I've withdrawaled many times with many different aids. In-patient and doctor facilitated withdrawal at home was made EASY with:
Phenobarbital
Clonidine
Loperamide
Ropinirole
In the past, i've usually used a strong benzo (2mg alprazolam) in place of the pheno, as I only know one doctor that will give it to you for at-home withdrawal (he's an old Dead Head, not surprising).
Without the pheno or a benzo, I'm doomed to fail before I enter the hell of PAWS.
I'm opiate-free almost 2 months now (longest time in 5 years) from 500+ oxycodone a day, plus typically 32mg hydromorphone as well. I'm somehow still sober and, even more surprising, no longer forging prescriptions (thank god the doctor whose name I forged just wanted to see me get off opiods and didn't press charges).
Did the in-patient detox in the beginning of October 2015. I'd recommend it to anyone who can access it w/ isurance or has the money to pay
If I had to choose from stuff that's easy to get from a doctor or is OTC:
Clonidine (BP med; very important!)
Loperamide (for the GI nightmare)
Ropinirole (stops violent leg kicking)
Quetiapine (sleep)
Trazadone (sleep)
Methocarbamol (muscle aches/spasm) Gabapentin (anxiety)
Lyrica (anxiety, sleep, mood)
Carbamazepine (mood stabilization)
I personally got nothing out of the Trazadone, but some people seem to be scared of Quetiapine due to it being an anti-psychotic; I mean, it's really is an atypical AP, and in doses of 25mg-100mg, I have never experienced weight gain, akathisia, tics, dyskenisia, etc. Though, for the sake of harm-reduction, use discretion and research. Methocarbamol seems to help a little with the muscle aches and paina. Gabapentin never did a thing for me, Lyrica is way better (read: way more pontent).
Hopefully someone got some useful information from my post/short-novel.
EDIT: if Pregabalin (Lyrica) is chosen over Gabapentin (Neurontin), one should be aware that it is a Schedule V drug in the U.S. with abuse and addiction potential, and "liking" for the drug, according to at least one study, may be increased by previous or current opiate/opioid use. I have a research article ("Pregabalin abuse among opiate addicted patients," by Grosshans et al.; European Journal of Clinical Pharmacology, 2013, 69:2021-2025) to share if anyone is interested... I actually have quite a few pregabalin studies in general.
The addictive qualities of PHENOBARBITAL and ALPRAZOLAM speak for themselves (hopefully...)