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  • BDD Moderators: Keif’ Richards | negrogesic

Simulants - Cant get high after smoking meth for 2 days straight?

C

ComfortablyScum94

Greenlighter
Joined
Jun 12, 2021
Messages
8
Hello everybody. I can't find anything on this topic on the internet so i figured i'd come here and post myself. So basically, i use to be able to smoke for 3 or 4 days straight and still feel it a little bit toward the end there. I've been clean for almost a year and i decided to pick up again, i smoked for 2 days and tonight is night 3. But even last night, i couldnt get high! Its the weirdest thing. People go on 10 day binders and still get high, but i cant after just two days? What gives! I puff big cloud after big cloud and absolutely nothing. It may be worth mentioning that i am currently taking Seroquel and Antabuse so i dont know if they would interfere in any way? I know when i was taking Neltrexone i couldnt get high at all. I still get a racing heart rate, elevated skin temperature and dry mouth but these effects only last about 15-20 minutes. And the shit was getting me high when i first started smoking it but not nearly as high as i use to get. I haven't felt that "oh fuuuuuuuck" rush of meth in a while. Maybe its the stuff on the street these days? anyways, im hoping its just because i depleted all my dopamine and serotonin. thanks
 
ComfortablyScum94 said:
I feel that, lol. I probably should stop. but will i? LOL. i still have a little left. i use to get high after 2 nights though, all the time. Just not right now.
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also, i acually did sleep last night for like 7 hours and i ate a meal. and the night before i got 4 hours. still nothing
 
The full meth experience is complicated and depends on at least three neurotransmitter systems: dopamine, norepinephrine, and serotonin. Seroquel is an antogonist of all 3 receptor types and interacts in a complicated way with meth. At 50 mg it is theoretically primarily a histamine antagonist but there is a lot of anecdotal evidence that even at that level it prevents some parts of a meth high.

In many people, they will experience wakefulness for up to 48 hours and pro-sexual effects but no euphoria if they have not used for a while but take seroquel. After 48 hours they can barely get anything out of meth.

Chronic abuse of meth over time can also permanently reduce the sensitivity of these 3 systems. Acute abuse of meth can temporarily reduce their sensitivity. People with a history of chronic abuse tend to get shorter available periods of acute abuse before they become desensitised/tolerant.
 
I did a 150mg line earlier as a one off to prevent me from taking MDMA today and I'm high!! I was on abilify the last time i did meth and MAN!! Huge difference!! I did a lot less too! I probably didn't even get this high from half a gram with the abilify. I keep reading about rc's bc I've been off the market for a few years. Looks like some promising new shit! Lately I'm off all meds and having excellent results with meth and MDMA. I'm thinking about trying some a-phip. I haven't let myself get like that since a-php first was around for me in like 2013 or 14.
 
ComfortablyScum94 said:
50 mg. i figured that was what it might be. i haven't taken it the last few nights though
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Drugs like Seroquel have an action in the body which is sort of exponential. You take 50mg per day but wind up with say like 5000mg in your bloodstream after a couple weeks. Thus why most antidepressants and and antipsychotics and the like take a couple weeks to truly take effect. It's a buildup through your bodies biochemical reactions to these types of drugs. Only a few days off isn't gonna reduce the blood serum level enough to get high again, yet.

I suggest you stick to your Seroquel and not the meth. Psychosis is not fun. It's absolutely insane actually.
 
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