Agonizing of serotonin receptors is one of the many reasons that causes eyes to dilate. HPPD isn't really rewiring of the brain. One theory is that a process in the perception part of the brain called sensory gating is disrupted. Sensory gating is the brain "filtering" out excess or redundant information coming in. For instance people that are Schizophrenic have sensory gating problems which is probably why LSD and other psychedelics mimic Schizophrenia symptoms. Also, since HPPD fades over time it's more likely saturation of the serotonin receptor sites that deal with vision. But, as with most information about the brain and psychedelics this is all theory and rational speculation.
Interesting hypothesis. A lot of my HPPD symptoms from 2c-i was like a very mild - non deadly Serotonin syndrome.
Excessively locked muscles over 2 years
Over active reflexes, that would make me and my motor control very jumpy
Tremors, that would start after 10 minutes of waking up - this is completely absent of any anxiety.
Muscles locking up, when going to talk sometimes the muscles wouldn't be released and beginnings of sentences would come out sharp and forceful.
Luckily, the HPPD is finally disappearing, and I feel like I'm left with an permanent increase in dopamine and norepinephrine - which I can maintain at full rate all day with a L-Tyrosine supplement. I've never had such a extensive working memory, I can hold 10-15 thoughts or responses to someones discussion in my head, and call them in any order I want when replying to people. The increase in mental bandwidth and analysis is similar to the benefits while on 2c-i. It's been a weird and at times scary road, thinking the bad effects were permanent, but now I'm much better off than ever taking 2c-i. For my whole life I had to take stimulants to read or write for my ADHD, since my half year of taking 2c-i, 7 times, I have the mental bandwidth of a 35mg dose of ritalin without any of the stimulant side effects. I am more productive and can write better than I ever could on ritalin and I don't feel burnt out like being on ritalin.
I've heard of others say that Mescaline use fixed their ADHD. I wonder if it is something with the phenethylamine family - specifically those that deal with Dopamine and Norepinephrine which are the neurotransmitter pathways that the 2 main types of ADHD medicines target.
---- These are the symptoms I had for 2 years before it started dying down and getting back to normal. ---
1) Clonus / Myoclonus / Spontaneous clonus (from the Greek for "violent, confused motion") is a series of involuntary muscular contractions and relaxations. Unlike the small, spontaneous twitching known as fasciculations (usually caused by lower motor neuron pathology), clonus causes large motions that are usually initiated by a reflex.
2) Hyperreflexia is defined as overactive or overresponsive reflexes. Examples of this can include twitching or spastic tendencies
3) Muscle tremors
4) Hypertonia is a condition marked by an abnormal increase in muscle tension and a reduced ability of a muscle to stretch.. Rigidity is a state of hypertonia where muscle resistance occurs throughout the entire range of motion and is independent of velocity (whereas spasticity is velocity-dependent). People with rigidity present with stiffness, decreased functional ability and flexibility. There are two main forms of rigidity: leadpipe and **cogwheel**. With leadpipe rigidity, resistance from the muscle(s) remains throughout the entire range of movement and it is not velocity-dependent.[3] When rigidity is present with Parkinson's disease it is often termed as cogwheel. Cogwheel rigidity is a hypertonic state with rachetlike movements, and is believed to be present when rigidity and tremor occur together. Furthermore, the muscle(s) that have rigidity will not return to a fixed position after taken through range of motion[4]
