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So... Ibuprofen kills a cannabis high while retaining medicinal benefits

《Plasticity》

《Plasticity》

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I was watching an episode of the Joe Rogan Experience a while back and he had this very chill neuroscientist/addiction specialist on. He's not your typical know it all douchey "Dr. Drew-esque" addiction specialist though, he focuses on keeping your drug intake to a minimum and developing skills to use in moderation, rather than forcing anyone to stop. Irrelevant to my question but I just found his overall approach to addiction treatment a nice change. I reccommend watching the podcast even if you're not fond of Mr. Rogan.

Anyways, he claimed that Ibuprofen effectively decreases one's cannabis high and has recommended it to all his patients having uncomfortably intense highs, whom all drew the same conclusions. After a google search It appears that this has been backed up by a semi-recent study done on mice . Has anyone tried this with similar results? If not then I think this would make for an interesting experiment. At the least it's a valuable piece of information to know. I'm on a break right now and don't even have ibuprofen so no experiment for me, at least for now.

Depending on how effective it is at killing your high this could be a godsend for med patients who want the full spectrum benefits of cannabis. Not only is there additional pain relief from the ibuprofen, but also decreased inebriation and without memory issues associated with heavy toking. It seems like something that should be common knowledge, so if it is forgive me but I couldn't find a thread on bluelight so here it is.

Links and such...
NSFW:
Ibuprofen Can Kill Pot Buzz, Research Reveals
http://www.alternet.org/drugs/ibuprofen-can-kill-pot-buzz-research-reveals
researchers at the Louisiana State University Health Sciences Center and publishedin the Cell journal, chemicals in the over-the-counter painkiller allow the plant's therapeutic benefits to kick in with no buzz, no memory loss and no loss of motivation. The findings could help provide a way for patients who use marijuana to combat pain but who don't like to get stoned, find relief. And they could expand other legal treatment options for people suffering from chronic disease
Click to expand...

Ibuprofen Kills THC Buzz – Suppressing Marijuana Memory Loss
http://m.marijuana.com/news/2013/11/ibuprofen-kills-thc-buzz-suppressing-marijuana-memory-loss/

Pot + Ibuprofen = Medicinal Bliss
http://www.hightimes.com/read/pot-ibuprofen-medicinal-bliss

The podcast: JRE 629, Andrew Hill PhD
[video]https://youtu.be/06olLYiMvM4[/video]
 
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What is it about the Ibuprofen that kills the buzz? I'll never chance taking advil cuz my mom is allergic and I don't wanna risk.

Sounds interesting if it works tho.
 
Interesting :\ I'll try it out coming weekend, will report back

*edit* I'm not sick though, so won't be able to comment on the medicinal properties, but I wonder if it could really kill a high
 
I've used a lot of Ibuprofen in various forms (Advil liquid caps / Advil / Nurofen(+) / various generic brands) because of various muscular and skeletal disorders while being high on various strains of Cannabis (you know, more stoning types / high ones / strengths etc.) and never noticed anything that would indicate such a remedy if I would call it that, since you have to understand that your Cannabis high will be smoothened out in the case Ibuprofen will begin to be absorbed by your body and begins to work so it is IMHO a not false claim, but rather a soothing mental effect on the Cannabis high when it is taken immediatly after felling too stoned / high. just my €0.02 :)

-- Peace o/
 
Strange because I have been on Advil while on weed and I never found any decrease in my high.

I'm not saying it's not medically true, but I didn't find it to be the case so I'm not sure why.

Maybe it depends somewhat on the individual.
 
I cannot remember any occasion on which ibuprofen lessened my high...
 
The only problem I have with this is that everything I use Ibuprofen for (inflammation, joint pain, etc), marijuana does a better job of medically treating on it's own.

Now I know Ibuprofen is over the counter, but that doesn't make it any safer than pot. Many researchers suggest that Ibuprofen increases the risk of heart attacks, something that marijuana does not do.
 
I use ibuprofen a few times a month (for headaches, inflammation, pms, hangovers etc) and have never noticed any decrease in the weed high. Interesting links btw.
 
Thanks for post.

Does this have to do with cox II inhibition?

Good stuff
 
Tried this twice past weekend, no noticeable change in the high for me...
 
I watched that episode too and it was pretty interesting but haven't really felt a decreased psychoactive effect .

I've read that ibuprofen helps with the short term memory loss from cannabis but i don't think it has the ability to stop the cannabis high, i believe it just gets rid of the negatives like the memory problem. But again i don't really have a lot of experience with that, would be interesting to try it.

Ibuprofen acts in the cannabinoid system IIRC so it could very well have some interactions with cannabis.
 
Mycophile said:
Strange because I have been on Advil while on weed and I never found any decrease in my high.

I'm not saying it's not medically true, but I didn't find it to be the case so I'm not sure why.

Maybe it depends somewhat on the individual.
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advil is ibprofin. There was a study done one acetaminophen I read recently showing it blunted emotions. Acetaminophen is not an nsaid even though it has anti inflammatory effect. It's quite an interesting find in my opinion.

Edit : Myc is right I mixed advil and aleve. My bad
 
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How about Bextra and Vioxx, Celebrex etc? Maybe those are stronger as they are Cox II inhibitors. They don't work the same as basic IBP's that are sold over the counter.

Also, THCa is available in non psychoactive tinctures for inflammation which also works in inhibiting Cox II in some way and releasing Cox I which have to do with inflammation as well.
 
tacodude said:
advil is naproxen not ibprofin. There was a study done one acetaminophen I read recently showing it blunted emotions. Acetaminophen is not an nsaid even though it has anti inflammatory effect. It's quite an interesting find in my opinion.
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I am almost sure that's not right.

ALEVE is Sodium Naproxen while Advil is Ibuprofen.

I am almost certain of it.

Anyways, this might be an interesting idea but I just personally don't feel it has that effect on me so I am a bit skeptical.
 
tacodude said:
advil is naproxen not ibprofin. There was a study done one acetaminophen I read recently showing it blunted emotions. Acetaminophen is not an nsaid even though it has anti inflammatory effect. It's quite an interesting find in my opinion.
Click to expand...


You are incorrect Sir:


Wikipedia:

Advil is a brand of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID). Advil is manufactured by Pfizerand has been on the market since 1984.


The active ingredient in Aleve is the non-steroidal, anti-inflammatory drug (NSAID) naproxen sodium; each dose contains 220 milligrams of the drug.
 
w01fg4ng said:
The only problem I have with this is that everything I use Ibuprofen for (inflammation, joint pain, etc), marijuana does a better job of medically treating on it's own.

Now I know Ibuprofen is over the counter, but that doesn't make it any safer than pot. Many researchers suggest that Ibuprofen increases the risk of heart attacks, something that marijuana does not do.
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Sorry but that's bullshit, marijuana increases your heart rate and can induce permanent tachycardia increasing your chances of heart conditions drastically. I like to blaze as much as the next guy but let's all stop pretending weed is completely harmless.
 
swimmingencouraged said:
Sorry but that's bullshit, marijuana increases your heart rate and can induce permanent tachycardia increasing your chances of heart conditions drastically. I like to blaze as much as the next guy but let's all stop pretending weed is completely harmless.
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It's actually probably NOT bullshit.

It's true that weed isn't harmless but I have never heard of a case of PERMANENT tachycardia (not saying it can't happen).

I bet you that if you take a perfectly healthy person and have them smoke weed everyday of their life or take high doses of Advil every day of their life they will end up with more problems from taking that much Advil.

Really high doses of NSAIDs are not supposed to be good for you on multiple levels.

I got gastritis that lasted for 9 months from taking Aleve everyday for 3 months after a knee surgery and have been on Prilosec ever since which isn't all that great to be on for years unless you have to.

Weed has never led to me needing to take a medication for a health condition, except some asthma but I've always had asthma and it went away when I stopped.
 
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Yeah I would like a source on that "permanent tachycardia" claim too.

swimmingencouraged said:
I like to blaze as much as the next guy but let's all stop pretending weed is completely harmless.
Click to expand...
Noone here claimed weed is harmless. All I claimed is that there is no proof that marijuana has a direct link with heart attacks. We simply don't have enough study to make that kind of assumption.

What we do have enough study on is Ibuprofen. Not only can it cause heart attacks, but it can give you ulcers and kidney damage.

Ibuprofen HAS been proven to "cause damage to the kidneys (nephrotoxicity), worsening of heart failure, and even heart attack or stroke. Outside of the cardiovascular system, its major risk is to the stomach, where it can cause ulceration and gastrointestinal bleeding."
http://www.ucsfhealth.org/education/heart_disease/

The point of my post is to show you that Ibuprofen could potentially be worse for you than pot.

If I truly thought pot was harmless, I would not be on this forum.
 
"Ever since describing a non Q wave acute myocardial infarction in 1979 after cannabis consumption, atrial fibrillation episodes, ventricular tachycardia (VT), ventricular fibrillation, angina pectoris, and acute myocardial infarction have been reported and are directly related to consumption of this substance."

I'm not trying to say ibuprofen is better than weed or is not harmful. I'm well aware of the risks involved with most NSAID medications. And I'm certainly not advocating them so I'm not sure what justified these responses including studies on it? Like shit I like weed too cool them jets. I'm just saying chronic marijuana use is also harmful and although there are no studies on its direct link to heart conditions the information is available to make an educated assumption to that effect. Look at any other drug that increases ones heart rate significantly and tell me it's not hard on your cardio vascular system. Marijuana is no different in this regard.
 
^ That's an interesting study, however done on a heart transplant patient with previous heart conditions.

swimmingencouraged said:
I'm not sure what justified these responses including studies on it?
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It has little to do with you, and more to do with the thread. The way I look at it, more people see Ibuprofen as "harmless", especially when it's compared to a controversial drug such as marijuana. This can be a very bad mistake.

Getting back on topic:
The notion to take more drugs to treat side effects from another drug is generally a slippery slope. Too many doctors I see prescribing more drugs because of side effects from another. It's truly a never-ending process that leaves the patient in misery and a mouth full of pills.

Pick ONE drug that works the best for you. Fuck everything else.
 
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