i have posted this information before via reply to a previous thread, but it did not seem to be widely acknowledged or accepted....well, now i have found yet ANOTHER reliable site confirming what i had said; oxycodone HCL is absorbed less effectively when snorted.
for those of you who arent familiar with me, i used to abuse oxycodone on a regular basis(daily lol) for a couple of years...before i went onto methadone, i was using over 400mg of crushed oxy or oxy-IR at once to get high. before my tolerance got to that point, i did sometimes ingest my oxy by snorting some or all of it. however, when it got over the 200mg mark, i started noticing that it was seemingly not as strong when i snorted my dose verses taking it completely crushed orally. i thought it was in my head or the fact that the high amount of oxy i was needing required many more pills and therefore had alot more fillers/binders that were probally not water soluble and were clogging up my nose preventing full absorbtion of the oxy when snorted...maybe a combination of both lol.
then i finally came across a reputable source a while back that claimed oxycodone HCL was indeed absorbed more efficiently when taken ORALLY by a decent margin when compared to insufflation/snorting. i never got specific numbers but i just happened to stumble across the article on wikipedia about oxycodone and found some good figures that might be of interest to those who use oxy; especially insufflated. basically a good 20% minimum increase....
snorted=46-47% availability vs. oral=60-87% availability
see for yourself:
i admit i am fairly suprised that it is that large of a difference. i always suspected oral was better but for the reasons stated above, i never could say for sure. now im glad i not only saved my nose the hassle/pain of snorting all that oxy, but also helped my wallet stay a little fatter by getting the most outta every pill.
so i hope some of you will take this information to heart and stop snorting your oxy if possible...i know some people just simply prefer the slightly quicker onset and feeling, but with a significant efficiency advantage taken orally, it may convince some of you to just crush and swallow your OCs/oxy/percs/roxis/whatever from now on.
hope this helps,