Tchort
Bluelight Crew
- Joined
- Mar 25, 2008
- Messages
- 2,392
Question concerning drug interactions in the midst of precipitated withdrawal:
Is Clonidine advisable during the period of ongoing precipitated withdrawal? Leaning towards 'yes', barring the following complications:
1) No other opioid involved aside from differing doses of Buprenorphine; 'Buprenorphine overdose' symptoms (cold skin, sweating, dry mouth, irritability/inability to concentrate, RLS) match closely to 'Buprenorphine withdrawal' symptoms- cold skin, mild fever, RLS, goosebumps, profuse sweating, yawning, nausea/no appetite, etc. All of the above present, matching both lists of 'overdose' and 'withdrawal', leading to the conclusion of precipitated withdrawal through too much Suboxone-- all of which is what eventually led to the extremely ill advised, panic-induced dose adjustments of taking more in the midst of OD/precip. withdrawals over the last 7-10 days. Less concerned with this bit of information since its been 30+ hours since last bupe dose and have no intention of taking anymore until more severe withdrawal symptoms begin (pupil dilation, etc.) and histamine-responses have subsided meaning the excess Buprenorphine has come and gone.
2) Ingestion of caffeine, particularly via chocolate, appears to help the gooseflesh, cold skin and cold sweats for a time. Have ingested regular daily amount of coffee and a bit more chocolate than normal the last couple days. Wondering if there is some kind of anti-histamine type action there. However, caffiene + withdrawal symptoms eventually leads to what you'd expect (been several hours since the last cup of coffee).
3) Also prescribed Mirtazepine/Remeron, which has conflicting reports on concurrent use with Clonidine. Prescribing doctor of all 3 is less than reliable on medical knowledge; I have prior experience with Clonidine before getting on Remeron, thinking about breaking a 0.1 Clonidine into quarters and trying a quarter at a time on this first full day without Buprenorphine.
Anyway, two questions:
-Is Clonidine advisable in precipitated withdrawal in general?
-Is Clonidine at any dosage advisable in the ridiculous scenario outlined above? Figured it might be a good idea due to the various benefits, from reducing RLS, sweating, etc.
Is Clonidine advisable during the period of ongoing precipitated withdrawal? Leaning towards 'yes', barring the following complications:
1) No other opioid involved aside from differing doses of Buprenorphine; 'Buprenorphine overdose' symptoms (cold skin, sweating, dry mouth, irritability/inability to concentrate, RLS) match closely to 'Buprenorphine withdrawal' symptoms- cold skin, mild fever, RLS, goosebumps, profuse sweating, yawning, nausea/no appetite, etc. All of the above present, matching both lists of 'overdose' and 'withdrawal', leading to the conclusion of precipitated withdrawal through too much Suboxone-- all of which is what eventually led to the extremely ill advised, panic-induced dose adjustments of taking more in the midst of OD/precip. withdrawals over the last 7-10 days. Less concerned with this bit of information since its been 30+ hours since last bupe dose and have no intention of taking anymore until more severe withdrawal symptoms begin (pupil dilation, etc.) and histamine-responses have subsided meaning the excess Buprenorphine has come and gone.
2) Ingestion of caffeine, particularly via chocolate, appears to help the gooseflesh, cold skin and cold sweats for a time. Have ingested regular daily amount of coffee and a bit more chocolate than normal the last couple days. Wondering if there is some kind of anti-histamine type action there. However, caffiene + withdrawal symptoms eventually leads to what you'd expect (been several hours since the last cup of coffee).
3) Also prescribed Mirtazepine/Remeron, which has conflicting reports on concurrent use with Clonidine. Prescribing doctor of all 3 is less than reliable on medical knowledge; I have prior experience with Clonidine before getting on Remeron, thinking about breaking a 0.1 Clonidine into quarters and trying a quarter at a time on this first full day without Buprenorphine.
Anyway, two questions:
-Is Clonidine advisable in precipitated withdrawal in general?
-Is Clonidine at any dosage advisable in the ridiculous scenario outlined above? Figured it might be a good idea due to the various benefits, from reducing RLS, sweating, etc.
