This is a question that is coming back to me again and again.
So let's understand the basic philosophical meaning of this question. In my opinion the basic information in philosophy and psychology (beside information that "I exist. I'm experiencing. I'm feeling good or bad.) is the Motivational System that is the same for every human being on this planet (and most likely for all animals and arguably for all creatures in the universe) which we can define as:
"I will move in the direction, change in the direction that I believe will feel best (is the most pleasures) for me. And that I will always move away from the direction that I believe will feel worst (that is the most painful) for me.
So this is the ultimate goal of people on this planet. Everything that we do is beucase we want to feel better. Everything else that we do or want to experience or achieve we will experience it better and achieve faster if we feel good. But even if this wouldn't be the case and people would just be partying and sitting on their couch in the euphoria, so what if the goal was already achieved? How suffering is better by wanting to achieve something greater let's say more advanced civilization if this is achieved by mental suffering (or for some even torture) of billions of people? It doesn't make sense because even general advancement in civilization is also to make us happy because of it. But anyone who ever took some cool stimulant knows that they make you more creative and wanting to do things.
Feeling good is all that we want. Everything else that we want to achieve in our civilisation would be better if the mental suffering of people would end. For example by some super effective psychotherapy or some extremely effective drugs (e.g. like combo Adderall + Oxycodone. Or something that works more organically in the direction of Bromantane or supplements but, of course, stronger than that). Or both.
So why all governments, scientists, psychologists, universities, pharmaceutical companies, etc, are not focusing on this most important question in the past and future history of humankind?
Why there's no gigantic strive on the internet, universities, schools etc. for answering this question on how to create a perfect substance (and/or therapy) that would make us come out suffering and live in constant joy, happiness and euphoria, or at least (complete) inner peace?
Why most of scientists of neuroscience and psychology will not commit themself to it, so that people can be free from suffering either through drugs or a very good (and easy) psychotherapy method(s) that can be taught via YouTube video or a one (rather short) book, or both.
Pretty much all people suffer more or less (especially those with screwed up brain chemistry and/or very bad childhood)
The thing is that no matter how suicidal I am - when I take Oxy - I'm always back to extreme happiness, I'm back to optimistic thoughts and feelings, and pretty much nothing can make me feel bad.
So why there's no gigantic amount of work and commitment to invent an opioidergic drug that organism wouldn't develope a tolerance for?
Antidepressants are developed since about 60 years. We live in 2018 and current Anti-depressants are still pretty shitty. If you want to have complete relief, you have to properly involved at least one of those 3 neurotransmitters: Dopamine, Opioderic System (mainly Endorphins) and GABA. (Gagabapentinoids like Pregabalin are an exception to this.). But there are no antidepressants that are doing it. Except of ADHD meds and Bupropion that are one of most wanted drugs in the whole psychiatric pharma business.
I know that brain will build up a tolerance to the euphoria.
But first: this is not something that is happening to current antidepressants (SSRI, SNRI), Adderall works more or less all the time and after some tolerance built up you can reverse the tolerance with e.g. Memantine and after that take things like Agmatin, DXM, Magnesium, Turmeric etc. to hinder the tolerance build up.
Why there's no work developing something like Endorphine Reuptake Inhibitor?
And if tolerance is a problem, couldn't all scientists in the world solve it?
For example by creating a drug that would not affect the part of the brain that is responsible for tolerance development so that this part would not notice the drug, but the path that is creating good feelings would notice it. Or a drug that would prevent the tolerance development.
I know that you will probably say that pharma will not spend money on researching and developing a substance that will eventually make them lose money baucase of drop in sales of bigger doses and dramatically lowering sales of other antidepressants and painkillers (or some other reason that I don't know).
But let's look at that this way:
Some pharmaceutical company developed a drug that would be a perfect antidepressant and at the same time painkiller (affecting dopaminergic and opioidergic systems in the brain) and patented it for 10-15 years and sell a drug that would outsell all other "good feeling" drugs on the market. So the question is why after so many decades of demand by increasing amount of people with anxiety, depression, ADHD, committing suicide, addiction and people that take all sorts of drugs - no company ever mentioned that they are working on something that would be practically
a salvation for humanity?
Edit:
" I don't necessarily mean "complete happiness". I don't even think it's possible because the point is that I also believe happiness is infinite, so we can never have a complete happiness in a sense of not being able to be more happy. The complete happiness I'm reffering to is the complete inner peace. And also that no matter what happens - it can never gets painful (besides basic survivale mechanisms, but the amount pain that people today expierience is not even near the needed to survive - e.g. on Oxy also feel enough physical pain to move away from something that my body is warning me against.). The whole point is there should only be inner peace with excitement as "additional" happiness or as "a carrot". And there should be (almost?) no stick (most of the time?) because it's presence is the interaption to the goal it should "bit you" towards.
The only logical sense of suffering and pain that beneficial is being more able appriciate your happiness when you have it. Which explained by the rubberband analogy: The more you put rubberband into the darkness, when you let it go into to the light (happiness) - the further it will go into that direction. But first we have to let it go sometime. "
"Yes, but having a complete inner peace (which I mean by complete happiness), wanting more would not be a problem. It would be like "I'm fully peaceful, at ease and content, but I want excitement (/more excitement) that's why I'm doing stuff that's excites me (probably mostly in the world as oppose to imagination). "
So let's understand the basic philosophical meaning of this question. In my opinion the basic information in philosophy and psychology (beside information that "I exist. I'm experiencing. I'm feeling good or bad.) is the Motivational System that is the same for every human being on this planet (and most likely for all animals and arguably for all creatures in the universe) which we can define as:
"I will move in the direction, change in the direction that I believe will feel best (is the most pleasures) for me. And that I will always move away from the direction that I believe will feel worst (that is the most painful) for me.
So this is the ultimate goal of people on this planet. Everything that we do is beucase we want to feel better. Everything else that we do or want to experience or achieve we will experience it better and achieve faster if we feel good. But even if this wouldn't be the case and people would just be partying and sitting on their couch in the euphoria, so what if the goal was already achieved? How suffering is better by wanting to achieve something greater let's say more advanced civilization if this is achieved by mental suffering (or for some even torture) of billions of people? It doesn't make sense because even general advancement in civilization is also to make us happy because of it. But anyone who ever took some cool stimulant knows that they make you more creative and wanting to do things.
Feeling good is all that we want. Everything else that we want to achieve in our civilisation would be better if the mental suffering of people would end. For example by some super effective psychotherapy or some extremely effective drugs (e.g. like combo Adderall + Oxycodone. Or something that works more organically in the direction of Bromantane or supplements but, of course, stronger than that). Or both.
So why all governments, scientists, psychologists, universities, pharmaceutical companies, etc, are not focusing on this most important question in the past and future history of humankind?
Why there's no gigantic strive on the internet, universities, schools etc. for answering this question on how to create a perfect substance (and/or therapy) that would make us come out suffering and live in constant joy, happiness and euphoria, or at least (complete) inner peace?
Why most of scientists of neuroscience and psychology will not commit themself to it, so that people can be free from suffering either through drugs or a very good (and easy) psychotherapy method(s) that can be taught via YouTube video or a one (rather short) book, or both.
Pretty much all people suffer more or less (especially those with screwed up brain chemistry and/or very bad childhood)
The thing is that no matter how suicidal I am - when I take Oxy - I'm always back to extreme happiness, I'm back to optimistic thoughts and feelings, and pretty much nothing can make me feel bad.
So why there's no gigantic amount of work and commitment to invent an opioidergic drug that organism wouldn't develope a tolerance for?
Antidepressants are developed since about 60 years. We live in 2018 and current Anti-depressants are still pretty shitty. If you want to have complete relief, you have to properly involved at least one of those 3 neurotransmitters: Dopamine, Opioderic System (mainly Endorphins) and GABA. (Gagabapentinoids like Pregabalin are an exception to this.). But there are no antidepressants that are doing it. Except of ADHD meds and Bupropion that are one of most wanted drugs in the whole psychiatric pharma business.
I know that brain will build up a tolerance to the euphoria.
But first: this is not something that is happening to current antidepressants (SSRI, SNRI), Adderall works more or less all the time and after some tolerance built up you can reverse the tolerance with e.g. Memantine and after that take things like Agmatin, DXM, Magnesium, Turmeric etc. to hinder the tolerance build up.
Why there's no work developing something like Endorphine Reuptake Inhibitor?
And if tolerance is a problem, couldn't all scientists in the world solve it?
For example by creating a drug that would not affect the part of the brain that is responsible for tolerance development so that this part would not notice the drug, but the path that is creating good feelings would notice it. Or a drug that would prevent the tolerance development.
I know that you will probably say that pharma will not spend money on researching and developing a substance that will eventually make them lose money baucase of drop in sales of bigger doses and dramatically lowering sales of other antidepressants and painkillers (or some other reason that I don't know).
But let's look at that this way:
Some pharmaceutical company developed a drug that would be a perfect antidepressant and at the same time painkiller (affecting dopaminergic and opioidergic systems in the brain) and patented it for 10-15 years and sell a drug that would outsell all other "good feeling" drugs on the market. So the question is why after so many decades of demand by increasing amount of people with anxiety, depression, ADHD, committing suicide, addiction and people that take all sorts of drugs - no company ever mentioned that they are working on something that would be practically
a salvation for humanity?
Edit:
" I don't necessarily mean "complete happiness". I don't even think it's possible because the point is that I also believe happiness is infinite, so we can never have a complete happiness in a sense of not being able to be more happy. The complete happiness I'm reffering to is the complete inner peace. And also that no matter what happens - it can never gets painful (besides basic survivale mechanisms, but the amount pain that people today expierience is not even near the needed to survive - e.g. on Oxy also feel enough physical pain to move away from something that my body is warning me against.). The whole point is there should only be inner peace with excitement as "additional" happiness or as "a carrot". And there should be (almost?) no stick (most of the time?) because it's presence is the interaption to the goal it should "bit you" towards.
The only logical sense of suffering and pain that beneficial is being more able appriciate your happiness when you have it. Which explained by the rubberband analogy: The more you put rubberband into the darkness, when you let it go into to the light (happiness) - the further it will go into that direction. But first we have to let it go sometime. "
"Yes, but having a complete inner peace (which I mean by complete happiness), wanting more would not be a problem. It would be like "I'm fully peaceful, at ease and content, but I want excitement (/more excitement) that's why I'm doing stuff that's excites me (probably mostly in the world as oppose to imagination). "
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