Would taking a stimulant like say an amphetamine or cocaine cause a seizure in someone taking antiseizure medications regularly, but not taking the antiseizure medications for the purpose of preventing seizures (offlabel).
Examples: Topamax (for headaches) +methamphetamine or pregabalin ( for anxiolytic purposes) + cocaine.
Would the above by increasing glutamate rapidly override the anti-seizure effects and in fact precipitate a seizure by causing a huge increase in activity in different areas of the brain formerly dormant?
Examples: Topamax (for headaches) +methamphetamine or pregabalin ( for anxiolytic purposes) + cocaine.
Would the above by increasing glutamate rapidly override the anti-seizure effects and in fact precipitate a seizure by causing a huge increase in activity in different areas of the brain formerly dormant?