FrogWarrior
Bluelighter
- Joined
- Nov 10, 2013
- Messages
- 154
I forgot to say that I'm a beginner, I've done dissociatives maybe 20 times in total. PCP, MXE, ket, DXM, they all mind fuck me beyond all recognition. Diphenidine was so strange though, it seemed distinctly different to the other ones. Have you ever tried adding something to make it stranger, like say subbreakthrough doses of DMT or salvia (or both)? Iboga is a mind boggler too, but I'd avoid that since it seems to interact dangerously with all kinds of substances. Subbreakthrough doses of salvia alone gives me a pretty large mindfuck. Smoking a bit of salvia while on dissociatives would be sure to add enhance the strangeness of it.
BTW why go orally and not insufflation? I tried vaping and it seems to work but I start wheezing (asthma) and need to use a salbutamol inhaler so I think vaping is a bad idea in terms of lung health especially since you need such large amounts of it. You mentioned getting an idea of what a stroke is like. I've overdosed on GHB/GBL a few times, and experienced what ischemia induced cognitive impairment is like. The worst overdose I had (5g or GHB followed by 1mL of GBL, I went to sleep and woke up an hour later feeling violently ill), I had no idea what was going on or why I was feeling so sick, I couldn't remember the way around my own house. It wasn't fun (mainly because of how sick I felt). In less extreme cases like the other day after diphenidine I simply can't think in ways that I usually can. Its not very interesting, just a bit frustrating. Although its interesting to see it occur due to blocked NMDA receptors as opposed to ischemia. The most extreme case of this I experienced was on a salvia breakthrough, I couldn't remember who I was or where I had come from, I felt like I should be able to remember where I came from but all attempts to do so failed because there was a blockage in my ability to think about it, now that was interesting. Interestingly, it says on the wiki page that diphenidine was researched for its potential to treat stroke related brain damage. Piracetam is also used for this, from what I read piracetam if administered within a short time window after the stroke occurs prevents a large percentage of the long term damage from occuring. Whats interesting there is piracetam enhances glutamate activity rather than blocks it. I believe piracetam works on AMPA receptors (its a positive allosteric modulator) though, not NMDA receptors.
EDIT: Actually no, I put DXM in my list of mind fucking dissociatives but I've never got a profound mindfuck from that. The highest dose I did was 500mg and at its peak I felt a sudden wave of panic and dread come over me, but no dissociative effects. My experiences with DXM were mildly trippy at most. DXM seems to be in a class of its own, it feels nothing like PCP or diphenidine to me. With diphenidine there was no panic, just this profound weirdness, at its peak my body went on auto pilot its like I was possessed (not in a bad way), my body was performing this task in sync with my brain, that was just after I posted about God being 0 in that live trip report on the shroomery. Mind you, I took etizolam before hand, that always nullifies any fear and panic so maybe this woulda been scary if I wasn't on etizolam. Maybe the etizolam even added to the effects, GABA drugs can cause mind fuckery of their own, zolpidem gives me waking dreams sometimes, and I haven't tried Amanita muscaria yet but I believe it works as a GABA_a agonist. Psychedelic benzo modulated GABA effects only seem to apply to z-drugs though, not the less selective BZ agonists as far as I know.
Anyhow, I'm derailing the hell out of this thread, so I'll shut up now. Looking forward to reading about your trip report with 180mg.
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I wouldn't even have thought of that. I didn't even have to put any dmt into my pipe, seems there was plenty left in it for me to enter hyperspace. very smooth transition, everyone was there! 
