You found lofexidine especially helpful? Much more than clonidine or tizanidine? Very interesting.
I know it's been around for decades as Britlofex etc, but it was very cynically introduced in the midst of the opiate epidemic as Lucemyra, "the only non-opioid FDA approved for detox" at the cost of hundreds of dollars for a 30-day supply... Versus <$10 for clonidine, which never got FDA approval for that purpose since it was already a generic in 1979 when they discovered its w/d effects (= nobody to pay for the research+process).
The only real advantage over clonidine that I heard about was less hypotension. Did you notice other things?