Hey guys just wondering is there any way to upregulate the "α2-δ subunit of voltage-dependent calcium channels" that are mostly involved in phenibut. I know people use fasoracetam to upregulate GABA-B however I have seen some threads that tolerance to phenibut is not just GABA-B especially that the affinity is not as strong for the GABA-B receptor. I also noticed some people had success with agmatine to potentiate phenibut.