It doesn't feel as deep, or make me feel as fully immersed. Once I take a certain amount, I feel a very strong connection to something, but taking a low dose... It kinda makes me feel like I've got one foot in the next plane, which makes me feel a bit more anxiety and pay more attention to negative side effects. On a higher dose, I feel as though I've been pushed out far past the point of anxiety, especially during ego death, which is another reason I prefer high doses. Ego death is a major point of my use of psychedelics. Also, I don't get great visuals from doses under 250ug, which is probably just a personal thing. I get okay visuals, just nothing to write home about. The after effects seem to last longer with higher doses too.