LSD is a classic and it's entirely artificial (and one of the safest substances on earth).
No it's not entirely artificial, it's semi-synthetic because the lysergic acids exist in nature.
LSD is a classic and it's entirely artificial (and one of the safest substances on earth).
What about natural psychedelics like Belladonna, Henbane and Jimson Weed?
What about natural psychedelics like Belladonna, Henbane and Jimson Weed?
The only reason I prefer the classics is they have established safety profiles from long histories of use. Any drug, artificial or not, can be worthwhile if it has an established safety profile. LSD is a classic and it's entirely artificial (and one of the safest substances on earth).
No it's not entirely artificial, it's semi-synthetic because the lysergic acids exist in nature.
No it's not entirely artificial, it's semi-synthetic because the lysergic acids exist in nature.
From my adventures into RC tryptamines which I have mostly enjoyed I have come back to shrooms and DMT. Liberty caps are special, far more so than cubensis.
I took some last year after quite a while and I realised for me there is just an x factor to them the synthetic tryptamines I have had don't have. I think cubensis and 4 aco dmt are fairly close though. Maybe it is the beocystin?
There are some synthetics that don't feel too good had toxic feelings and weird twitches on 5 meo dipt and 4 ho met before which is quite disconcerting.
Couldn't you say all tryptamines are semissynthetic because tryptamine exists in nature; and all phenethylamines are semisynthetic because phenethylamine exists in nature?
I don't think that makes sense - lsd as a molecule isn't found in nature (yet) so has to be synthesised. We don't say 25i is semi-synthetic because it shares parts of its skeleton with mescaline do we? (edit: and what red said )
Well he was modifying lysergic acid which is already found in nature. Can you really call that entirely synthetic?
What does "entirely synthetic" even mean? There's no gradations. Either it's naturally occurring or it isn't.
'Total synthesis is the complete chemical synthesis of an organic molecule from simpler pieces called precursors. It usually refers to a process not involving the aid of biological processes,[1][2][3] which distinguishes it from semisynthesis.'
Drugs derived from natural sources are usually produced by harvesting the natural source or through semisynthetic methods: one example is the semisynthesis of LSD from ergotamine, which is isolated from ergot fungus cultures.