dopamimetic
Bluelighter
- Joined
- Mar 21, 2013
- Messages
- 2,070
We have that exotic disorder called 'Pseudobulbar Affect' (PBA) - emotional lability, labile affect (and now it becomes confusing) - emotional incontinence, a condition that seems to mainly occur secondarily to brain injury or a destructive neurologic disease like ALS, MS, Huntington's, etc.
So they are beating around the bush somewhat, as it is not that uncommon when it comes to mental / mood disorders - to differentiate things that can be different but also the same, or the other way round (if you don't understand what I'm trying to say, don't worry, that's intended ).
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I feel there is a major problem in our society that we think of illnesses as isolated cases. Person A is depressed. B has OCD. D has ADHD. E has physical pain. F has Parkinson's. Dependent on what the first diagnosis was, one will get on the one or other route of treatment - 'mentally ill' or 'neurologically / physically ill'. This is hyper-abstracted, but it's a hard reality that influences and sometimes destroys numerous lives.
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Theory: Genetic predispositions cause some people to become more 'sensible' than others. Depending on the environment, childhood, family, peers etc. one may grow up in peace, or somewhen emotions become overwhelming, initiating a one-way road of latent chronic stress, mental as well as physical (inflammation, oxidative stress, etc) --> leading to a fragile personality.
Why do we treat the ones as healthy individuals who just have a coincidence of some weird genetics & need help, while others are 'mentally ill' and deserve their living hell ... !?
(A bit exacerbated, I know. )
PBA may often be misdiagnosed as clinical depression; however, many clear distinctions exist.
In some cases, depressed mood and PBA may co-exist. In fact, depression is one of the most common emotional changes in patients with neurodegenerative disease or post-stroke sequelae. As a result, it is often comorbid with PBA. Comorbidity implies that depression is distinct from PBA and is not necessary for, nor does it exclude, a diagnosis of PBA.
So they are beating around the bush somewhat, as it is not that uncommon when it comes to mental / mood disorders - to differentiate things that can be different but also the same, or the other way round (if you don't understand what I'm trying to say, don't worry, that's intended ).
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Mechanistically, PBA is a disinhibition syndrome in which pathways involving serotonin and glutamate are disrupted. (source)
I feel there is a major problem in our society that we think of illnesses as isolated cases. Person A is depressed. B has OCD. D has ADHD. E has physical pain. F has Parkinson's. Dependent on what the first diagnosis was, one will get on the one or other route of treatment - 'mentally ill' or 'neurologically / physically ill'. This is hyper-abstracted, but it's a hard reality that influences and sometimes destroys numerous lives.
--
Theory: Genetic predispositions cause some people to become more 'sensible' than others. Depending on the environment, childhood, family, peers etc. one may grow up in peace, or somewhen emotions become overwhelming, initiating a one-way road of latent chronic stress, mental as well as physical (inflammation, oxidative stress, etc) --> leading to a fragile personality.
Why do we treat the ones as healthy individuals who just have a coincidence of some weird genetics & need help, while others are 'mentally ill' and deserve their living hell ... !?
(A bit exacerbated, I know. )
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