months for the brain to recover the damaged neurons. So I've decided to do two more rolls this year: on Christmas eve and new year. After that I'll give the gray lump a few months to recuperate. Once everything feels sort of back to normal I'll have a celebration pill/bump/stamp/whatever and keep myself to the once a month rule.
 
I'm happy to say that I can actually answer my own question :D I study Psychology and incidentally the subject we're covering right now is drugs (my favorite thusfar ;) ). According to the literature these symptoms will probably go away as your brain will sort of repair/recover itself (unless one really overdid it, which I don't think I did). Only downside is that it is going to take a few months for the brain to recover the damaged neurons. So I've decided to do two more rolls this year: on Christmas eve and new year. After that I'll give the gray lump a few months to recuperate. Once everything feels sort of back to normal I'll have a celebration pill/bump/stamp/whatever and keep myself to the once a month rule.

Are you sure that the brain can repair neurons?
 
I have been using once a month for two years. I haven't experienced any long term side effects. I don't follow any pre-load or post -load regimen. I usually roll at home with friends never taking more than 2 pills a session. Maybe once every three months I'll go to a club and dance all night. Every experience has been wonderful.
 
I use once a month. I think the side effects when using in that manner are there, but very subtle. When I take a longer break (something like 3 months), I definatly feel the change, a little more stable, more happy in day to day life and generally more content with my life. I think using once a month is fine, but if you're feelin a little "funky" I think an extended brake is in order.
 
I'm definitely starting to realize that my cognitive capacity is changing, and I'm on a very similar schedule to you, started about a year ago. I've noticed that I am much more spacey than I used to be, sometimes struggling to remember stuff that should be on the forefront of my memory.

I've always had an impeccable memory and have been a great communicator, the differences are quite subtle but they're there.

Also, I notice that as the weeks go on from my last MDMA use, things seem to approach "normality" more and more

The differences I've noted are:
-shortened attention span
-Difficulty multi tasking
-differences in vocabulary
-shorter temper
-minor irritability (decreases over time)
-lesser desire to do unwanted things
-a general "foggy" feeling
-more

It is also notable that around march I started taking lorazepam as needed (daily for a few months until I found substantial research on why this is a bad idea)

I'm also living with a partner (gf) for the first time in my life and starting a biz, so there are a number of contributing factors, but I do know MDMA (as much as I don't want to admit) has been a contributing factor.

Is it worth it? Yes, I've had some incredible nights! If this was long term and irreparable id have a harder time making that statement.

I'm also not fully able to say ill be 100% again, I hope that I will. Also, the effects are so minute (writing them sounds way worse that it actually is) that it's not a huge deal to me.

I'm still able to function quite well, I'm still a fun loving person, and still more than capable of dominating the world lol
 
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