Should be fine.
At any rate it should remain active, doubt the naloxone would decompose. Typically I do not let my endeavours in opioid/opiate chemistry (of the phenanthrene, morphinan family, such as morphine derivatives, codeine/dihydrocodeine chemistry, or anything else in the family run over 50'C, I try to keep it to less actually, if I can. but that is being extremely conservative, because very precious and sometimes both extremely difficult to come by, available only in limited quantities, usually far from cheap and in many cases requiring extraction and purification prior to being used, several, or indeed all of the above. I do not believe it necessary for the vast majority of compounds. Its usually not the reactions, but stripping solvents. Depends on the reaction, the solvent and the opioid, but things have been run at 70-80'C before (morphine to alpha-chloromorphide, the distillation off of the solvents afterwards did not harm the batch of alpha-chloromorphide. It was still as active when done in a higher boiling solvent, removed post-rxn without resorting to vacuum As when using acetone or ether. Albeit active in a fucking weird ass kind of way, but that is the character of alpha-chloromorphide, not anything to do with how cold or hot the reaction ran at.
And H may be smoked, as long as its mixed with caffeine. So I doubt a hot day is going to destroy it Although one caveat is that the alpha-chloromorphide, dibenzoylmorphine, heroin and prope were in crystalline form, aside from when dissolved in solvent. They have survived evaporation of the solvent down to dryness, albeit carefully, but using heat, I think ambient temperature would have to be very, very hot for quite a long time before destroying the drug.
