Site Ki (nM) Species Ref
SERT 15–18 Human [12][13]
NET 1.8–4.4 Human [12][13]
DAT 1,140 Human [12]
5-HT1A 294 Human [14]
5-HT2A 5.0–41 Human/rat [15][14]
5-HT2C 8.5 Rat [15]
5-HT3 1,400 Rat [16]
5-HT6 148 Rat [17]
α1 55 Human [14]
α2 2,030 Human [14]
β >10,000 Rat [18]
D2 2,570 Human [14]
H1 3.0–15 Human [19][14][20]
H2 646 Human [19]
H3 45,700 Human [19]
H4 6,920 Human [19]
mACh 37 Human [14]
M1 40 Human [21]
M2 110 Human [21]
M3 50 Human [21]
M4 84 Human [21]
M5 97 Human [21]
σ1 2,000 Guinea pig [22]
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site.
You don't need any Clomipramine!! its very high binding to SERT! Add Nortryptyline to Zoloft!
Nort has been shown to help. It's more a Norepinephrine reuptake inhibitor than SERT so YES Neurologists and Psychiatrists use it for injuries to the Head of the Left Caudate nucleus, which causes severe Abulia and apaty.
I would def give that a shot!