Mushroom Substrate Potentiation
Welcome to the main thread for tryptamine doping of mushroom substrates
research doc: Biotransformation of tryptamine derivatives in mycelial cultures of Psilocybe
Relevant Shroomery Threads: 1 2 3 4 5 (5 has an awful lot of amazing links)
Trip Report of DiPT-doped mushrooms
[original post:]
Let's say I were to put DiPT in with spores of mushrooms. Would the products be both Psiloc(yb)in and Iproc(yb)in?(Would that be iprocybin or something else, anyway?) Or just Iproc(yb)in?
Just wondering. Also, would the potency be effected if DMT were added in the same way?
Welcome to the main thread for tryptamine doping of mushroom substrates
research doc: Biotransformation of tryptamine derivatives in mycelial cultures of Psilocybe
Relevant Shroomery Threads: 1 2 3 4 5 (5 has an awful lot of amazing links)
Trip Report of DiPT-doped mushrooms
(http://www.erowid.org/library/books_online/tihkal/tihkal16.shtml)"Some fascinating studies have been done in Germany where the metabolically active mycelium of some Psilocybe species have been administered diethyltryptamine as a potential diet component. Normally, this mushroom species dutifully converts N,N-dimethyltryptamine (DMT) to psilocin, by introducing a 4-hydroxyl group into the molecule by something that is probably called an indole 4-hydroxylase by the biochemists. You put DMT in, and you get 4-hydroxy-DMT out, and this is psilocin. Maybe if you put Mickey Mouse in, you would get 4-hydroxy-Mickey Mouse out. It is as if the mushroom psyche didn't really care what it was working with, it was simply compelled to do its sacred duty to 4-hydroxylate any tryptamine it came across. It was observed that if you put N,N-diethyltryptamine (DET, not a material found in nature) into the growing process, the dutiful and ignorant enzymes would hydroxylate it to 4-hydroxy-N,N-diethyltryptamine (4-HO-DET) a potent drug also not known in nature. This is the title drug of this commentary. What a beautiful burr to thrust into the natural versus synthetic controversy. If a plant (a mushroom mycelium in this case) is given a man-made chemical, and this plant converts it, using its natural capabilities, into a product that had never before been known in nature, is that product natural? What is natural? This is the stuff of many long and pointless essays."
[original post:]
Let's say I were to put DiPT in with spores of mushrooms. Would the products be both Psiloc(yb)in and Iproc(yb)in?(Would that be iprocybin or something else, anyway?) Or just Iproc(yb)in?
Just wondering. Also, would the potency be effected if DMT were added in the same way?
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