Hello all,
I have been reading/checking in on this thread off and on for what must be a couple years, and since activating my account have decided to drop my two cents. I know this thread is old, but after reading through the entire thing (which, as you may have noticed, contains some redundant suggestions regarding insufflation methods), I decided that I had a bit of perspective that people may find useful when considering a MoA.
I wouldn't bestow any method I'm listing here my stamp of approval, so don't get the wrong idea, but i can share with you what I've experienced/observed with some of the different M's'o'A. THERE IS NO SAFE WAY TO INJECT THESE PILLS, please do not mistake accounts of experience for suggestions. If anything, please pay close attention to the negative side effects I have experienced from experimenting with these methods.
(Let me first clarify that, unless I specify otherwise, I am talking about the new, round, concave, Opana ERs with an "E" on one side and a number on the other. I have tried an assortment of these (including the 40mg, 30mg, and 15mg) with lightly varied results - mostly due to the size/chemical makeup or proportions)
The first method I attempted, mainly because I didn't have any prep gear, was chewing, which was an improvement over swallowing whole, but the effect of an entire 40mg pill merely became mildly noticeable whereas I couldn't tell I'd even taken anything when I swallowed one whole.
When I felt it was safe to re-dose, I decided to grind one of the 40s and snort it (trying both the Dremel method and the microplane method (the dremel method is far superior, btw)), but the polymers in the pill make it dissolve inconsistently and it seems that the 'powder' fails to absorb effectively. I will say that this method seems to produce a very noticeable jump in bioavailability compared to oral administration, but the powder is not ideal for snorting.
I later attempted an isopropyl alcohol extraction for injection, which was a wicked pain in the ass, but produced enough of a boost in bioavailability and extraction efficiency to motivate me to keep experimenting.
Here's what I did (THIS DOES NOT PRODUCE A CLEAN EXTRACTION AND IS SHOULD NOT BE MISTAKEN FOR A SAFE METHOD):
1. Using an exacto blade, I carefully shaved off the colored coating (which keeps things a little cleaner, but may not be necessary).
2. I took the microplane to the pill using needlenose pliers to grip the pill. After 20 minutes, I was left with a pile of powder and some strings of rubber that rolled up as I was grinding. I chopped these into tiny bits and placed them in a 2oz metal ramekin, adding roughly 1.5 oz of 94% isopropyl rubbing alcohol. I stirred the solution every thirty seconds to one minute with a toothpick. After 10-15 minutes, the 'blob' we keep hearing about formed in the bottom of the glass, but with light agitation, the blob would separate into a suspension. I continued to do this for around 45 minutes.
3. After my final stir, I let the 'blob' reform in the bottom of the ramekin and, using a needleless syringe, lifted the liquid from the upper portion of the mixture, leaving a little as possible in the container, but being careful not to suck up any goop. (the liquid will all be a little bit viscous, especially toward the bottom of the container, but there is a distinct difference in the liquid portion and the 'blob').
4. Using a 3cc needleless with some cotton packed into the end, I filtered the liquid portion into another 2oz metal ramekin (a 2oz ladle can be used instead) and placed the container on the stove eye (you need a coil stove for this to work, as open flames will cause the isopropyl alcohol to combust). Slowly adjusting the heat from low on up, I found the setting that allowed the solution to evaporate without boiling (tiny bubbles will begin to appear on the bottom of the ramekin, but will not rush to the surface). Once the visible liquid was evaporated, I scraped the light golden powder from the bottom and allowed it to sit out until it was completely dry and no longer smelled, even faintly, of alcohol.
5. This resultant powder is soluble in warm or cold water, and is injectable.
The problem with this method is that, while it produces a powder that can be injected, the OM does not appear to efficiently leech into the liquid. Subsequent rinses and the repeat of steps 2-5 may remedy this, but holy fuck, what a pain in the ass!... not to mention the anxiety produced by resorting to injecting all of those fillers. All else aside, I personally suffered no adverse affects from doing this (but I suggest reading the thread containing the FDA warning regarding the injection of these pills to further educate yourself about the dangers involved)
I actually evaporated the remaining isopropyl alcohol out of the blob using the stove as described above and swallowed the resultant taffy-like wad. This produced a noticeable boost in effect with the 40mg variety.
Because this was not working as well, and I was bound and determined to successfully inject one of these pills, I started going over my notes on 'crisping' and began to experiment. At this point, I had access to the 30mg variety (yes, the concave pills again), but have tried this with the 40s as well with similar results.
Here is what I did (THIS IS NOT SAFE):
1. I used an x-acto blade to remove the colored coating, cut one 30 or 40mg pills in half, and placed it in my spoon.
2. I then began to heat the spoon from below with a butane cigarette lighter, applying maximum heat until the pill puffed up (i.e. was no longer concave and had started to puff out upwards).
3. After softening the half-pill, I took the butt of a bic lighter (ideally lightly moistened) or another blunt, smooth object and flattened the half-pill until it was roughly the size of a dime, flipping it in the spoon when it started to curl until it eventually stuck and began to melt. This portion of the heating calls for/requires MUCH less heat than you used in step 2, as you do not want to burn the pill or evaporate even larger portions of the OM. If heated slowly and while moving the flame around, a light brown/honey coloration can be achieved.
4. Once 0% of the pill was white any longer, I would set the spoon down on an insulated surface and let it cool just slightly.
5. At this point, I would add 2cc - 3cc of water and agitate the pill with the flat end of the plunger, only scraping the spoon in one direction to help it dissolve into the water as slowly as possible so there aren't any floaty bits that should be dissolved.
6. I would then use a needleless 1cc syringe and pull 80-90 units through cotton or other filter if it's handy (double filter, especially if any floaters are present (if the coating was cleaned off at the beginning, the presence of visible floaters in the solution can be minimized), and pull the solution up into a brand new, sharp 1cc syringe. If done well, the liquid will be mildly viscous - roughly the consistency of a very light syrup (maybe comparable to the liquid from fruit cups with fruit juice... just slightly more viscous than water). I would then inject the solution and repeat every so often until satisfied.
This method seems to deliver the OM effectively and quickly. I would speculate that the efficiency of extraction and delivery feels like it must be over 50%. Unfortunately, problems can arise right off. I noticed that even a partial miss/jump (even a drop) would cause irritation of the veins and surrounding tissue. This would typically only leave you with a knot or hard spot in that area and a swollen vein that needs time to heal. In some cases, abscesses can more easily result (likely due to the body's inability to rush the substance away from the affected area, and the subsequent festering of bacteria that may be present in the shot/liquid). Once again, you'll need to look at the thread I mentioned followng the previous extraction method for more info on the dangers of injecting these pills. I witnessed other immediate adverse effects resulting from the use of this method, and I have watched about a half dozen other people try it multiple times. I used this method myself to inject 4-12 pills per month (I was given some extra pills from a friend's prescription once a month) over a period of about 6 months and feel like I escaped any real short-term damage (as far as any long term damage that plans to rear its head down the road, I cannot say). I have noticed that the occurence of cotton fever seems higher when using this method, and I did suffer a surface abscess (which, because it was so close to the surface of my skin, resulted in relatively mild discomfort until I drained it) which I suspect may have been related to injecting concave opana ER pills, but I am not 100% sure.
As for the immediate adverse effects mentioned above (and this happened a couple of days ago): A friend of mine prepared and injected some opana ER solution after crisping and immediately turned beet red from hypertension and was having trouble breathing. This was his first time using this method and his solution was darker than mine usually is. He was also in a hurry and may not have filtered as well as I typically do. In 5 minutes, homeostasis seemed to return, and in 30, his breathing/blood pressure returned, basically, to normal. After another 4 hours had passed, he still felt pretty badly beat-down, but was no longer in a state of terror. I'd like to state that I put my shoes on as soon as I noticed his symptoms and prepared to rush him to the hospital. This did not wind up being necessary, but, man was it a scare. His health and/or life seemed at great risk. He re-dosed opiates much later in the evening, and reported to feel much better. When he woke up the next day he could barely move. All of his joints were so inflamed he couldn't bend them. Even his fingers were locked up. He did not re-dose, so his feeling better the night it happened may have resulted from the masking effect of the opiates he took. We have heard rumors of the major local walk-in clinic working with the authorities to crack down on IV drug abuse, so he is afraid to go in (I'm pretty sure that can't be legal at all, but somehow it wouldn't surprise me). Has anybody ever heard of anything like this happening? I think he is done using opana ER via IV, but I really wish I could figure out some way to help him in the mean time (and please don't tell me he deserves whatever he gets, that would be counterproductive).
I managed to muster the will power to refuse to inject any of the solution, but another friend finished the solution and did not have the same experience, so I am left to suspect that poor filtering was, at least, partially responsible.
Any time I used the crisping method for extraction, I did so due to a fear of withdrawals in the midst of a shortage in cash which leads to mild complacency. At best, this method works (to the extent that you can successfully (not safely) deliver the OM), but is in no way ideal. I fear that the long term effects will certainly outweigh the short term risks discussed above, so please be very careful and try not to resort - people do very dangerous things when they are desperate (as is apparent in this post). INJECTING THESE PILLS IS NOT SAFE. EVER.
Does anybody else have experience with with some of the methods above that were not discussed prior to this post? I am curious what is behind some of the side effects that I could not really wrap my mind around.