Fire&Water
Bluelighter
- Joined
- Jun 8, 2011
- Messages
- 7,665
No, not Boston Red Sox fan terms...
Since Cimetidine is only available via prescription where I live, does Grapefruit juice the same trick in a diminished way?
I'm just curious because this could help me with tapering down my Bupe before switching to Kratom.
Thanks!
I've been on 16mg for over 3 years. Recently, I got myself down to 8mg. I've been straight on that level for about 3 months. Then, I read about cimetidine. Good god! I tried ethanol solutions before this discovery, and it helped a little but mostly with quick absorption. Cimetidine really really really works though. My first day, I used 4mg with tagamet and i felt like i had taken 16mg. I was nodding off every 10 minutes.
My method - I dose 600mg cimeditine an hour before my sub dose. then I follow every 6 hours with 400mg cimetidine. I can do this for about 36 hours before I feel like I can't feel the sub. I also kill about 24oz of WGFJ before and after taking the sub. About an hour after I dose, I really can't stay awake. I'm guessing I'd be fine to drop my dose down given my level of intoxication.
So, for the next three days, I've repeated (4mg/day + cimet). I'm saving so much money. Tomorrow I plan on dropping to 3mg and doing 4 days and trying to drop to 2 and see where I'm at. I want off suboxone, hope this discovery helps me do what I haven't been able to for years now, quit.
One thing this answers maybe - long-term maintenance users of sub CAN get high off of their bupe dose when mixed with Tagamet/cimetidine....really high from my experience.
Im well aware of the potentiation action to certain opioid / benzos you are referring, but if you are nodding on 4mg bupe after taking 16 mg daily for over 3 years, youre a freak of nature...
and less is more, but not that much more !
I think less only "presents itself" as more. What I mean is that if you are on a dose that keeps you above the threshold of opiate agonist effects for yourself - 1 reason I believe its so heavily disputed is personal reactions to this medication vary far more on basis on body chemistry than more conventional opiates/opioid meds, I digress b/c the questions are intriguing on Bupe's ability to mess with you opiate receptor system, so history of Sub use, history of past opiate use, body chemistry, etc. make it a tricky drug to dose properly for anyone, and I am not trying to get into that - then you are steadily going to feel the full agonist effect and it will not dip low enough to cause withdrawal symptoms. On the other hand, if you take small doses, you end up actually noticing the difference from dose to dose. You get the opiate buzz that Subs are capable of giving, then over the next several hours it drops back below the level of it to work as an agonist so you feel kinda crappy, redose and you feel better.
I can't be sure how effective it is, but from what I read it does the same thing.
1 dose of suboxone (no matter what the mgs) should hold you for 24hrs... So I dont know what you're talking about.I took 1mg of suboxone sublingually yesterday at 6pm and its now 10:30am and I am still feeling it strongly, and last night I slept like a baby when usually I suffer from insomnia. Without using cimetidine 2mg of suboxone will barely hold me and keep me well, I certainly would not be feeling it the next day.
You dont need to dose twice a day, you can do it once and be fine. Its totally in your head.Believe it or not, people have different physiology and metabolize drugs at different rates. I dose my Sub 2x/day. Less than that and I get very uncomfortable. I only take a total of 4mg now, but I dropped from 8mg and you are not going to tell me I didn't experience withdrawal.
People are different. I suggest not generalizing so much.
And by the way, anyone taking over 4mg a day has no clue what they're doing. Its pointless taking these high doses I'm hearing... Like 16-24??? WTF
You dont need to dose twice a day, you can do it once and be fine. Its totally in your head.