Transcendence
Bluelighter
- Joined
- Jul 19, 2006
- Messages
- 2,505
I have treatment resistant depression and tried every available psychiatric option until only ECT or ketamine infusion were left. I've been receiving medically approved ketamine infusions on a regular basis from the best clinic in the U.S. It is expensive but effective.
I have deep suspicions that other related dissociatives may have a more pronounced ability to fight depression without the necessity of I.V. administration. Something that can be employed transdermally, sublingually, or as a nasal spray.
In my experience, 2F-ketamine is extrememely similar to ketamine. I would estimate about 10-20% less potent, with less pronounced psychedelia but a warmer afterglow and less residual mania. Downside is potency makes it nearly as inaccessible and impractical as prescription ketamine and probably as likely to induce bladder damage.
MXE was potent enough that nasal, oral, and sublingual use was very practical and interestingly led to very different experiences. It had an immediate antidepressant effect at least on par with 2F but unfortunately also more mania and very hard not to fall into recreational overuse and eventual psychosis. I am frankely amazed that nobody is taking advantage of the marketing monopoly considering U.S. legality and it would be a shame to lose this medicine forever.
MXM at 100mg was only practical orally and produced a short but indescribably wonderful psychedelic dissociative experience. It is the most psychedelic and mentally positive disso I've tried. If I could have an infinite supply of any recreational compound on earth it would be this short-lived and obscure jewel. Incredibly therapeutic and the ability to control visual and tactile hallucinations by thought alone. Short acting so that it could be used at night and not carry over into the next day. Although I mourne the unavailability of MXE, at least MXE was well explored and will always be remembered. MXM was only available for a couple months and I never hear it discussed. The most therapeutic and pleasurable and fascinating drug, I would rather mdma be lost to history than MXM. Oh well.
Everything else I've tried (oxo-pcm, oxo-pce, deschloro, 3meopcp, mxp, diphenidine, etc) has not been promising. The first three were bland/soulless mentally while being physically disabling for far too long. The likes of the latter three were too dark, unpredictable, and most of all psychotic to be used regularly.
Is there a arylhexamine I missed that approaches the medical potential of ketamine, 2F-ket, MXE or MXM?
I have deep suspicions that other related dissociatives may have a more pronounced ability to fight depression without the necessity of I.V. administration. Something that can be employed transdermally, sublingually, or as a nasal spray.
In my experience, 2F-ketamine is extrememely similar to ketamine. I would estimate about 10-20% less potent, with less pronounced psychedelia but a warmer afterglow and less residual mania. Downside is potency makes it nearly as inaccessible and impractical as prescription ketamine and probably as likely to induce bladder damage.
MXE was potent enough that nasal, oral, and sublingual use was very practical and interestingly led to very different experiences. It had an immediate antidepressant effect at least on par with 2F but unfortunately also more mania and very hard not to fall into recreational overuse and eventual psychosis. I am frankely amazed that nobody is taking advantage of the marketing monopoly considering U.S. legality and it would be a shame to lose this medicine forever.
MXM at 100mg was only practical orally and produced a short but indescribably wonderful psychedelic dissociative experience. It is the most psychedelic and mentally positive disso I've tried. If I could have an infinite supply of any recreational compound on earth it would be this short-lived and obscure jewel. Incredibly therapeutic and the ability to control visual and tactile hallucinations by thought alone. Short acting so that it could be used at night and not carry over into the next day. Although I mourne the unavailability of MXE, at least MXE was well explored and will always be remembered. MXM was only available for a couple months and I never hear it discussed. The most therapeutic and pleasurable and fascinating drug, I would rather mdma be lost to history than MXM. Oh well.
Everything else I've tried (oxo-pcm, oxo-pce, deschloro, 3meopcp, mxp, diphenidine, etc) has not been promising. The first three were bland/soulless mentally while being physically disabling for far too long. The likes of the latter three were too dark, unpredictable, and most of all psychotic to be used regularly.
Is there a arylhexamine I missed that approaches the medical potential of ketamine, 2F-ket, MXE or MXM?