Stimulants Stimulants (Cocaine, Meth, Adderall etc)

[armyranger516]

Hello everyone, I am writing a couple essays and articles for my class assignment and I cannot find any information on tolerance one can have? Like if one individual has built up tolerance or become used to a drug for example we will go with Methamphetamine and then switched to another stimulant like Cocaine or Adderall or any other stimulant for example will the individual develope more euphoria or have a stronger effect for the individual because it's a new drug? Will it effect them differently or anything? I appreciate any info or places to find such info. Also could one show a good information place for stimulants in general? Thanks a bunch all!!

 

[tweakerguy]

Are you talking about cross tolerance? Yes its a real phenomenon.
It's most likely a [X] receptor issue. Two very different drugs from a synthesis perspective, targeting the same area of our brain more or less. I had a psychiatrist refuse an adderall scrip after learning of my recent (at the time) discovery of meth.

Best case scenario, it would've been a waste of time trying to treat ADHD with another stim at that point.
From a liability perspective, he was obviously covering his ass. Don't mix these drugs.

 

[Jabberwocky]

One thing worth noting about stimulants, euphoria and tolerance is that there are two kinds of tolerance. One is your permanent baseline ability to feel euphoria. When you first begin on stimulants this is non-existent and you will frequently feel euphoria. The other is what you could call your sessional tolerance which builds up over the course of a binge until further additions of more stims has no noticeable effect. If you take a break - maybe from a day to several weeks depending on multiple factors - your sessional tolerance will reset and the stims will get you high again and you’ll be good to party. Sleep is the number one thing for this kind of tolerance to reset. However, with each use your baseline tolerance creeps up reducing your ability to feel euphoria and no amount of time will reset it (maybe a few years if you are really lucky). It’s because stim use has long-lasting to permanent structural effects on the brain and the way you dopamine, serotonin and norepinephrine systems function.

Increased tolerance also seems to allow for stimulants to have paradoxical effects for some people, where they feel tired from increased doses after a certain point.

This can be explained in a far more complex way with reference to various different neurotransmitters and receptors but you get the gist.

 

[armyranger516]

Are you talking about cross tolerance? Yes its a real thing and stimulants are particularly easy to fall into between each other.
A psychiatrist straight up told me that once when i asked about getting on one.

Yes that's what I'm talking about, thank you!! Thanks guys I appreciate it very much!!

 

[tweakerguy]

Yes that's what I'm talking about, thank you!! Thanks guys I appreciate it very much!!

God dammit lol you quoted me while i was editing my reply
Ah well.

 

[Jabberwocky]

I had a psychiatrist refuse an adderall scrip after learning of my recent (at the time) discovery of meth.

He sounds a bit outdated. My psychiatrist took my meth habit as a symptom of ADHD and thought Rx stimulants were both logical and necessary. Only after passing a drug test proving I was a month (I think) off meth first though to comply with government reglulations.

 

[tweakerguy]

He sounds a bit outdated. My psychiatrist took my meth habit as a symptom of ADHD and thought Rx stimulants were both logical and necessary. Only after passing a drug test proving I was a month (I think) off meth first though to comply with government reglulations.

This was probably 2001. But either way he was a little old school if memory serves.
My guess is he assumed if i'd already been "experimenting", it was only a matter of time before i'd use it again.
He was right.

 

[wudbutcher]

He sounds a bit outdated. My psychiatrist took my meth habit as a symptom of ADHD and thought Rx stimulants were both logical and necessary. Only after passing a drug test proving I was a month (I think) off meth first though to comply with government reglulations.

Did ADHD meds help you? I've thought for decades now that prescribed stims would have been just the thing for my psyche. Alas, hit the dark side very early, yet maintained for 30 yrs quite well. Interested to know how it worked for you after meth habit.

 

[Jabberwocky]

Did ADHD meds help you? I've thought for decades now that prescribed stims would have been just the thing for my psyche. Alas, hit the dark side very early, yet maintained for 30 yrs quite well. Interested to know how it worked for you after meth habit.

Rx adhd stims (dexedrine) absolutely changed my life. I took only the prescribed dose for near 5 years and became very focussed and productive in all aspects of my life. I went back to college and did a Masters and started working for voluntary organisations in the community, met a nice woman and was with her happily for 4 years.

My moods settled down and my personality became very chill and I felt fairly together and happy first time in my life. One interesting side effect was I started to really dislike alcohol and stopped drinking altogether.

I was also taking a low-dose antipsychotic to control my bipolar mania and it was only because I stooped taking that and went manic that the whole thing came off the rails and I hit the meth again after 5 years.

 

[tweakerguy]

Doesn't meth use exacerbate
the mania? Is your bipolar medication just incompatible with stimulants?

*oops* missed where u said antipsychotic.

 

[wudbutcher]

Doesn't meth use exacerbate
the mania? Is your bipolar medication just incompatible with stimulants?

*oops* missed where u said antipsychotic.

I took Lexapro 10 mg daily for 17 years all the while dabbling in stims. Met a nympho supermodel pornstar, with issues like myself oh, and went off the rails for a year-and-a-half. Daily use. Still maintained the business side and the bedroom side oh my God, but things ended in disaster. Trying to rebuild as we speak drug free

 

[wudbutcher]

Also I neglected to mention, and in hindsight was probably a big contributing factor. My doc switched me from Lexapro to Wellbutrin at the beginning of that last year. Thought that Lexapro has stopped working. Wish I had just doubled up on my dose, has 20 mg daily is not unheard of. So said that I was a different person. I've always battled depression, cuz we're the greatest thing in the world or so I thought at 13. Kept the lid closed on the Jack in the Box it seems I was born sitting on LOL. Very grateful for the insight I stumble upon here on BL

 

[Jabberwocky]

Doesn't meth use exacerbate
the mania? Is your bipolar medication just incompatible with stimulants?

*oops* missed where u said antipsychotic.

Yes. That’s right. I was drug free, stopped the BP medication, went manic, took meth because I was manic, and then the while thing became a giant snowball with mania demanding meth and meth fuelling mania. Strangely, my BP meds function fine with Rx doses of dexamphetamine and I get the therapeutic benefits no problem but the meds block out a lot of the euphoric high from meth.

 

[2spun4one]

I was a multiple times per week cocaine user for over 15 years, when I started using meth, I lost all desire for cocaine, basically never thought about it again.... I've been an extremely heavy meth user now for over 3 years, 2-3 grams daily, every single day. If I was to stop using meth, for whatever reason, cocaine would do little for me.

 

[WellTram]

Try modafinil.

 

[SoonAJunkie]

Meth will work but don't expect to not have any issues of whatever kind at all,addictin/binge-wise.

 

[exxsinn]

I was and am a heavy user of stimulants. I have used amphetamines daily for 4 years, about 600/800mg per day. I have used meth literally once as an experiment but I don't believe you'll live long doing that regularly so I left it.

I will answer any questions to your thesis but I'm not gonna type. Hit me up in a PM to get some details for a phone interview.

I'm 35

 

[jjeez]

I was a multiple times per week cocaine user for over 15 years, when I started using meth, I lost all desire for cocaine, basically never thought about it again.... I've been an extremely heavy meth user now for over 3 years, 2-3 grams daily, every single day. If I was to stop using meth, for whatever reason, cocaine would do little for me.

Does this have to do with the over all strength of meth over coke or completely different because of the way the drug interacts with your brain?

 

[jjeez]

I was and am a heavy user of stimulants. I have used amphetamines daily for 4 years, about 600/800mg per day. I have used meth literally once as an experiment but I don't believe you'll live long doing that regularly so I left it.

I will answer any questions to your thesis but I'm not gonna type. Hit me up in a PM to get some details for a phone interview.

I'm 35

600-800 mg of amphetamines? Like adderall? I thought the top dosages were around 60-80mg? Or am I not remembering correctly? Or is this a different type of amphetamine?

 

[2spun4one]

Does this have to do with the over all strength of meth over coke or completely different because of the way the drug interacts with your brain?

Yes, it has a lot to do with that. Basically the high from meth is not as intense or as immediate as cocaine, lasts a lot longer, and does not have you craving more as quickly as cocaine does. With cocaine, the urge to do more is almost constant. And meth gives you feelings of confidence and energy levels that cocaine does not...