I can dedicate my life to studying premature ejaculation in Hamsters. That still doesn't make it a very worthwhile endeavor. If it's just a matter of personal curiosity, than I would definitely encourage you to pursue that and do it well. I'm not patronizing you at all. It's just that this definitely falls under the category of "hypothetical", because outside of the climax of a James Bond film, in which the SPECTRE is testing our metal and knack for statistics by asking us to determine who to save first, the Go-Go Dancer from the club scene earlier, dependent upon Methadone and Moneypenny, who is dependent upon Buprenorphine.
Why does said villain require such elaborate scenarios in which to conduct evil? Much like a gambling addict requires increasingly more extreme bets as their addiction progresses, simply hitting a pedestrian with your car and driving on or drowning a bag of kittens just doesn't cut it anymore.