I find it very hard not to lose weight on Dexedrine, especially at the beginning. If I just eat whenever I feel like it, I will drop 15 pounds in the first 2 months, which usually leaves me underweight. I am currently on a stable dose of Dexedrine and at a healthy, stable weight. I take my Dexedrine as prescribed for ADHD, I do not advocate using prescription stimulants without a prescription.
I am mildly amazed and distrustful when I see doctors claim that amphetamines aren't effective for weight loss. It is probably a disingenuous message - the true message is that amphetamines are not safe for weight loss. They will probably be effective, if you give a large enough dose. The studies that showed no benefit gave very low doses, especially considering how fat the patients were. Big fat patients do need a larger dose of amphetamine to get the same effects, although the dose is probably not exactly proportional to body weight. If you have a big body, the drug will spread out and get diluted in all your fat.
I am mildly amazed and distrustful when I see doctors claim that amphetamines aren't effective for weight loss. It is probably a disingenuous message - the true message is that amphetamines are not safe for weight loss. They will probably be effective, if you give a large enough dose. The studies that showed no benefit gave very low doses, especially considering how fat the patients were. Big fat patients do need a larger dose of amphetamine to get the same effects, although the dose is probably not exactly proportional to body weight. If you have a big body, the drug will spread out and get diluted in all your fat.