it does add to opiates, it's hit or miss for alot of people (as in they'll find the gabaergic lends to more of a non synergistic effect, but more so than not, people find they synergize well, i've often said pregabalin shouldn't be underestimated, it's in the same drug catagory as xanax and clonazepam and as of recently, has been placed in the same schedule as those benzos aswell)