Lorne???
Bluelight Crew
- Joined
- May 3, 2014
- Messages
- 2,558
Nalaxone has no effect except blocking opioid receptors; Flumazenil is similar in regard to benzodiazepines
Get your point, your being a bit hyper technical though. And benzodiazepines DO have different effects; yes, 5 or 10 Xanax bars and ~100mg Valium will have benzo solid effects(unless you have a high tolerance)
Honestly, alprazolam is always fast acting and calming, and clonazepam helps my jerks and Lorazepam is neutral(and have high tolerance)
And most benzos don’t have relevant metabolites(Tranxene is almost completely converted presystemically to Nordazepam, and a couple of others, Librium think)
Onset, Tmax, Lipophillicty and actual DURATION OF ACTION are at top; T1/2, and metabolism (and yes, metabolites) are second.
And of course, dose ranges, like SDU(Standard Dosage Unit) and maybe typical doses.
Thanks for clarification and help
Get your point, your being a bit hyper technical though. And benzodiazepines DO have different effects; yes, 5 or 10 Xanax bars and ~100mg Valium will have benzo solid effects(unless you have a high tolerance)
Honestly, alprazolam is always fast acting and calming, and clonazepam helps my jerks and Lorazepam is neutral(and have high tolerance)
And most benzos don’t have relevant metabolites(Tranxene is almost completely converted presystemically to Nordazepam, and a couple of others, Librium think)
Onset, Tmax, Lipophillicty and actual DURATION OF ACTION are at top; T1/2, and metabolism (and yes, metabolites) are second.
And of course, dose ranges, like SDU(Standard Dosage Unit) and maybe typical doses.
Thanks for clarification and help