Did anyone try Fly with Rilmenidine?
Here's a Shulgin note on it:
8.0 mg 2C-B-fly and 2.0 mg of rilmenidine at 12:30 pm; cannabis vapor at 4:00:
The result was spectacular. I got a +4 experience from a pure imidazoline blood pressure
medication! It is probably the entactogenic core of MDMA. I tend to think of the effects
of MDMA as sweeter and gentler than this, but this was much stronger than any MDMA
I have previously experienced. It turns out that 2.0 mg of rilmenidine is a very high dose.
This is much more intense than the 0.2 mg of clonidine. Probably 1.0 mg would be
adequate, and more comparable to a typical dose of MDMA. It also las
ted longer than MDMA.... I took cannabis vapor. Within minutes my heart opened and the rilmenidine
fully blossomed. At this point I could not feel the cannabis at all, although I had taken it
only a few minutes before. I was astonished by the experience.
Not because it worked, I had already seen the clonidine work. I was astonished by the depth of the experience,
and I remained astonished for two weeks. I was ecstatic. Not ecstatic because it worked,
rather the mental state was ecstatic, somewhat un-sober. I recalled Martin Ball calling 5-MeO-DMT
the “crown jewel of the entheogens”. I felt that rilmenidine must also be a
crown jewel. I described the state with superlatives.... Qualitatively, it is very hard to
characterize the rilmenidine state, apart
from the depth of it. At 3:52 hours she asked me
how I feel, and I responded “It is like a peaceful lake, it feels eternal... in a peaceful
sense”. Perhaps most telling, just 25 minutes after taking the cannabis, 3:55 hours after 36 taking the rilmenidine, I
spoke to my wife about what for me were the core issues in our
relationship. These are things that are very hard to discuss because they are painful, and
discussion tends to lead to anger. But we discussed it peacefully. I expressed my sadness
with tears. I believe this capacity for calm contemplation and discussion of painful
personal issues is a core feature of the entactogenic state of MDMA, and here I was
experiencing it with blood pressure medication.... For me it’s really, astonishingly
among the best psychedelic experiences I’ve ever had. Unbelievable.
(Shulgin 2016)
Pharm 2,
p. 26-27