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☠ WARNING ☠ *WARNING* Chronic ketamine/dissociative use causes bladder/organ damage

350 or 400mg (been years but it was in that range) of oral S-ket felt kinda like 100 - 150mg snorted but lasted a lot longer and felt totally different. Well not totally but it wasn’t clear-headed as S-ket snorted, felt a lot more bodily/opiodish in the body, didn’t put me into K hole but rather to sleep. If nor-ket was not harmful I would look upon as a drug remotely similar to ket but good.

I took too much because I thought it’s about 2x less potent than intranasal and it kinda is but it’s a whole different experience and sometimes in the future when I get it again, if I’ll ever have plenty I’ll surely try it orally again but cut the dose 2 or 3 times as 350 – 400mg orally was anesthetic dose even I had some tolerance and could easy do that much intranasal over duration of that oral experience. Didn’t felt damaging in any way but I know that doesn’t mean it isn’t, with many drugs it is the thing that it can feel harmless and do the most damage.
 
I’ve been using/abusing dissociatives for quite some time. I definitely could tell, upon heavy IV/IM ketamine usage, that it was putting some strain on my bladder. Significant urinary retention accompanied by frequent urination. Not a pleasant dilemma. My body feels like it’s trying to get rid of large amounts of urine, but the retention makes it very uncomfortable. When I’m able to overcome the retention, huge amounts of urine is excreted leaving me extremely dehydrated.

I’ve grown quite found of FXE lately and have been using it frequently. I find IV/IM FXE provides better effects than K. It’s slightly more potent, so it requires less material, and it last longer as well so I’m not redosing as much. Thus far I find it easier on the body. Is there something about the molecular composition of K that makes it’s particularly harder on your bladder? FXE is has the an ethyl amino group as opposed to a methyl amino group and the halogen is positioned on the 3-C phenyl ring. I have a fairly limited understanding in regards to organic and biochem. Does anyone have any insight on this matter?
 
So this is interesting because I’ve been reading people mostly saying that it’s harder on your bladder than normal k, but I’ve also been noticing that Fxe seems to be easier on my body that k
 
So this is interesting because I’ve been reading people mostly saying that it’s harder on your bladder than normal k, but I’ve also been noticing that Fxe seems to be easier on my body that k
I think all of the more potent RC dissociatives might be lighter on the bladder than ketamine because it isn't the NMDA antagonism itself which causes harm but something different about the arylcyclohexylamine structure (e.g. DXM afaik doesn't cause bladder problems at all).
 
Intranasal FXE did alot of damage to my sinuses and i have these terrible soars in them that are painful and became infected. Was doing about a gram a weekend for a few months and started developing this issue a couple weeks ago and it got progressively worse. Just saw a specialist today and they are definitely inflamed and infected bad.

He started me on oral and topical antibiotics and warned me stuff sniffing drugs before the damage is irreversible. Never had a problem like this from sniffing a disso before and ive been at this for a longtime. Personally im only going to be taking the stuff oral/sublingually once in awhile.

Its really uncomfortable and obviously having an infection like this close to the brain is very sketchy 😔
 
I strongly suggest that you don’t snort anything for at least a few month. Certain amount of damage you do to nose by snorting can be reversed but it takes a long time, sometimes more than 6 months. If you don’t take long breaks when sings of damage occur you can expect very bad outcomes sooner than later. And be sure to stop snorting at first signs of damage as when they occur that means your nose is already pretty fucked up. It might have to do something with FXE (or impurities in it) but snort enough sugar or whatever and eventually you’ll cause damage to your nose and sinuses. Ofc some people can are more some less sensitive to damage done by snorting per se.
 
What about DXM?
I've been on hundreds of DXM trips, but have only ever had my brain, heart & lungs checked out in the past year, which were all fine.
 
I strongly suggest that you don’t snort anything for at least a few month. Certain amount of damage you do to nose by snorting can be reversed but it takes a long time, sometimes more than 6 months. If you don’t take long breaks when sings of damage occur you can expect very bad outcomes sooner than later. And be sure to stop snorting at first signs of damage as when they occur that means your nose is already pretty fucked up. It might have to do something with FXE (or impurities in it) but snort enough sugar or whatever and eventually you’ll cause damage to your nose and sinuses. Ofc some people can are more some less sensitive to damage done by snorting per se.

Im not gonna snort any drug ever again honestly, this really fucked me up in the head honestly ive been so bugged out for the last week. Everytime i sniff a drug now its gonna give me so much anxiety. Honestly i feel like FXE in particular is really hard on the sinuses because i never had a problem with MXE/MXiPr/MXPr/DMXE/DCK/O-PCE/2F-DCK/Ketamine/3-MeO-PCE/3-HO-PCE/3-MeO-PCP and ive used all those intranasally mostly.

All the other dissos i used i had taken orally. This stuff just started doing damage to me, granted ive snorted a ton of Coke/Heroin in my life and all sorts of other designer drugs and pills so its deff from a lifetime of abuse as well. But this stuff has a definite burn to it when you do a lot and i was sniffing like 300mg+ in a couple lines for some doses, than topping up with less. And then going thru like maybe 1-1.5g's each weekend, so it was alot of powder.

Im pretty sure that was i have was highly pure it comes in huge solid rocks right from a wholesaler connected with the lab producing it. Im gonna just make a 500mgs capsule for now on and take that orally, its gonna be difficult to hole now on for sure but if i do n2O balloons with that on the peak i can probably get somewhere though.
 
I noticed damage to nose even from stuff that’s usually considered easy on the nose when I would snort big enough amounts.

I think most likely explanation to what happened to you is microscaring because of so much crystals snorted and that eventually let to infection. If I’m right it could have been prevented by dissolving it in minimal amount of water and spraying/squirting into the nose. But some other things beside microscaring could have played the role in snorting causing infection so who knows.

Maybe better switch to something more potent cuz of potential bladder issues?
 
I’m 28 years old and I started taking ketamine 19 months ago.
I used to take cocaine every Friday night through to Saturday morning and not touch a thing until the next Friday.
Then I discovered ketamine. Every single experience I’ve had on ketamine has been euphoric. It’s almost as if I have an epiphany after each usage. It’s absolutely brilliant in managing mental health.
However. After just a few weekends of taking ket literally probably just about 0.5 grams on a Friday.
It changed to a couple of days a week to every single day for 18 months of my life.
I went from making a teenth 1.75 grams lasting me 3/4 days to now 3.5grams a day some days.
Despite my depression improving because obviously ketamine is an escape from reality.
My stomach and bladder and pelvic floor muscles have been absolutely battered.
I used to get regular UTI’s when I first started heavily taking it. I’d just mask the pain with more ket and ignore it. However in October last year I developed mild gastritis and ketamine cystitis.

They both always manage to flare up together aswell which makes each experience 100 times worse.
The cystitis would last for around 3 weeks at the start and I would sniff ketamine to avoid the pain until it became completely unbearable then I’d take opioid medications to ease the pain which lead to chronic constipation and feacial impaction. This was reoccurring every month because I refused to stop after suffering a very close bereavement and ongoing abuse from my ex partner.

I was refered to a urologist I havnt been honest with them as to why I get the cystitis but I think it’s time to make them aware. I had a cystoscopy done in early February. I found out I had a urethral stricture (narrow urethra) this was caused by the frequent utis and cystitis. They performed a urethral stretch which actually helped. I hadn’t had a flare up for 2 months. Despite continued ketamine abuse.

However. On the 4th of April I started with urethral pain again. I knew the urethra had shrunk again but I continued to take ketamine for the pain. Then I got a chronic uti which wouldn’t budge despite having 5 different anti biotics which obviously has now turned to cystitis. I’m currently on my 4th week of ketamine cystitis and this is the worst it has ever been. I have my results for my cystoscopy next week by the sounds of things my bladder was okay. But this time it’s different I have a sharp pain in my pelvic area and the burning from the urethra is terrible I never usually get this burning pain. My bladder is soasaming and so is my urethra. I can’t walk for longer than 5 mins without setting off a flare. I think I may have ulcers on the bladder and maybe urethral lesions. Now because I’m in pain I’m back on opioids and I have chronic constipation but because I can’t push without setting off extreme pain with my bladder and urethra I’m stuck.
My bladder is also slightly prolapsed too due to poor pelvic floor muscles from constipation and from the constant urge to push urine out which comes with ketamine cystitis.

I’m at my whits end with it and I need some relief. Does anybody have any suggestions I’ve seen the green tea but this aggravates my gastritis.
I would like to put forward that I have just started useing an over the counter pain killer specifically for UTIS called azo and it has worked wonders. However it’s damaging on my gastritis so no doubt I’ll have to stop them very soon. The morphine isn’t even touching the sides this time round.

I would like to mention I havnt taken ketamine now for 8 days. I’m so proud of myself because this is the first time in a very long time I’ve been sober. Normally I only last 2 days abstinence from it but I’ve stuck it out. I honestly never want to touch it again I’m so petrified. I’m really hoping the fear is enough to end my addiction.

I am going to try CBD oil or CBD vapes when I can get my hands on one because it’s supposed to have benefits to the bladder.

I’ve also read that a teaspoon bicarbonate soda in a glass of water and drink the full drink acts as a natural anti inflammatory and is great for UTI pain relief. So I’m going to ask a friend to grab me some from the shop tomorrow.

Please please please do not fall into the ketamine trap. Despite it feeling good when you’re depressed you just remember it is only a partial escape. Masking problems with maladaptive behaviours, addictions and distraction are detrimental to your mental health. Since having this flare up I’ve had the most suicidal thoughts I’ve ever had in my life. Your physical health matters too much to be gambling with especial when you suffer mentally.
Every single drug abuser suffers mentally. There isn’t a single person who wakes up in the morning craving an escape from their reality in the form of an illicit substance that isn’t a sufferer of some sort of mental health. The average joe doesn’t take drugs. Even if it’s just a weekend thing wanting to escape in itself is a mental illness even if you don’t realise it.

So In all due respect compassion and understanding is needed. I love these threads because I get to see the side of the world who isnt so judgmental. Addiction is the biggest illness in the world and is by far the worse because the world doesn’t see it as a disease they see you as selfish, vulgar and like you’re making the choice to carry on off your own back. Drugs flip an irreversible switch in your brain.

I got to my third year in uni last year with social science I wanted to be a physiologist however my addiction stopped me achieving it. The cystitis caused me to miss so much. So I’ve made a promise to myself now I no longer want to engage with drugs.

I want to become a mental health and drug advocate specifically for ketamine use. I’ve noticed how many young people are taking it regularly and it’s so scary. These kids are going to be with catheters before they’re 20 and society are just going to look at them like scum. I’ve always wanted to make a difference in peoples lives and this way I can with my own experience and knowledge of that specific situation.

Wish everybody the best and good health I hope those still choosing to take ketamine are extremely careful. I hope those willing to stop find the will too. I hope those on the recovery path understand it will eventually be easier you’ve just got to find a purpose :)
 
Im not gonna snort any drug ever again honestly, this really fucked me up in the head honestly ive been so bugged out for the last week. Everytime i sniff a drug now its gonna give me so much anxiety. Honestly i feel like FXE in particular is really hard on the sinuses because i never had a problem with MXE/MXiPr/MXPr/DMXE/DCK/O-PCE/2F-DCK/Ketamine/3-MeO-PCE/3-HO-PCE/3-MeO-PCP and ive used all those intranasally mostly.

All the other dissos i used i had taken orally. This stuff just started doing damage to me, granted ive snorted a ton of Coke/Heroin in my life and all sorts of other designer drugs and pills so its deff from a lifetime of abuse as well. But this stuff has a definite burn to it when you do a lot and i was sniffing like 300mg+ in a couple lines for some doses, than topping up with less. And then going thru like maybe 1-1.5g's each weekend, so it was alot of powder.

Im pretty sure that was i have was highly pure it comes in huge solid rocks right from a wholesaler connected with the lab producing it. Im gonna just make a 500mgs capsule for now on and take that orally, its gonna be difficult to hole now on for sure but if i do n2O balloons with that on the peak i can probably get somewhere though.

You remember asking me why I did K sublingually now… This is why brother ❤️

-GC
 
I’ve been using/abusing dissociatives for quite some time. I definitely could tell, upon heavy IV/IM ketamine usage, that it was putting some strain on my bladder. Significant urinary retention accompanied by frequent urination. Not a pleasant dilemma. My body feels like it’s trying to get rid of large amounts of urine, but the retention makes it very uncomfortable. When I’m able to overcome the retention, huge amounts of urine is excreted leaving me extremely dehydrated.

I’ve grown quite found of FXE lately and have been using it frequently. I find IV/IM FXE provides better effects than K. It’s slightly more potent, so it requires less material, and it last longer as well so I’m not redosing as much. Thus far I find it easier on the body. Is there something about the molecular composition of K that makes it’s particularly harder on your bladder? FXE is has the an ethyl amino group as opposed to a methyl amino group and the halogen is positioned on the 3-C phenyl ring. I have a fairly limited understanding in regards to organic and biochem. Does anyone have any insight on this matter?
What is FXE?
 
definitely give your nostrils a break if it gives you warning signs. For me, it would get plugged up and stay that way for at least 24h after, no matter how much allergy meds or saline solution applied. I gave my nose a break for a couple months and now their are no issues. Definitely reducing the frequency of usage however.
 
FXE is Fluorexetamine. It’s just another arylcyclohexamine derivative/analogue that possesses some qualities similar to that of ketamine. I find it to more stimulating, clear headed, and warmer than K
Do you still get bladder problems from it? I’ve never heard of it. Im from uk. North west. We probably don’t get it down here
 
350 or 400mg (been years but it was in that range) of oral S-ket felt kinda like 100 - 150mg snorted but lasted a lot longer and felt totally different. Well not totally but it wasn’t clear-headed as S-ket snorted, felt a lot more bodily/opiodish in the body, didn’t put me into K hole but rather to sleep. If nor-ket was not harmful I would look upon as a drug remotely similar to ket but good.

I took too much because I thought it’s about 2x less potent than intranasal and it kinda is but it’s a whole different experience and sometimes in the future when I get it again, if I’ll ever have plenty I’ll surely try it orally again but cut the dose 2 or 3 times as 350 – 400mg orally was anesthetic dose even I had some tolerance and could easy do that much intranasal over duration of that oral experience. Didn’t felt damaging in any way but I know that doesn’t mean it isn’t, with many drugs it is the thing that it can feel harmless and do the most damage.
Ive only tried eating or plugging ket a few times.
Once i took my last 0.5g and snorted a line and ate the rest before a airplane to India..

Didnt get much out of it though, def felt a nice buzz for a few hours.
Better then tossing it in the trash.
 
Just a warning, to anyone considering starting IM/IV ketamine use be very careful. If you were a fiend before and have easy access it's game over once you start. Takes a long time to work your way out.

Yeah IM ket is a beast if you get sucked into the crazyness.
 
I’m 28 years old and I started taking ketamine 19 months ago.
I used to take cocaine every Friday night through to Saturday morning and not touch a thing until the next Friday.
Then I discovered ketamine. Every single experience I’ve had on ketamine has been euphoric. It’s almost as if I have an epiphany after each usage. It’s absolutely brilliant in managing mental health.
However. After just a few weekends of taking ket literally probably just about 0.5 grams on a Friday.
It changed to a couple of days a week to every single day for 18 months of my life.
I went from making a teenth 1.75 grams lasting me 3/4 days to now 3.5grams a day some days.
Despite my depression improving because obviously ketamine is an escape from reality.
My stomach and bladder and pelvic floor muscles have been absolutely battered.
I used to get regular UTI’s when I first started heavily taking it. I’d just mask the pain with more ket and ignore it. However in October last year I developed mild gastritis and ketamine cystitis.

They both always manage to flare up together aswell which makes each experience 100 times worse.
The cystitis would last for around 3 weeks at the start and I would sniff ketamine to avoid the pain until it became completely unbearable then I’d take opioid medications to ease the pain which lead to chronic constipation and feacial impaction. This was reoccurring every month because I refused to stop after suffering a very close bereavement and ongoing abuse from my ex partner.

I was refered to a urologist I havnt been honest with them as to why I get the cystitis but I think it’s time to make them aware. I had a cystoscopy done in early February. I found out I had a urethral stricture (narrow urethra) this was caused by the frequent utis and cystitis. They performed a urethral stretch which actually helped. I hadn’t had a flare up for 2 months. Despite continued ketamine abuse.

However. On the 4th of April I started with urethral pain again. I knew the urethra had shrunk again but I continued to take ketamine for the pain. Then I got a chronic uti which wouldn’t budge despite having 5 different anti biotics which obviously has now turned to cystitis. I’m currently on my 4th week of ketamine cystitis and this is the worst it has ever been. I have my results for my cystoscopy next week by the sounds of things my bladder was okay. But this time it’s different I have a sharp pain in my pelvic area and the burning from the urethra is terrible I never usually get this burning pain. My bladder is soasaming and so is my urethra. I can’t walk for longer than 5 mins without setting off a flare. I think I may have ulcers on the bladder and maybe urethral lesions. Now because I’m in pain I’m back on opioids and I have chronic constipation but because I can’t push without setting off extreme pain with my bladder and urethra I’m stuck.
My bladder is also slightly prolapsed too due to poor pelvic floor muscles from constipation and from the constant urge to push urine out which comes with ketamine cystitis.

I’m at my whits end with it and I need some relief. Does anybody have any suggestions I’ve seen the green tea but this aggravates my gastritis.
I would like to put forward that I have just started useing an over the counter pain killer specifically for UTIS called azo and it has worked wonders. However it’s damaging on my gastritis so no doubt I’ll have to stop them very soon. The morphine isn’t even touching the sides this time round.

I would like to mention I havnt taken ketamine now for 8 days. I’m so proud of myself because this is the first time in a very long time I’ve been sober. Normally I only last 2 days abstinence from it but I’ve stuck it out. I honestly never want to touch it again I’m so petrified. I’m really hoping the fear is enough to end my addiction.

I am going to try CBD oil or CBD vapes when I can get my hands on one because it’s supposed to have benefits to the bladder.

I’ve also read that a teaspoon bicarbonate soda in a glass of water and drink the full drink acts as a natural anti inflammatory and is great for UTI pain relief. So I’m going to ask a friend to grab me some from the shop tomorrow.

Please please please do not fall into the ketamine trap. Despite it feeling good when you’re depressed you just remember it is only a partial escape. Masking problems with maladaptive behaviours, addictions and distraction are detrimental to your mental health. Since having this flare up I’ve had the most suicidal thoughts I’ve ever had in my life. Your physical health matters too much to be gambling with especial when you suffer mentally.
Every single drug abuser suffers mentally. There isn’t a single person who wakes up in the morning craving an escape from their reality in the form of an illicit substance that isn’t a sufferer of some sort of mental health. The average joe doesn’t take drugs. Even if it’s just a weekend thing wanting to escape in itself is a mental illness even if you don’t realise it.

So In all due respect compassion and understanding is needed. I love these threads because I get to see the side of the world who isnt so judgmental. Addiction is the biggest illness in the world and is by far the worse because the world doesn’t see it as a disease they see you as selfish, vulgar and like you’re making the choice to carry on off your own back. Drugs flip an irreversible switch in your brain.

I got to my third year in uni last year with social science I wanted to be a physiologist however my addiction stopped me achieving it. The cystitis caused me to miss so much. So I’ve made a promise to myself now I no longer want to engage with drugs.

I want to become a mental health and drug advocate specifically for ketamine use. I’ve noticed how many young people are taking it regularly and it’s so scary. These kids are going to be with catheters before they’re 20 and society are just going to look at them like scum. I’ve always wanted to make a difference in peoples lives and this way I can with my own experience and knowledge of that specific situation.

Wish everybody the best and good health I hope those still choosing to take ketamine are extremely careful. I hope those willing to stop find the will too. I hope those on the recovery path understand it will eventually be easier you’ve just got to find a purpose :)
Thank you very much for sharing your challenging path. I‘m 33 and have almost the same story to tell.

I always loved to party hard on psychedelics and loved deep holing with K during LSD trips or after raves. During my mid 20‘ies I raved too hard on MDMA (every weekend) and screwed myself a little bit up - luckily I was able to stop before it became too bad with my stress/anxiety issues and I wasn’t really up with K at that time.

I quit, for a while, became the best version of myself… and then covid happened + relationship broke up. I am generally ultra healthy, used to have real abs (6 month ago) and my general physical condition was just absolutely impressive.
There was a friend who told me he has 20g K and I bought 10. I knew I liked K but being totally locked down and no GF to deal with, made me fall in love with K at that time.

In the beginning it was -for sure- only on weekends (100-150mg) but that didn’t last long. Pretty soon I found out that housework, walks and meditation became SOO much more enjoyable/powerful with just a tiny nose of K (maybe 20-50mg) and I started to use it regularly under the week.

I paused when I thought it became too much and frequent after a while… but never more than 4 weeks. Someday I found out that banging me down into the hole after a heavy gym workout to instantly relax, made me even more motivated going into the gym almost every day. It was impressive: I never, ever felt so good in my life, had the best physical and mental condition I ever had and everything was 110%.


After doing this on-and-off for 1.5 years (consumed 15g in total), someday I realized a little tension in the pelvic area. Not much, no pain, but annoying. I thought it had something to do with my bowel, but quit using K to be sure. That was December 2021. It was gone after some days and I stopped using K for about 4 weeks which made all symptoms go away. I did some research during this episode and found out the first time about Ketamin related bladder issues, but I took K now and then until May 2022 when I first told me: STOP.


But the feeling of K pulled me back and I was still addicted so I wanted to try it out again, just to proof myself that its not from the K or I can deal with the “little” discomfort from time to time.
Sure, I felt discomfort immediately… paused a month or two and tried it another time. But again, discomfort and itchy feelings around the bladder. I was sure now that it was K, so I quit October/November 2022.

I found a new girl then, new job and life turned out to be quite nice even without K. But then… without using K for 3 months and not having issues, it started somehow around mid-February when I felt real pain in the bladder and kidneys. REAL pain so I went to the hospital and asked for help, told the Dr. that I abused K previously but he said, that he doesn’t believe it has something to do with it. Blood and urin analysis were super clean and probably because my overall health condition: he told me that I made things up in my head and it’s just bowel… I shouldn’t be worried and eat healthier. Two weeks later, I visited an urologist, told him about my K abuse and the problems I have. He was surprised, urin was clear and ultrasonic showed nothing as well. He said, it’s all fine, I shouldn’t do K. Two weeks later, I visited a different urologist and got the exact same diagnosis: all fine, there is nothing we can do - it will go away.

Two weeks later I visited my general Dr., was honest and got handed over to the emergency room at a hospital because bowel infection. I went there for sure, was honest about my history, but they didn’t perform cystoscopy or MRI and I was sent home without any diagnosis. I was told to make a bowel screening - what I did (all fine… lol).

After another 4 weeks… symptoms became worse and worse, I went to a specialized urological clinic and was honest again. The first Dr. told me, better not to tell anything about my drug abuse but sent me to their emergency department where they did nothing besides urin analysis and ultrasonic (lol) which revealed nothing.
I asked for cystoscopy but they said, they don’t believe it is coming from the bladder so they won’t perform it and I got two different antibiotics that didn’t help at all.

So, being unable to live my life because of serious pain episodes since Feb 2023, can barely deal with work, lost my new girlfriend, lost my shape and visited several Drs:

6 different Drs, 3 urologists, 3 times hospital (2x emergency), bowel screening and I was honest with everyone… can’t be true and I ask for cystoscopy or any other help, but they don’t.

I eat super healthy, drink tons of water and tea, no alcohol or other drugs besides Cannabis, spent 250€ on supplements like omega3, hyaloron, chondroitin, glucosamine and so on. I believe it has become a little better now since 1 week (I got a prostate pill 10 days ago that relaxes the muscles in the bladder and urethra). I have printed out two case studies and a medication (hyaloron acid + chondroitin sulfate - this will be injected directly into the bladder), for the next time I will visit my urologist after the MRI.
I hope he is open minded or does something else that helps me!

It’s so frustrating, even ChatGPT seems to be a better Dr than all of the 6 I have talked to. Ask: “pelvic pain ketamin”…

Tomorrow I have finally MRI. Next time I will see the Dr will be hopefully on Thursday. Keep you updated.

Sorry for my English, I am a german kartoffel.

Research studies:
 
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hey guys, thought I share a little update:

MRI was made and it did not show any bladder wall thickening or something else - Dr tells me all good, again.
I had to insist on getting help, pulled out the printed case studies but the only thing he said was: “do you really think it’s coming from the drugs?”

I said, yes, but if its not… thats fine for me too, but he should please help me to end this nightmare.

Instead of performing a cystoscopy in his premises he prescribed a cystoscopy + bladder biopsy at the hospital where I have an appointment to discuss this.

…Since then (4 Weeks ago) I’m still dealing with intense chronic bladder pain every day… Next appointment will be in two weeks.
 
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