That's helpful. One of the common mistakes with DOx is taking booster doses prematurely, which faster ROAs would address. I'd still be leery with the strongly stimulating and strongly psychedelic ones, as a rapid comeup might be anxiogenic and confusing (although alleviating some of the come-up discomfort could be nice.)
With some of the apparently less stimulating or deep DOx like DOF, it might be worth exploring faster ROAs, particularly for dosage work ups when getting one's feet wet and starting very low. The more rapid onset might make the headspace change of these subtler chemicals more profound if the onset is faster, providing less time to acclimate to the space. Just knocking an hour off of the come-up and an hour off of the duration might make it easier to work with the material, as well. Insufflation seems less practical than rectal ROAs for DOx in the low mg potencies unless people have sensitive lab balances available. Vaporizing/nebulizing, though, might still be reasonably practical, because of the ease of titration and the speed of onset. Now you have me curious.