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RCs Wellbutrin (Bupropion) and RC's, bad combo's, safe combo's.

PowerFarts

PowerFarts

Bluelighter
Joined
Aug 12, 2012
Messages
209
Are you using Wellbutrin as part of a DAILY PRESCRIBED MEDICINE and have anything to share of your experience using research chemicals with it?
Not much on the net surprisingly, so I am coming to you, the user, what have you got to say?
Please mention dosage of the Wellbutrin and the RC's.
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I am taking 300mg's of Wellbutrin daily for ADD since spring of 2013.

I have not consumed my 25i-nbome since, would like to try 750mg's as a test sometime.

Just got some aMT, may just put that on the backburner for awhile? (maoi)


Since starting wellbutrin:
-I have consumed up to 15mg's of 5-meo-mipt.
-Consumed by arse packing (plugging), up to 200mg's of ethylphenidate, 50mg's at a time over 4-5 hours.
-Methiopropamine, up to 60-70mg's oral and plugged.
-Consumed beer despite warnings.
-Acetildenafil (Hongdenafil) up to 15mg's in a single dose.
-Weed (of course)

Will be trying MXE soon!

So, sit down, roll up your sleeves, clear your throat, get up, run to the toilet and spit, come back, sit down, and tell me how you made out.
I need to know this stuff, or any other pertinent information you may have to share.

Thanks.
 
slightly off topic but I was just incarcerated for 30 months and the "thing to do" was to hide your WB's(they call em wellies)and sell them for $2 of canteen or to sniff them. They claimed it was similar to coke. I had never heard of this. Is it true or were they just acting out of desperation? sorry for getting off the track......
 
If you're taking Wellbutrin, expect diminished effects/negative interactions from stimulant usage.
 
I just recently read an article about people Injecting wellbutrin.
Not good, huge abcesses. Memories of krokodil.

Anyway, they find it addictive.

So, to stay on topic, anyone else have RC / wellbutrin experiences?
 
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sekio said:
If you're taking Wellbutrin, expect diminished effects/negative interactions from stimulant usage.
Click to expand...

Seems fine with ethylphenidate, and it it sometimes prescribed with stims. However, I have never had eph sans wellbutrin, so I cannot compare.
 
Be cautious mixing things with bupropion. Its already a dirty enough beta-ketone amphetamine by itself.

I would definitely not mix it with aMT or amphetamines. I am trying to remember if I mixed it with anything when I was taking it. I'm pretty sure that I drank on it but that's about it. Be careful, it potentiates a number of drugs and its also a nAChR antagonist. I don't have the exact list off hand but to be safe, if you're going to mix it with anything, I would try a dose that was a quarter of what would usually be a moderate dose and titrate up.
 
nAChR?
Going to have to look that one up.

Titrate up, yes.
Current research with 300mg wellbutrin xl at about 4:30am, at about 6:30pm, 10mg Methoxetamine allergy test is done.
Cannabinoids were added.
Now it is 8:08, 0.5 can beer added to research.
Something more than THC is at work here, that has been detected.
Faint.
 
I don't know about XL but the regular instant release Wellbutrin gave me a crappy generic cathinone stimulant feeling that was both long-lasting and uncomfortable.

I've thought about it and now I remember - alcohol was significantly stronger with Wellbutrin. You also had to watch your intake because they both lower the seizure threshold. I didn't mix it with any hallucinogens or other stimulants that I can think of but that doesn't mean I didn't do it. I don't remember a lot of the stuff that I did back then and its very well possible that I was abusing mephedrone and/or methylone around that time now that I think about it. Its really hard to say. I was crazy reckless back around that time, regularly mixing things that shouldn't be mixed.

There is one property about that drug that I loved. Just like mephedrone, it turned me into a total hornball. LOL

nAChR is the nicotinic acetylcholine receptor. Here ya go -> http://www.scholarpedia.org/article/Nicotinic_acetylcholine_receptors
 
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i take 300mg of bupropion a day too. tried some mdma with it one time, really uncomfortable, sweaty, shaky. synthetic noids were also a mistake. however, i notice that it since i started taking it 9 months ago that I've been smoking a lot more weed. (combines well with WB)
 
nAChR- Yes, yes, the nicotine thing just as I suspected but was unsure of, and obviously the XL is a lot smoother and as a consequence the seizure threshhold is much higher, comparable or better than the SSRI's, I think the XL is a lot less risky. Somewhere I read that it was necessary to create an extended release for that reason.

ikeibeabuchi, I read that MDMA was bad news, good news is, I have never found real MDMA (was too late in the game) so extasy is low on my list of enquiry.


Was feeling a bit DXMmy last night, at least very threshhold desocialism was felt, walking coordination was effected, hints of speech impediment. Almost like DXM in that a small dose can tell you how a larger dose may feel.
Either:
-cheap milligram scale underweighed the sample
-high quality shit
-sensitised by the wellbutrin.
-some other perameter

Read that MXE got along OK with wellbutrin, so I will titrate up, but it will be a bit as a job is imposing on my research time, yet I need the job to fund my research (and my life in general).

PS, coffee goes great with bupropion, caffiene synergises really well with it.

So...Bupropion heads, keep sharing info, it's important that you do, the internet is lacking in info.
Sometimes though as I have found, if on the net you find nothing on a subject, it is usually not a concern.

And the aMT I have, it's an MOAI, the warning is not to consume MOAI's until 2 weeks after stopping bupropion.
(Not even a taste? A bit of a pipe sample?)

Certainly there must be a safe level for a moderate amount?
 
aMT is a weak MAOI but it has a sketchy pharmacological profile. Its a triple releaser so its likely to have some sort of unpleasant interaction with bupropion. Its a tryptamine but its very much a stimulant. I would hazard a guess that people who blind tested it who had experience with both phens and tryptamines would liken it to a phenethylamine more than a tryptamine. I'd be worried about pulse and blood pressure from the interaction of the two but I don't know anyone who has mixed them. It doesn't tend to like being mixed with anything. If you do try it, be extremely cautious.

For what its worth, the only info I can find on the combo is a TR on Erowid where a guy took 140mg who was on Wellbutrin and had a seizure. But 140mg is insanely high by itself. I pushed my dose to well over 100mg administered in various ROAs over around 7-8 hours and when the last dose hit me I was so fucked that I couldn't talk for a good hour because my jaw was bouncing around so much that my words came out in stutters like something you'd hear them do to someone's voice in a psytrance song. My friend almost took me to the hospital but I pulled out right as she was coming up on the hospital intersection and we went off to the mountains and did our music thing as we planned. I'm not surprised that 140mg would give someone a seizure with or without meds as my incident didn't involve any other meds...

https://www.erowid.org/experiences/exp.php?ID=21703

As always, titrate. Its really hard to do with aMT though because it can take 3 hours to plateau and the urge to redose is pretty strong with it if you're not where you want to be.

And most certainly do it orally, don't smoke it. Smoking it adds to the intensity, keeps roughly the same come up and duration, and increases the bodyload. Smoked, it reminds me more of a very scattered and confusing psychedelic speed than the blissful mildly stimulating yet sedating (kind of like a nice hefty dose of clean MDMA actually) and sweetly psychedelic drug that I know and love when I eat it orally. Snorting it burns like what I would imagine it would be like to snort glass shards and resulted in me screaming as my membranes pulsed in agony and then profusely flushing my nose for the next 10 minutes with a burn that lingered for another hour.
 
Wellbutrin has zero abuse potential and will give you a seizure if you overdose.
 
Kat, I had replied to your last post, but my reply went AWOL for some reason?
In my reply I was not happy that most of the bad combo info was a result of recklessness, not regular normal people doses, like your erowid link that I also read. The guy was negatively affected, but lived through it, how would he have made out with a more moderate responsible dose?
 
PowerFarts said:
Kat, I had replied to your last post, but my reply went AWOL for some reason?
In my reply I was not happy that most of the bad combo info was a result of recklessness, not regular normal people doses, like your erowid link that I also read. The guy was negatively affected, but lived through it, how would he have made out with a more moderate responsible dose?
Click to expand...

It seems to be a common theme with beta-ketone amphetamines in general that people do stupid crap while on them. It wouldn't surprise me if this applied to bupropion as well. I remember being rather impulsive when I was on it and not really caring too much about things. It really did remind me of a mildly dysphoric long-lasting cathinone feeling. It wasn't pleasurable or even remotely recreational but it definitely had some traits that I only really get with the cathinones, especially the literally insatiable sex drive and the impulsive push to do things without thinking about the consequences. I'd say it made me manic but mania is an entirely different experience for me. Oddly enough, bupropion was the only antidepressant besides mirtazapine and trazodone that didn't induce mania in me.

In any case, I can't say much for aMT in combination with an antidepressant. At the time that I was using it, it WAS my antidepressant - and an extremely effective one at that. I am with you in that I wish there was more evidence but if you think about it, bupropion isn't very commonly prescribed as an antidepressant in the first place. The SSRIs are the first line, then the SNRIs, bupropion tends to be last on most doctor's lists. It wasn't even on my doctor's list at all until we exhausted everything including Lyrica for my anxiety disorders and I suggested a trial of it.

In the interest of harm reduction, I'd have to say that careful titration is necessary. aMT on its own can be a rather intense experience and its long-lasting and not able to be aborted with benzodiazepines so once you take it, you're in it for the duration. Even if it doesn't end up being inherently dangerous, the wrong combo can at least make for 16+ hours of a living hell.
 
I read on wikipedia the other day that Wellbutrin has no abuse potential. At first I didn't believe that, so I kept titrating up my doses until I had a seizure in public.

Yes. I believe it to be true that Wellbutrin has ZERO recreational potential after that.
 
I requested wellbutrin myself, the Strattera she (nurse practitioner) originally prescribed gave me unacceptable sexual side effects.
The wellbutrin gives me no major side effects (lately though I find myself clenching my teeth)

Isn't aMT's trip duration dose dependent? That's what I have gathered in my info seeking. So, if that is the case, I could aim first for an anti-depressent level buzz, then sub-psychedelic without a major time commitment?
 
Who told you that aMT is dose dependent? Its duration is no less than 12 hours from start to finish no matter what dose you take. Its a serious time commitment even with a threshold 10mg dose. I've had doses ranging from 5mg on up to around 90mg or so and its pretty consistent that aMT has a 10-14 hour trip which has something like 4-5 hours where it hits a peak in the plateau but the rest of it is a level plateau and then you have to tack on time for the come up (took an average of 1H45M for me to hit the plateau I'd say with 30 minutes being my quickest (that was with my highest oral dose I ever did and I think my empty stomach plus the Sprite I was drinking had something to do with that) and just over 3 hours being my longest) and the coming down period is another good 4 hours or so. Total experience averages 14-18 hours start to finish with sleep not really possible until T+22 or later.

With mescaline an aMT both, I make sure I have 24 hours set aside plus at least 8 additional to recover (sleep really, there's no crash, its pure afterglow)
 
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I will take your word on the trip duration.

An idea I am formulating is to wean off the wellbutrin using 3,4 CTMP (RC long duration ritalin) just long enough try a thing or two.
But just how long to clear bupropion from my system?
And no bupropion 2 weeks after a MOAI (, must I really wait that long?

I really don't want to mess with my medication, but...
 
If your meds are working for you, I really wouldn't recommend coming off of them to get high. For one, antidepressants are absolutely notorious for not working when you take a break and go back on them later and two, you don't want to go unstable.

I wouldn't use an RC to taper off of a med under any circumstances.

aMT is not a strong MAOI and its also reversible so the 2 weeks doesn't apply here. In testing, aMT was found to be roughly as potent as harmaline as an MAOI which is to say that its not potent at all. Harmaline takes around 150mg to make DMT orally active. aMT doses are really between 20 and 40mg for most people with anything above that being considered a high dose (of course bear in mind the 20% potency increase that freebase has over HCl) so its highly unlikely that it has significant MAO inhibition in recreational use.
 
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