I tried this a few times, so this is only what happened to me and may not to others.
I took st johns wart before I went out, and it did limit the effects of my pill. Kinda like when you drop for the second night in a row. The second is not as intense and doesnt last as long.
I took St johns wart afetr a big night and the following weeks and it helpd my brain recover A LOT.
I know that might not help anyone....just what happened to me.
**I had a broken watch once, It was right, twice a day**