LordKrishna
Ex-Bluelighter
- Joined
- Aug 29, 2008
- Messages
- 444
Im an addict, and the thought of only getting 40-50% of the drug to brain is even more scary then any other MOA.
IV and I stand by it!
IV and I stand by it!
That's why you plug it, ~90% bioavailability. I prefer plugging opiates versus IVing.LordKrishna said:Im an addict, and the thought of only getting 40-50% of the drug to brain is even more scary then any other MOA.
IV and I stand by it!
no it doesn't, and to the person who suggested snorting MS cotton that has EVEN LESS.sunset117 said:why not just take them orally, it has a high oral bioavailability and is obviously relatively safe
LordKrishna said:no it doesn't, and to the person who suggested snorting MS cotton that has EVEN LESS.
with morphine IV is a almost must in order to get high without taking an insane amount. I can promise that the people who eat 100mg would be GONE from shooting as low as 35.
Iv noticed that even as low as 15mg I can get a descent rush. the rush doesn't last, but I feel it none the less.
Iv ate, snorted and plugged MS cotton and by far IVing it has been the greatest MOA.
morphonorconic said:I enjoy insufflating my MSContins just fine.
** Yes. First, I sniff a small amount of chitosan powder into each nostril and let it sit and do its thing for several minutes.* Then, I add about one part chitosan for every 20 parts morphine sulphate and mix it homogeneusly before insufflation. And I find that it is extremely important with time-realease morphine sulfate that it be crushed into as fine a powder as possible to avoid unnessecary delay of the delivery into your system. They say that chitosan is very bioadhesive and increases the spreading and adhering of the powder mix over the nasal membranes. It is also said that it is able to increase overall amount absorbed by the membranes by opening up otherwise inactive receptacles in which the morphine can be absorbed. So in a sense, seemingly, chitosan opens the barrier that is responsible for morphine's poor nasal absorbtion.ATF said:Are you talking about 'cutting' the morphine w/ chitosan and snorting it? Or ingesting chitosan and then snorting? I wonder how it increases the bioavailability? Nasal abrasion?And is MS-Contin snortable as is or does it need extra super fine crushing or something? I know that the finer the better, but is it formulated to make this difficult?