Agreed some can take a 5mg Ms contin and be high and others can take 1500mg and still walk around it doesn't even affect them but I have found some people cant even handle a panadine forte or 2 of them they are away with fairy's it's an impossible question harm reduction says start low and moove up so reseaçh the 1mgor 1 fast release being 1mg oral morphine to everything else opiate and opioids it will give you the conversions so you can make an educated guess but s5ill a guess but I'd you know you can take 8 panadine forte and it's equal to hypothetical 10mg oxynorm then you have an idea where to go or where you need may be with ms contin