slimvictor
Bluelight Crew
- Joined
- Dec 29, 2008
- Messages
- 6,483
Increasing exposure to vaccine antigens in the first 2 years of life was not associated with the development of an autism spectrum disorder (ASD), researchers found.
After adjustment for potential confounders, the odds ratios for ASD for each 25-unit increase in total antigens were 0.999 (95% CI 0.994 to 1.003) for exposure up to age 3 months, 0.999 (95% CI 0.997 to 1.001) for exposure up to age 7 months, and 0.999 (95% CI 0.998 to 1.001) for exposure up to age 2 years, according to Frank DeStefano, MD, MPH, of the CDC's Immunization Safety Office in Atlanta, and colleagues.
Antigen exposure also was not associated with autistic disorder or ASD with regression, defined as the loss of previously acquired language skills among those with the disorder, the researchers reported online in the Journal of Pediatrics.
"These results indicate that parental concerns that their children are receiving too many vaccines in the first 2 years of life or too many vaccines at a single doctor visit are not supported in terms of an increased risk of autism," DeStefano's group wrote.
Furthermore,"the possibility that immunologic stimulation from vaccines during the first 1 to 2 years of life could be related to the development of ASD is not well supported by the known neurobiology of ASD, which tends to be genetically determined with origins in prenatal development, although possible effects in early infancy cannot be ruled out completely," they wrote.
cont at
http://www.medpagetoday.com/Pediatrics/Autism/38165
After adjustment for potential confounders, the odds ratios for ASD for each 25-unit increase in total antigens were 0.999 (95% CI 0.994 to 1.003) for exposure up to age 3 months, 0.999 (95% CI 0.997 to 1.001) for exposure up to age 7 months, and 0.999 (95% CI 0.998 to 1.001) for exposure up to age 2 years, according to Frank DeStefano, MD, MPH, of the CDC's Immunization Safety Office in Atlanta, and colleagues.
Antigen exposure also was not associated with autistic disorder or ASD with regression, defined as the loss of previously acquired language skills among those with the disorder, the researchers reported online in the Journal of Pediatrics.
"These results indicate that parental concerns that their children are receiving too many vaccines in the first 2 years of life or too many vaccines at a single doctor visit are not supported in terms of an increased risk of autism," DeStefano's group wrote.
Furthermore,"the possibility that immunologic stimulation from vaccines during the first 1 to 2 years of life could be related to the development of ASD is not well supported by the known neurobiology of ASD, which tends to be genetically determined with origins in prenatal development, although possible effects in early infancy cannot be ruled out completely," they wrote.
cont at
http://www.medpagetoday.com/Pediatrics/Autism/38165