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  • BDD Moderators: Keif’ Richards

Can you deplete the Gaba in your brain?

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Droppersneck

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all posts made by the Bluelight username "Droppers
I have abused alcohol and Gaba drugs and ambien drugs for a while. Right now I am constantly dizzy after dosing klonopin/xanax and ambien/beer last night. But I also recently came off my anti deppresent and it may have been too quick. I did celexa for 3 months and steppeddown over a week and half. Anyone with any incite it would be gravely appreciated!
 
You can't really deplete GABA per se... Glutamate is the precursor and is very very common in a lot of the foods we eat. You always are making GABA.

But, you are desensitizing those receptors... Causing them to not be activated as well as while you are fucked up.

This can mean you will become quite epileptic at worse, but very anxiety ridden and not being able to sleep is most common.
 
I think repeated use of certain drugs that effect the gaba receptors such as alcohol, benzos and barbiturates can cause a sort of desensitization to the effects of gaba . I could be completely wrong on that so don't quote me.

I know that after i quit drinking years ago my anxiety got really bad to the point where i had to go on benzodiazepines. I wasn't functional due to anxiety even though i had been alcohol free for a few years. I still take clonazepam but it's no different to me now then say taking my lamictal or bupropion for bipolar disorder. If i forget to take it i will usually have a panic attack around the 30 some odd hour mark but i can get by with less now then when my anxiety was high. But then again the gaba receptor is not the only one by any means that's involved in anxiety.
 
Hi Droppersneck, are you okay? Is hard to tell from your post, but from the thread in general it sounds like you are having a hard time at the moment, especially coming off your meds, and this post does worry me a bit..

I could have got the wrong idea entirely, but if you are having suicidal thoughts, please get some help - ring a friend, family member or even an ambulance.. stay safe <3 suicide is a permanent answer to a temporary problem.. I'll pm you rather than go on too much here!

There is a thread in The Dark Side for people who are feeling suicidal - link is here and general link to TDS is here. It's a great place if you are having a hard time and need a place to vent, or if you want some non-judgemental advice and support <3

If I've got the wrong idea then I apologise, disregard this post ;) but better safe than sorry, I felt..
 
Yeah I saw that too effie..

Droppersneck it does sound like you came off your celexa too fast. It might even
be an idea to go back on it .. get stable then think about dropping the mgs down slowly so your brain can adapt as quickly as possible.
I think if you sense the problem is the ssris you are probably right.. Its your body and you know what its saying to you.

Re the Gaba.. Have you been on any prescribed Gaba drugs.. Like lyrica. Gabapentin etc?

Talk to your doc about your concerns.. I'm sure with a sensible med taper youll start to feel brighter soon enough..

All this pain will pass sweetheart thats for certain. Your brain is really clever at healing it self.

Hang in there! <3
 
Rapid withdrawal from any GABA drugs (Ambien, alcohol, benzodiazepines, barbs, etc) is dangerous.

Droppersneck, if you've been using for a while, I wouldn't take this lightly.
 
^ sorry to hear things aren't going so well.. do take a look at TDS if you want some help or just to speak to others in the same boat - there are a few current threads about people coming off SSRIs and having difficulties, it might help you to read their experiences and share yours :)

Link to TDS is in my earlier post or in my sig.

Take care of yourself <3
 
Droppersneck said:
I think it was the SSRI withdrawl mixed with weed coke ambien and xanax. It was hell.
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No doubt, a cocktail like that and I'd be feeling light headed, dizzy, fucked up, name em all, geesh! I mean I am glad your ok and feeling better, but seriously a ,ix like that alone could have caused that needless to say it could have killed you too. Please becareful, your stepping it close to that 6 foot depth taking a combo like that. That scares me more then they way you put that post, (sorry Effie, Not trying to make lite of the post nor your concern) just making sure that we don't lose focus of the more converning aspect of the feeling vs the cocktail of elixirs there. Be safe, first and foremost.
 
^ It was more the combination of downers really.. no inherent danger in stim + downer, except the risk of one masking the effects of the other, leading to OD. In this case it sounds like it was the cocktail of drugs in combination with SSWI WDs..
 
Is benzo combination more dangerous?

I know most benzos alone the LD50 is so high that you would have to be really, really trying to OD.
 
Benzo combination with what?

You're right, benzos alone are pretty safe in OD, but when combined with other downers they can be dangerous/fatal.
 
Benzos and alcohol can be dangerous, especially if you walk into traffic without realizing it. Add some narcotics and you have the perfect recipe to stop breathing.
 
Sorry I meant combining benzos.

Yeah I have had a very dangerous blackout from clonaz, alcohol and methadone.


And actually stopped breathing on phenobarbital and clonazepam once but that was a genuine attempt to stop breathing. Luckily I had paramedics there to do my breathing for me.
 
Effie not to mention that when you mix stims, and downers, it can play games with your heart rate and that alone can cause major issues, ie heart attack. May seem extreme but its really not especially for someone who chronically abuses alcohol as doing so messes with your electrolytes and many people over look that. Add to that two different drugs acting on the heart in opposite ways, it can be dangerous. I can tell you this as a recovering alcoholic because I have had many instances during and now still while I have been sober, where my electrolytes get so out of whack that my heart begins to should irregular rhythms ect. Again its somewhat extreme, but as this is a harm reduction site,, it can not be over looked, since I deal with this EVERYtime Im in the hospital, I am always put on monitors and watched closely for just this reason. You really have to becareful when mixing this shit. It will kill you.
 
painenduser said:
Effie not to mention that when you mix stims, and downers, it can play games with your heart rate and that alone can cause major issues, ie heart attack. May seem extreme but its really not especially for someone who chronically abuses alcohol as doing so messes with your electrolytes and many people over look that. Add to that two different drugs acting on the heart in opposite ways, it can be dangerous.
Click to expand...

This part is very misinformed on your part.

Mixing uppers and downers is dangerous in certain circumstances, but this one you mentioned about the heart rate is very untrue.

You brain is not playing guessing games. The underlying conditions is what the real culprit is.

If you already know you have irregular ryhtyms in your heart, then drugs sometimes bring them out.

But, if you are a healthy individual, and you are not overdosing, there is no proof of any "game playing" of your heart rate. There is no swinging in your heart rate.

It is well known that anyone with circulatory diseases should not do most if any recreational drugs...

Also, not to mention, if you are in withdrawal from any downer, you should not do any type of upper, not even caffeine.
 
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