Weed-Everyday...Driving stoned can be amazing or it can be uneventful, just depends. I miss my old morning commutes down the coast, smoking all the way.
Benzos- Done it quite a few times and now it isn't too much of a problem if I only took a small dose, but I've popped quite a few tires on benzos so it's definitely not safe. It's mostly just auto-pilot and up to fate/RNG/luck if you make it.
Shrooms- Now this was fun. On the tail end of my second trip I drove a short distance (about 15 min) at night and I remember being on the highway feeling like I was in a spaceship, like the road was just unfolding before me. The tail lights of the cars around me left streams that made me feel like I was flying with them. If you have ever played the game Destiny the best way I can describe the feeling is the intro to a match where you fly in your ship with your teammates.
Alcohol- been there, done that, it's pretty reckless, but obviously a few drinks won't ruin you.
Amps- It's been awhile since I have used adderall/vyvanse, but I do remember driving quite often on it and would describe it as kind of unpleasant, but like any task you can just get stuck doing it. I would often find my 45 min drive to have either felt much shorter, or much longer, and often did not really remember/pay attention to the drive as I was in my head thinking and zoning out. The times that were unpleasant were when I had nothing to do for the day, what should have been a free day that most people would savor, I would waste just feeling like nothing was worth doing and on my drives back I would ruminate and become even more depressed. I would say it basically is mood-dependent.