My first reaction to this thread was maybe they're feeling some euphoria from the alcohol, and i was gonna ask if anyone had compared the "vodka" carrier to water in same concentration but then i remembered that the initial FDA filing of Reckitt for Suboxone and Subutex was before they even had any designs for the tablets and all of the initial human studies were done with solutions of alcohol and water. I'll see if i can find the concentration. But you guys are on to something here and reading it made me rummage around and find the 50-odd 8/2 tablets of the rock-hard Amneal generic Suboxone. I've been using tiny amounts for an 18-year-old (4 kg) cat with the pains of aging and who seems to benefit greatly from my home-made water solution sprayed into his mouth with a 29 gauge insulin needle with tip broken off so it sprays a mist and he can easily handle 0.1 ml of the spray without choking or suffocating, but 0.2 ml is quite a lot for him makes him gag. The strength i mix up for use only in my cats as needed for pain or complaining is one-half of the Buprenex strength, where Buprenex ampoules from the vet are 0.3 mg/ml, so i'm giving him 0.015 mg, or 15 mcg. The reason for the half-strength is that it's difficult to measure exactly 0.1 ml and i don't want to give more than he really needs.
Here's how I prepared my last batch, which is a huge amount for one elderly cat. Use a pill cutter to break it into pieces and then dissolve one 8/2 Suboxone in 50 ml of distilled water. 8 mg/50 ml = 0.16 mg/ml. Buprenex is 0.3 mg/ml and it's commonly prescribed by veterinarians who dispense pre-filled 1-ml oral syringes with usually either 0.1 ml or 0.2 ml of Buprenex for house cats with severe pain. So my minimum dose is half of what the vets commonly prescribe but he's getting it sometimes on a daily basis and maybe just for his "comfort" or opiate maintenance as it's now defined in federal law.
Originally I was using an oral syringe to squirt 0.2 ml at a time of the solution but it made him gag. So for a long time it was just 0.1 ml at a time giving him a dose whenever he seemed to needit or i just wanted him to get some sleep and leave me alone. Anyway, spraying just 0.1 ml into his mouth with an insulin needle with needle broken off seems to be the best approach. I hardly ever give him that more than twice a day.
Back to my real interest in this thread. It's been so long since taking them that I might as well give it a try to take the Suboxone for my own opiate maintenance needs after a few years of MMT from a clinic i've written about here very recently, and then a year to taper down to zero on my own, and then a year or two of just kratom, and i've been coming around to the realization that the kratom and the poppy pods are just not enough for me to be a fully functional person, and getting high is the furthest thing from my mind, i just want to have the energy to get up and do thinsg instead of a never-ending fatigue and tiredness that reliably disappears for at least hours when i take one of the precious 60-mg codeine tabs stashed away for emergencies, and this emergency was my needing to know if i'd feel energized by taking a "real" opiate because the kratom doesn't do anything and the poppy pods have other alkaloids in there that cause sedation.
So. I want to get the most out of the 8/2 Amneal hard-as-rock and so that means either or both grinding them into powder in a mortar & pestle and putting the powder under my tongue, or dissolving that powder into an alcohol/water solution. What advice and facts and experience can you people offer me?