Merged a few threads together into a central one. I have not really spent time digging and researching but I haven't heard about anyone trying 2C-H with a MAOI yet... (I think theoretically a MAO-B-I is what would be best if it were true that 2C-H can be activated like DMT?)
If you piece together hints people are giving you can easily see how they are warnings against adverse reactions. The mentioned hypertensive crisis could be caused by adrenergic activity running wild or more generally speaking by dangerous sympathomimetic action (if I am getting that right). If I recollect Erny saying that the NBOMe analogue is uneventful at low doses and frightening or stressing at higher 'active' doses. Of course that is another compound but with MAOIs as part of the scheme it is notoriously tricky to inhibit metabolism without making your nervous system defenseless to an assault by the compound.
(Perhaps it is not relevant here but I found mushrooms & MAOIs to feel exactly like that: like I had no chance to stand up to it. Of course as a rule it is best to let yourself go during a trip but being forced to is sometimes called something like soul rape if it is overwhelmingly psychedelic/spiritual/entheogenic. With a stimulating compound disinhibition would go more into directions of terror, panic, in other words anxiety through the roof, hypertension, possible cardiovascular issues - a state that can easily lead to complications).
I don't wanna make anyone shit their pants without proof that this will happen, but I think these are reasons why perhaps even being careful wouldn't cut it but only meticulous very slow titration of doses... if that. The therapeutic index or dose-response curve might be that steep. So needless to add I recommend against the idea and the payoff just doesn't seem to be worth it, just looking at receptor affinities or lack thereof. Even in the unlikely event that you find a novel way of stimulant use, the dangers would still make it useless.
Hmmm what receptors
does 2C-H interact with by the way, is that known?
Shulgin's psychedelic index is only of little help, directing me to this article:
http://jpet.aspetjournals.org/content/321/3/1054.full
I think it doesn't say that 2C-H does absolutely zero to the serotonin receptor, for 5HT2C (not psychedelic) instead only one of two 'activation pathways' is triggered. But what is interesting is that 2C-N also triggers only one pathway namely the other one. So... if 2C-N and 2C-H are taken together in the right doses might one expect significant 5-HT2C effects? Or do the signal transduction pathways necessarily have to be triggered by the same compound... like for timing or something more sophisticated as my description?
Anyway I think the wrong thing would happen with the 5HT2C. It is associated with anxiety I think, and I really doubt that 2C-N + 2C-H will switch that to the right direction! So maybe 2C-N + 2C-H is actually very bad news.