Tune your mind and body
To clarify experience on this subject, iveused sas/mda about 6 different times and used higher does than this before. Ive just never combined it with lsd before now. So i am aware of the risks but i am also aware of what my body is capable of handling from experience. I would not recommend mda to anyone who cant handle mdma at higher doses. You most definantly will throw up and put yourself at risk. From everyones feedback i will for sure be more educated on the potency of hallucinogins before doing it again.
Learn to be sensitive. It does not take a lot of 25 to generate a decent buz for most people if you are not taking it daily. Mda tends to neutralize your ability to get any positive benefit if you take it more than 2 days in a row or 2x in one day without a break to recover so just time your fun within the limits.
Try to let your body chemistry find out what normal feels like and then start with something smaller. Whatever that is just let it be for the duration and if it was short of what you were looking for give it a break to let things return to normal and then adjust.
It is not some contest or a crown or trophy event to claim you take more of something than someone else does. Learn to appreciate fine quality instead of believing that more is better. The more is better concept kills fun and kills people.
More consumption than needed is just wasteful and costly in terms of money and health.
Unless you are a master chemist or unless you have sent multiple samples in for analysis there is really no way to know what amount you are consuming so when you jump above what the manufacturer targets as a normal dose you are more likely to be one of those statistics.
At the very least you will find yourself the topic of discussions about people who yelled insanely while intoxicated on an unknown quantity of a combination of street drugs. That eventually gets old as people begin to avoid you and count you out whenever something is going on.
There is no reason to overdose on street drugs. It is basically less than intelligent behavior.
If you feel a reason to experiment with unusually high doses of street drugs you should look into finding a career in a research business where the non prescription drugs are manufactured under controlled circumstances and dosed at known levels. You could be a test subject and have doctors and nurses standing by to save your life when you consume past the limit of your body to process the poison.
Paranoia on 25 is common in people who are not comfortable with themselves as is extreme dosing behavior.
People who are comfortable with themselves and are in a comfortable situation and feel relaxed and confident and are not daily drug abusers typically just feel good about everything they do.
I have known people who did nothing but laugh for 10 hours on doses as small as 50 mics or as high as 400 who were not daily abusers. Over 4 in a clean body of a typical size person can be a little in a different direction than laughter but still typically should not lead to paranoia in a person who is comfortable and confident and is not in some hostile or otherwise bad situation.
Last comment. Mixing good MDA with anything else is just a waste of a good dose.
Death is a reality but so are kidney, liver, or other organ failure and all sorts of other extremely undesirable side effects.
Your life will be horrible if you don't play by the rules with potentially toxic substances.
I knew a guy who talked like you write about 40 years ago. He was blinded by a dose error by the time he was 20 and spent the rest of his life wandering around in darkness and being led by the hand everywhere he needed to go. What fun is that?