LOL, I just found this interesting little read:
http://www.maps.org/research-archive/w3pb/2008/2008_Passie_23067_1.pdf
There are a few studies out there that show mescaline increases both serum growth hormone (good) AND prolactin (bad).
THIS study found psilocybin had "no significant effect" on either hormone and suggested that DMT increases prolactin and cortisol levels (bad).
My understanding of biochemistry is quite rudimentary and I'm tripping on 2C-E as I type this. Which brings me to my next point... I wonder what the story is with the 2C-x series?
My theory is that phenethylamines (but probably not tryptamines) have an inherent hGH-releasing quality to them. Unfortunately it seems they stimulate prolactin release as well.
LSD is a phen but it's also an ergoloid and these tend to be powerful prolactin inhibitors (if you read the MAPS study it seems LSD itself is a powerful prolactin inhibitor in male rats). Seems to me that its nature as an ergoloid counters the (likely) prolactin-elevating properties of its structure as a phenethylamine.
Can anybody explain any of this to me? Can B6 be used to take care of increased prolactin from phenethylamine psychedelics?
http://www.maps.org/research-archive/w3pb/2008/2008_Passie_23067_1.pdf
Great. Like I needed another excuse to trip! 8)In humans, LSD increases serum growth hormone with a peak at 120 min. but does not alter serum prolactin levels
There are a few studies out there that show mescaline increases both serum growth hormone (good) AND prolactin (bad).
THIS study found psilocybin had "no significant effect" on either hormone and suggested that DMT increases prolactin and cortisol levels (bad).
My understanding of biochemistry is quite rudimentary and I'm tripping on 2C-E as I type this. Which brings me to my next point... I wonder what the story is with the 2C-x series?
My theory is that phenethylamines (but probably not tryptamines) have an inherent hGH-releasing quality to them. Unfortunately it seems they stimulate prolactin release as well.
LSD is a phen but it's also an ergoloid and these tend to be powerful prolactin inhibitors (if you read the MAPS study it seems LSD itself is a powerful prolactin inhibitor in male rats). Seems to me that its nature as an ergoloid counters the (likely) prolactin-elevating properties of its structure as a phenethylamine.
Can anybody explain any of this to me? Can B6 be used to take care of increased prolactin from phenethylamine psychedelics?
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