I'm going to have to say simply smoking a nice big blunt.
That or some nice dxm and a blunt. It's like my mind is dead. I love it.
I don't do illegal drugs, they're dangerous
My fav ever combo is 1400mg soma + 40mg valium + a shitload of weed + beer.
Be prepared to fall over and pass out, but while it lasts it's verrrrrryyyy goood.