Benzos Question about diclazepam freebase ...

[waffle-head]

Hi

I purchase diclazepam 'freebase'. It's described as freebase in the description. A very reputable vendor.
What does this mean?
I mean, I can still ingest it orally in a gel cap can't I?

Thanks.

 

[speedballs_over]

It means your supplier is an idiot. I wouldn't buy from them. They're is no freebase for most benzos, they aren't polar molecules, can't be formed as salts or freebases. No HCl / sulfate / citrate / tartrates / etc..., i.e. no salts, no associated freebase.

A few exceptions exist, the most well known being chlordiazepoxide HCl, and a few others. The vast majority of benzos aren't "able" to form salts.

 

[white55]

Not 100 percent true, nifoxipam is also sold as a hcl salt.

 

[kleinerkiffer]

We had a thread about it a few month ago

Most drugs generally are salts such as HCl yes, but benzos are notoriously hard to make into salt and a lot even unrealistic though there are some exceptions - most are freebase instead. I don't believe diclazepam is an exception, so it would be a freebase just like I knew most benzo's I have had to be like alprazolam or diazepam powder.
They dissolve well in pure alcohol, though varyingly diluted alcohol solutions can be used. For example I could easily dilute my etizolam from 100% ethanol to 50% without any crashing back out again (I started at a concentration above 1 mg/ml so that diluting would end up at 1 mg/ml) and I believe 40% vodka also worked. However alcohol is volatile and water is too, kinda. I think PG is much less volatile and generally the resort of people wanting to dissolve the average fb benzo, though sometimes injecting is involved which makes it a different story altogether.

Read up a bit, apparently it can take a very long time for diclazepam to dissolve in PG even multiple days. I don't know if warming the solution helps (well I sort of do - it pretty much always does as a general rule of thumb of chemistry), if you do try don't go as far as boiling it.

I do not know the saturation point, choosing say 5 mg/ml may not be quite as hard as 1 mg/ml.

 

[white55]

+1 one on diclazepam being problematic to dissolve in PG. It not so much that it takes days if you use aa warm water bath and some string but it will crash out once the solution cools. I'd stick to 1 mg/ml which should stay in solution at room temp (and take a good look at it before trying to measure one dose just in case). While 5 mg/ml might well not.


As for nifoxipam being sold both as a salt and as a free base is something I can't prove without breaking the no sourcing rule so you can either believe me or not.